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Acesistem (Amiloride)
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Acesistem

Acesistem is a new, orally administered, potassium-sparing diuretic with mild natriuretic and diuretic properties. Its primary site of action is the distal tubule of the nephron where it selectively blocks sodium transport, thereby inhibiting sodium-potassium exchange.

Other names for this medication:
Acuren, Adelphan, Amiloretic, Amiloride, Aquazide, Benazeplus, Bpzide, Cilazil, Coteveten, Crinoretic, Dithiazide, Diuretidin, Dociteren, Drenol, Duopril, Duradiuret, Esidrex, Fosicomp, Gentipress, Hidroronol, Hidrotiadol, Hydrene, Hydrex, Hydrozide, Iperton, Lisiplus, Lorzaar, Monoplus, Pantemon, Propra, Quinaplus, Rethizid, Ridaq, Rofucal, Selokomb, Tiaren, Tiazid, Timolide, Triampur, Triamtereen, Triamteril, Turfa, Uniretic

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Also known as: Amiloride

Description

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Amiloride is a potassium sparing-diuretic that also prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.

The combination of hydrochlorothiazide and amiloride is used to treat fluid retention (edema) and high blood pressure (hypertension).

Dosage

Take Acesistem by mouth with food. Acesistem may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm. If you want to achieve most effective results do not stop taking Acesistem suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Do not freeze. Keep container closed tightly. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acesistem are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Drinking alcohol can increase certain side effects of hydrochlorothiazide and amiloride.

Do not use salt substitutes or low-sodium milk products that contain potassium. These products could cause your potassium levels to get too high while you are taking Acesistem 5-50.

Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

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