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Acnex (Methylprednisolone)

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Acnex works well to control allergic reactions and conditions involving an overactive immune system. It can quickly make you feel better, but it might also cause side effects if you use it for a long time.

Other names for this medication:
Acnex, Avpred, Cartipred, Hysone, Meprolone, Methylprednisolone, Predon, Prelonb, Sterid, Zempred, Zencort

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Starlix, Caverta, Arava, Zudena, Levlen, Estrace, Bactrim, Skelaxin, Levitra, Zenegra, Direc, Melwin, Niftene, Liparon, Famtrex, Flagemed, Spentoin,

Also known as: Methylprednisolone


Methylprednisolone injection provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, arthritis, asthma, blood or bone marrow problems, eye or vision problems, lupus, skin conditions, kidney problems, ulcerative colitis, and flare-ups of multiple sclerosis. Methylprednisolone is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.

This medicine is to be given only by or under the direct supervision of your doctor.


Depo-Acnex is injected into a muscle or soft tissue, into a skin lesion, into the space around a joint, or given as an infusion into a vein. A healthcare provider will give you this injection.

Steroid medication can weaken your immune system, making it easier for you to get an infection. Call your doctor if you have any signs of infection (fever, chills, body aches).

If you have major surgery or a severe injury or infection, your Depo-Acnex dose needs may change. Make sure any doctor caring for you knows you are using this medicine.

If you use this medicine long-term, you may need medical tests and vision exams.

Detailed Depo-Acnex dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of methylprednisolone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Acnex dosage information

Side effects

The most common side effects associated with Acnex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Acnex if you are allergic to it, or if you have:

a fungal infection anywhere in your body.

Acnex can weaken your immune system, making it easier for you to get an infection. Steroids can also worsen an infection you already have, or reactivate an infection you recently had. Tell your doctor about any illness or infection you have had within the past several weeks.

To make sure Acnex is safe for you, tell your doctor if you have ever had:

a thyroid disorder; herpes infection of the eyes; stomach ulcers, ulcerative colitis, or diverticulitis; depression, mental illness, or psychosis; liver disease (especially cirrhosis); high blood pressure; osteoporosis; a muscle disorder such as myasthenia gravis; or multiple sclerosis.

Also tell your doctor if you have diabetes. Steroid medicines may increase the glucose (sugar) levels in your blood or urine. You may also need to adjust the dose of your diabetes medications.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether methylprednisolone passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

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