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Adalat (Nifedipine)
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Adalat

Adalat is a drug that performs by relaxing the muscles inside the heart and blood vessels in order to enable easier blood flow. This enables the heart to have an easier time pumping blood. The active ingredient is nifedipine and it a part of a class of drugs called calcium channel blockers. The primary use of this medication is to help stop chest pain (angina) and help treat high blood pressure problems (hypertension). In addition to this it can also be used in order to heighten the supply of oxygen and blood to the heart and help with a specific blood circulation condition called Raynaud’s phenomenon.

Other names for this medication:
Addos, Adefin, Adipine, Amarkor, Antrolin, Aprical, Atanaal, Atenerate, Bresben, Buconif, Calchan, Calcheck, Cardules, Cobalat, Conetrin, Cordipin, Corotrend, Fenamon, Fenidina, Glopir, Hexadilat, Hypan, Lemar, Marivolon, Menoprizin, Nifangin, Nifecap, Nifecard, Nifecor, Nifed, Nifedalat, Nifediac, Nifedipina, Nifedipine, Nifedipress, Nifelong, Nifezzard, Nilol, Nipidin, Nipin, Nipress, Noviken, Ospocard, Xepalat

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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adalat OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Adalat and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Adalat are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Identification of cyclophilin A from human decidual and placental tissue in the first trimester of pregnancy. The features of void denuded zones (VDZs) and the unusual behavior of void formation near GBs/interfaces in metals due to the interactions between GBs/interfaces and irradiation-produced point defects are systematically reviewed. Molecular genetic and transgenic studies have begun to implicate some of the genes encoding components of the renin-angiotensin system in the development of cardiovascular diseases. The taurine efflux, activated by cell swelling, is dramatically reduced when the phospholipase A2 is inhibited indirectly by addition of the anti-calmodulin drug pimozide, or directly by addition of RO 31-4639. Hydroxyurea was continued for two more years and the lesions worsened. In this double-blind crossover study, 38 patients with gastro-oesophageal reflux disease (GERD) symptoms were randomized to esomeprazole 40 and 20 mg and omeprazole 20 mg once daily for 5 days. No prospective studies were identified, and no studies reported on ethical approval or patient informed consent for the innovative procedure. The experimental results show that an appropriate value of the regularization parameter is easy to find without using costly cross validation, and the proposed TPCLR1 offers an efficient procedure to construct sparse RBFNN classifiers with good generalization performance. The units had cutaneous receptive fields which ranged in size from those restricted to one digit to those extending over the whole forelimb. Intraspecific variation in retinal cone distribution in the bluefin killifish, Lucania goodei.

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Feline SCF shows a high degree of homology to the SCFs of other species at both the nucleic acid and protein level. Expanding treatment options for stress urinary incontinence in women. Thalidomide at lower doses (1-20 mg/kg) also potentiated the antitumour effect. Enkephalins: Endogenous Analgesics with an Emerging Role in Stress Resilience. SIRT1 levels were observed to be increased in stage III-IV when compared with stage I-II breast cancer. The multidimensional imaging approach, which has been used in this particularly case, provided an excellent visualization and clinical evaluation of this rare finding. In continuing our search for selective alpha(1)-adrenoceptor (AR) antagonists, we have synthesized new alkoxyarylpiperazinylalkylpyridazinone derivatives. Coronary mortality and its prediction in samples of US and Italian railroad employees in 25 years within the Seven Countries Study of cardiovascular diseases. Moreover, 28-day mortality does not appear to be associated with the use of guidelines in this patient group. None of the three diagnoses showed any significant association with hypertensive diseases.

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We found that the expression of Delta FGFR4a in retinal progenitor cells results in abnormal retinal development. The unique manner in which Bcl-2 adjusted COX subunits during these physiological stress triggers had a profound impact on the resultant decrease in COX activity and maintenance of mitochondrial ROS levels, thus delineating a novel mechanism for the homeostatic role of Bcl-2 in the redox biology and metabolism of cancer cells. During population genetic studies in Korea a new variant in the 6-phosphogluconate (6-PGD) system preliminary called 6-PGDKorea was observed. Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement. There would seem to be little justification for the use of lipoprotein electrophoresis in screening the general population for coronary heart disease. Auditory brainstem response (ABR) and effects of furosemide on ABR in conscious F344 rats. The normal range of IgG subclass concentrations in children and adults is compared with deficiencies found in individuals with repeated respiratory tract infections. In order to improve the energy dissipation of the masonry infilled frame structure while decreasing the stiffening and strengthening effects of the infill panels, a new dry stacked panel (DSP) semi-interlocking masonry (SIM) infill panel has been developed. Currently the focus of attention is on the nucleotide-binding oligomerization domain (NOD)-like receptors (NLR), which take part in the regulation of the synthesis and maturation of cytokines in the IL-1 families, NOD-signalosomes and inflammasomes. Accounting of greenhouse gas (GHG) emissions from waste landfilling is summarized with the focus on processes and technical data for a number of different landfilling technologies: open dump (which was included as the worst-case-scenario), conventional landfills with flares and with energy recovery, and landfills receiving low-organic-carbon waste.

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Studies with highly purified preparations of the isofunctional DKCMOs confirmed the potential of the various reductases to function effectively as sources of the requisite FMNH2 to both monooxygenases at different times throughout growth on camphor. We present here a simple unsupervised learning dynamics that produces such a synaptic matrix if sequences of stimuli are repeatedly presented to the network at fixed order. Consultant pharmacists reviewed pharmacy records and medical charts from long-term care facilities, identifying older patients with a diagnosis of hypertension who either took CCB concomitantly with an ACE inhibitor or experienced adverse events on high-dose CCB therapy. These effects are more likely due to absorption of the intact flavonoid. An investigation of how electron/photon beam exposures affect the intercalation rate of Na deposited on graphene prepared on Si-face SiC is presented. The 3MPCA model can be estimated by the TUCKALS3 algorithm, which is an alternating least squares algorithm. Scintigraphic observations during the course of healing of bone fractures. To assess the outcome of a surgical punctal occlusion technique. A cycle of five weekly hyaluronic acid injections performed immediately following arthrocentesis is effective to improve signs and symptoms in patients with painful temporomandibular joint disc displacement with reduction and to maintain them over a 3-month follow-up.

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Heart rate (HR), breathing pattern, galvanic skin response (GSR), and electromyogram (EMG) of the frontalis muscle were measured in 39 male and female subjects aged 18-25 years during 10-minute treatment with relaxation technique (autogenic training and/or music) followed by 10 minutes of imagery training. The decision to remove a cilium surgically is controversial and must be based on the individual clinical examination. A comprehensive and systematic search was conducted with PubMed databases. Coronary heart disease (CHD) is still the main cause of death in developed countries. The Flp double cross system a simple efficient procedure for cloning DNA fragments.

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We consider work from multiple groups supporting this form of scaling, which we call neurotransmission-based scaling. Comparison between fat intake assessed by a 3-day food record and phospholipid fatty acid composition of red blood cells: results from the Monitoring of Cardiovascular Disease-Lille Study. Oxygen radicals in the nonvagal component of noncholinergic airway constriction. All cases were successful, with no residual fistula flow ultram 50 mg dosage , mortality, or morbidity. Coronary malperfusion due to type A aortic dissection is a life-threatening condition where timely recognition and treatment are mandatory.

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Lichen planus arising in an inflammatory linear verrucous epidermal nevus. Analysis of a repressor region in the human neuropeptide Y gene that binds Oct-1 and Pbx-1 in GT1-7 neurons. The porosity is directly influenced by particle size and particle-size distribution of the raw material. In the presence of the variant R551, SHP-1/2 activation is reduced and signal transduction is altered. The median recovery time is approximately 13 h after irradiation at any time during G1, but is markedly shorter (5-7 h) after irradiation in S or G2. Vasopressin increased aggressive vocalizations directed toward potential food recipients in all classes of caregivers. The reduced-diameter ITI dental implant might benefit from reinforcement of this region. Serum samples were assayed on-site before and at varying intervals after removing the tube stopper on an AVL OPTI Critical care Analyzer using E-Cl cuvettes. Collagen remodelling mainly as a result of an increase in collagen type III in the perimysium and perivascular region, occurs in the hearts of patients with diabetes.

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