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Aldara (Imiquimod)

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Aldara is a prescription medicine approved by the U.S. Food and Drug Administration (FDA). It is a cream for topical use only. Aldara is FDA-approved for the treatment of certain skin conditions.

Other names for this medication:
Imiquimod, Nilwart, Zyclara

Similar Products:
Altace, Bactrim, Calan, Allegra, Dulcolax, Cetag, Grelet, Plagril, Vardenafil, Montina, Noplaq, Gapen,

Also known as: Imiquimod


Aldara (imiquimod) is an immune response modifier. Aldara is used to treat actinic keratosis (a condition caused by too much sun exposure) on the face and scalp.

Aldara (for the skin) is also used to treat a minor form of skin cancer called superficial basal cell carcinoma, when surgery would not be an appropriate treatment.

Aldara also treats genital warts that appear on the outside of the body, but this medicine is not a cure for genital warts. Imiquimod may be used in adults and children who are at least 12 years.


This section provides information on the proper use of a number of products that contain imiquimod. It may not be specific to Aldara. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, vagina, or anus. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

This medicine comes with a patient information leaflet. Read and follow the instructions in the leaflet carefully. Ask your doctor if you have any questions.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

If you are using the Zyclara® cream pump for the first time, prime it by pressing the top of the pump until the cream appears.

To use the cream:

Wash your hands with soap and water before and after using the medicine. Use one or two packets or actuations of the pump of cream for each dose as directed by your doctor. Apply a thin layer to the affected area of the skin just before bedtime. Rub it in gently. Allow the medicine to stay on the treated skin for 8 hours (for actinic keratosis or basal cell carcinoma) or 6 to 10 hours (for genital warts). Do not take a bath, swim, or get the treated area wet during this time. After the right amount of time has passed, wash the treated area with mild soap and water. Men who are not circumcised and are treating genital warts under the foreskin should retract the foreskin and clean the area daily. Do not bandage or otherwise wrap the skin being treated, unless directed to do so by your doctor. Materials that are not airtight, such as cotton gauze or cotton underwear, may be used if needed. Throw out any unused cream from the single-dose packet.

Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

Do not use this medicine together with any other products containing imiquimod in the same treatment area. This may increase risk for more serious side effects.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (cream): For actinic keratosis: Adults—If you use Zyclara®, apply a thin film to the affected area of skin once a day at bedtime for 2 weeks. Your doctor will repeat the treatment after you go 2 weeks without medicine. If you use Aldara®, apply a thin film to the affected area of skin once a day at bedtime 2 times per week for 16 weeks. Your doctor will tell you which days are best during the week. Children—Use and dose must be determined by your doctor. For skin cancer: Adults—Apply a thin film to the affected area of skin once a day at bedtime 5 times per week for 6 weeks. Your doctor will tell you which days are best during the week. Children—Use and dose must be determined by your doctor. For external warts: Adults and children 12 years of age and older—If you use Zyclara®, apply a thin film to the wart once a day at bedtime for up to 8 weeks or until the wart is gone. If you use Aldara®, apply a thin film to the wart once a day at bedtime 3 times per week. Your doctor will tell you which days are best during the week. Use the medicine until the wart is gone, but for no longer than 16 weeks. Children younger than 12 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe skin irritation, feeling light-headed, or fainting.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the Zyclara® cream pump upright.

Detailed Aldara dosage information

Side effects

The most common side effects associated with Aldara are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of imiquimod topical for external warts in children older than 12 years of age. However, safety and efficacy have not been established in children younger than 12 years of age.

Appropriate studies on the relationship of age to the effects of imiquimod topical for actinic keratosis or skin cancer have not been performed in the pediatric population. Safety and efficacy have not been established.

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The isolation and characterization of a mucopolysaccharide secreted by the snail, Otella lactea. Upper gastrointestinal endoscopy revealed a marked antral nodularity but no evidence of bleeding lesions in all the patients. A biplanar radiographic technique was used to assess vertebral motion both before and after removal of Harrington rods in five patients. Although only small amounts of HIV-1 virions were released from Cav-1-transfected cells, these were fully infectious. Retrospectively we reviewed the clinical, radiological and pathological characteristics of 64 patients with a history of breast cancer resection who subsequently underwent surgical resection of an indeterminate SPN in our institute.

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Teaching Quality Improvement and Patient Safety in Residency Education: Strategies for Meaningful Resident Quality and Safety Initiatives. The effect of intrathecal fentanyl on Cerebral State Index-guided sedation during spinal anaesthesia. Hexabrix, therefore, appears to be the safest contrast agent where leakage into the pleural space may be suspected. The working mechanism can be ascribed to the piezoelectric-enzymatic-reaction coupling effect of enzyme/ZnO nanowires. Treatment goals may include enhancing family communication and addressing issues of loss. We have examined the dynamics of yolk steroid hormones during embryonic development in the snapping turtle, Chelydra serpentina, and the alligator, Alligator mississippiensis, and have found that yolk estradiol (E(2)) responds differentially to incubation temperature in both of these reptiles. It was found that six of eight imported seaweed products had concentrations of mercury orders of magnitude higher than the local products. Characterization of papillomavirus E1 helicase mutants defective for interaction with the SUMO-conjugating enzyme Ubc9. Transtracheal lidocaine ensured patient immobility with hemodynamic stability during total parotidectomy with nerve stimulation studies as compared to intraoperative dexmedetomidine infusion. In this study, we use electrical stimulation to investigate whether architectural changes in tibialis anterior (TA), a key muscle for balance and gait, affect the amplitude of surface EMGs.

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Distribution of growth factors in subfoveal neovascular membranes in age-related macular degeneration and presumed ocular histoplasmosis syndrome. Early endoscopic treatment of intramural hematoma of the esophagus. Routine analysis of hydrocarbons, PCB and PAH in marine sediments using supercritical CO2 extraction. Practical modalities and current possibilities of the diagnostic use of ultrasonics. This laccase inhibited proliferation of murine leukemia cell line L1210 and human hepatoma cell line HepG2, and reduced the activity of HIV-1 reverse transcriptase with an IC50 of 22 microM. The stimulation of immunity and the induction of unresponsiveness to Trichuris muris in various strains of laboratory mice. Discoid lupus erythematosus and cicatrizing conjunctivitis: clinicopathologic study of two cases. Childhood victimization and subsequent risk for promiscuity, prostitution, and teenage pregnancy: a prospective study. It was shown experimentally that SjAg immobilized by the Cys-PSS adsorption procedure had higher immunological activity or binding efficiency than those immobilized by the glutaraldehyde (GLU) binding or direct attachment procedures. Activation of the eukaryotic initiation factor 2alpha (eIF2alpha) kinase general control nonderepressible-2 (GCN2) following tryptophan depletion is a major pathway mediating this effect.

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Deracemization of alpha-methylbenzylamine using an enzyme obtained by in vitro evolution. Decision making in the surgical treatment of cervical spine metastases. International trends in mortality rates for bronchitis, emphysema and asthma during the period 1971-1980. This study examined the factors that influenced or determined utilization of healthcare facility delivery services among women who attended antenatal care (ANC) services. Predicting thyroid nodule malignancy at several prevalence values with a combined Bethesda-molecular test. Therefore, free perforator flaps are playing increasing role in reconstruction of complex scar contractures. The inhibitory neurotransmitter glycine is a co-agonist of NMDA receptors and functional glycinergic co-activation of NMDA receptors is theoretically possible due to the presence of background glutamate. Furthermore, there were no significant differences in laxities such as PTT, external rotation, or varus rotation between the SB and DB PCL reconstruction groups. Of clinical importance is the frequent occurrence of hypoglycaemia for which several risk factors are recognized.

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capsulatum infection (25 in AIDS patients) and 17 cases of Histoplasma capsulatum var. The histopathological differential diagnosis of respiratory epithelial adenomatoid hamartomas includes inverted papilloma and adenocarcinoma. The expression of caveolin-1 was positively correlated with an advanced pathologic stage. The diagnosis of an urinary tract infection (UTI) is proved by the identification of a significant leucocyturia and bacteriuria of the mid-stream urine analysis in men and catheter urine in women. Six cases are presented, all evaluated with sonography, Color-Doppler US, Spiral CT and Magnetic Resonance Imaging side effects of effexor and alcohol (MRI).

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