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Aldbest (Montelukast)
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Aldbest

Aldbest is a leukotriene (loo-koe-TRY-een) inhibitor that is used to prevent asthma attacks in adults and children at least 2 years old. Aldbest is also used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs) in adults and children who are at least 6 years old.

Other names for this medication:
Admont, Aldbest, Celkast, Deriphyllin, Ebast, Ferodr, Fexokast, Fexoquin, Imont, Irmont, Jotair, Kurecet, Leomont, Levoler, Levosiz, Levotin, Lewlet, Lezest, Lupimon, Monkezin, Montair, Montal, Montas, Monteleo, Monten, Montilife, Montolife, Pulmokast, Reakst, Reokast, Rhinomont, Riokast, Sanmonte, Tastymont, Trimontemac, Tykast, Ventyl, Xyzal

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Also known as: Montelukast

Description

Aldbest tablets, produced by Merck Sharp & Dohme, are indicated in the treatment of asthma as add-on therapy in those patients with mild to moderate persistent asthma who are inadequately controlled on inhaled corticosteroids. It helps prevent the wheezing, chest tightness, and shortness of breath caused by asthma and decreases the number of asthma attacks. The medicine is used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs). It also helps treat seasonal and perennial allergic rhinitis. The active substance contained in the medication is Montelukast, a leukotriene receptor antagonist, that stops leukotrienes, chemical messengers in the immune system, from causing inflammation in the lungs and nose, preventing asthma symptoms and allergies.

Dosage

Usual Adult Dose of Aldbest for Allergic Rhinitis:

-10 mg orally once a day Comments: -For asthma, efficacy has been demonstrated when this drug was administered in the EVENING without regard to time of food ingestion. -For allergic rhinitis, efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. Uses: -Prophylaxis and chronic treatment of asthma -Relief of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis

Usual Adult Dose of Aldbest for Asthma -- Maintenance:

-10 mg orally once a day Comments: -For asthma, efficacy has been demonstrated when this drug was administered in the EVENING without regard to time of food ingestion. -For allergic rhinitis, efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. Uses: -Prophylaxis and chronic treatment of asthma -Relief of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis

Usual Adult Dose for Bronchospasm Prophylaxis:

-10 mg orally once a day at least 2 hours before exercise Comments: -An additional dose should not be taken within 24 hours of a previous dose. -Patients already taking this drug daily for another indication (including chronic asthma) should not take an additional dose to prevent EIB. -A rescue short-acting beta-agonist should be available at all times. -Daily administration for the chronic treatment of asthma has not been established to prevent acute episodes of EIB. Use: Prevention of exercise-induced bronchoconstriction (EIB)

Usual Pediatric Dose of Aldbest for Asthma -- Maintenance:

Less than 12 months: Not approved. 12 to 23 months: -One sachet of 4 mg oral granules once a day 2 to 5 years: -4 mg chewable tablet or one sachet oral granules once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Doses should be taken in the evening. -Efficacy has been demonstrated for asthma when this drug was administered in the evening without regard to time of food ingestion. Use: Prophylaxis and chronic treatment of asthma in pediatric patients 12 months of age and older

Usual Pediatric Dose of Aldbest for Allergic Rhinitis:

Seasonal Allergic Rhinitis: Less than 2 years: Not approved. 2 to 5 years: -4 mg chewable tablet or one sachet of 4 mg oral granules once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Perennial Allergic Rhinitis: Less than 6 months: Not approved. 6 to 23 months: -One sachet of 4 mg oral granules once a day 2 to 5 years: -4 mg chewable tablet orally once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -The time of administration may be individualized to suit patient needs. Uses: -Relief of symptoms of seasonal allergic rhinitis in patients 2 years of age and older -Relief of symptoms of perennial allergic rhinitis in patients 6 months of age and older

Usual Pediatric Dose for Bronchospasm Prophylaxis:

Less than 6 years: Not approved. 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Dose should be taken at least 2 hours before exercise. -An additional dose should not be taken within 24 hours of a previous dose. -Patients already taking this drug daily for another indication (including chronic asthma) should not take an additional dose to prevent EIB. -A rescue short-acting beta-agonist should be available at all times. -Daily administration for the chronic treatment of asthma has not been established to prevent acute episodes of EIB. Use: Prevention of exercise-induced bronchoconstriction (EIB) in patients 6 years of age and older

Detailed Aldbest dosage information

Overdose

If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Keep your tablets in the blister pack until it is time to take them. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aldbest are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid situations or activities that may trigger an asthma attack.

If your asthma symptoms get worse when you take aspirin, avoid taking aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

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Periprosthetic infection of a total knee arthroplasty (TKA) can be successfully eradicated by two-stage resection arthroplasty. Participant nurses believed safety could be improved in each one of the scenarios. Rats were administered saline, VP (50 ng), or amphetamine (1 mg/kg or 3 mg/kg) on days 1 and 2, and given saline or amphetamine on day 3. Structural characterization and biological properties of human gastrokine 1. Innovative formulations such as fumigant canister and insecticidal paints have been successfully developed in Latinoamerica with the World Health Organization support. The HSP-immunostaining in neurons of the T9 and T12 segments of the spinal cord was virtually lacking in the drug treated animals. Our experimental data allow understanding forces that affect the structure of a protein functioning near the membrane surface (in other words, in the membrane field). Quantitating plant microRNA-mediated target repression using a dual-luciferase transient expression system. The methylenedioxy analogues were 36- to 180-fold more potent than the parent camptothecin, possessing IC50 values ranging from 160 to 32 nM against the parasite. After 100 days, LPS was used to induce arthritis, and the severity of arthritis was evaluated.

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We plan to acquire data from pigs used by surgeons for training purposes, but conceivably, the tools could be refined for use on humans undergoing surgery. Recently, cases were reported that influenza virus becoming resistant to oseltamivir, necessitating the development of new long-acting antiviral compounds. Allelotyping of anaplastic thyroid carcinoma: frequent allelic losses on 1q, 9p, 11, 17, 19p, and 22q. During the second half of stance, the keel provided decreased propulsion and increased support. Analysis of butadiene, butadiene monoxide, and butadiene dioxide in blood by gas chromatography/gas chromatography/mass spectroscopy. Partial versus complete caval interruption for venous thromboembolism.

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Discoid lupus erythematosus is a manifestation of chronic cutaneous lupus erythematosus with a small risk of systemic involvement. For women in prolonged labor, obstetric intervention can be an acceptable or even favorable option. Careful wound care and localization of severed nerves and ducts, and repair under microscope are emphasized. Spectrophotometry of opaque biological materials--reflection methods. The chemically modified peptides containing each of the three Tyr residues present in the RARalpha-LBD sequence were then analyzed and identified by high-performance liquid chromatography coupled to electrospray ionization mass spectrometry (HPLC/ESI-MS). The latter fraction corresponded to a fast-moving component on electrophoresis in Cellogel and seems to be identical with a slowly moving isoenzyme in starch and polyacrylamide gel electrophoresis. The number of pregnancies and other hormonally related factors were recorded. The phenomenon of transient or persistent dysmaturity following NB seizures will be discussed in relation to etiological factors. These hydrogels may aid the development of adhesive tissue engineering matrixes, wound dressings, sealants, and the adhesive components of biomedical devices.

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Chronological effects of atherogenic diets on the aorta, liver and spleen of rabbits. Case reports and small case series: primary basal cell carcinoma of the conjunctiva with intraocular invasion. The mutual information between pairs of maps serves to partition the data set in clusters, without prior assumptions about the structure of the underlying distribution of the data. Both endogenous vitamin E in the membranes and a water soluble vitamin E analogue added simultaneously with a radical initiator suppressed the hepatic damage. Recent reports showed that exercise training (ET) improves the exercise capacity of these patients. Antral regulation of the intestinal secretion phase of the stomach. We report a case of rheumatoid vasculitis in a 48 years old women with long history of RA, who developed vasculitis of distal arteries with gangrene of digits of upper and lower extremities. ON THE EFFECT OF A NEW CYTOSTATIC (RO-4-6467) ON THE INCORPORATION OF LABELLED GLYCINE IN TUMOR CELLS. A dose-effect relationship could be established for quinidine with regard to the inhibitory effect on CYP2D6 norvasc dosage increase activity.

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