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Allerde (Desloratadine)
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Allerde

Allerde is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Allerde is used to provide symptomatic relieve of allergic symptoms. Allerde diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle.

Other names for this medication:
Alerdain, Alerta, Allerdain, Allerde, Allerede, Allergesic, Antialer, Biomon, Dazit, Delorta, Descare, Desent, Deslor, Desloranid, Desloratadine, Desloriv, Desnova, Dilora, Lorday, Loreta, Nelora, Neoloridin, Nucope, Otrivin, Reditabs, Rodera, Tastylora, Veromon

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Microzide, Diamox, Atarax, Symmetrel, Anafranil, Acticin, Protonix, Movacam, Maturova, Anabrez, Liperial, Goldep,

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Also known as: Desloratadine

Description

Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Dosage

Usual Adult Dose for Allergic Rhinitis:

5 mg orally once a day Uses: -Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis -Relief of nasal and non-nasal symptoms of perennial allergic rhinitis -Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria

Usual Adult Dose for Urticaria:

5 mg orally once a day Uses: -Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis -Relief of nasal and non-nasal symptoms of perennial allergic rhinitis -Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria

Usual Pediatric Dose for Allergic Rhinitis:

6 to 11 months: 1 mg orally once a day 12 months to 5 years: 1.25 mg orally once a day 6 to 11 years: 2.5 mg orally once a day 12 years and older: 5 mg orally once a day Uses: -Patients 6 months and older: Relief of nasal and non-nasal symptoms of perennial allergic rhinitis -Patients 6 months and older: Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria -Patients 2 years and older: Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis

Usual Pediatric Dose for Urticaria:

6 to 11 months: 1 mg orally once a day 12 months to 5 years: 1.25 mg orally once a day 6 to 11 years: 2.5 mg orally once a day 12 years and older: 5 mg orally once a day Uses: -Patients 6 months and older: Relief of nasal and non-nasal symptoms of perennial allergic rhinitis -Patients 6 months and older: Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria -Patients 2 years and older: Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis

Detailed Allerde dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose may cause anxiety, trouble sleeping, headache, vomiting, thirst, muscle weakness, fast or pounding heartbeats, hallucinations, shallow breathing, or a seizure.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Desloratadine/pseudoephedrine dosage information

Side effects

The most common side effects associated with Allerde are:

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Contraindications

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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However, the degree of ecological generalization and of dependence on pollinators varies greatly among species of both flower symmetry types and this may also affect flower size variation. This implies that (i) the rigid docking can be used as a tool for qualitative prediction of activity and (ii) values obtained by the rigid docking technique into the cdk2 active site can also be used for the prediction of cdk1 activity. Immediate operative decompression proved to resolve the acutely evolved symptoms in all 3 cases. Conservative treatment remains a good option for patients with incomplete cervical cord injuries. We find that resting gamma delta T cells are characterized by an inflammatory migration program similar to cells of the innate immune system. Sixty-one consecutive episodes of SBP were studied in patients with end-stage liver disease undergoing evaluation for liver transplantation between 1991 and 2001. Four of the authors measured the QT interval in all ECGs using a previously developed approach. Although the erythrocyte sedimentation rate is frequently elevated there is no other evidence of co-existing systemic disease. Hydroxyurea and radiation therapy in advanced neoplasms of the head and neck. Confounding variables affecting in vitro fertilization success: a decade of experience.

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Spirometric reference values for white European children and adolescents: Polgar revisited. Five patients with a wide range of prostate volumes and treated with primary external beam radiation therapy for localized prostate cancer were selected for analysis. No bacterial aggregates were identified in any histological samples, nor any sign of tissue necrosis identified. Thirty-three noninstitutionalized, active middle-class pensioners (mean age 68 years) tenormin tab 50mg assessed their own life curve as resembling a shallow rainbow, the age periods between 30-50 years being most highly valued. The authors showed for the first time that the knockdown of SPAG9 expression by small interfering RNA significantly suppressed the tumor growth of cervical SCC in vivo.

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On the first day, measurements were also performed in the afternoon. These perspectives need to be integrated with patient and community perspectives. Otoacoustic emissions in patients with retrocochlear dysfunction: a report of five cases. The results presented indicate that significant relationships are indeed found among phenomena involving damage to or modification of DNA but not between them and non-genotoxic phenomena. Construction of an internal standard for semiquantitative polymerase chain reaction analysis of heat shock proteins. These guidelines are based more on clinical experience than on scientific evidence. Toxicity, especially myelosuppression and pneumonitis, was more pronounced in the elderly patients receiving combined-modality therapy for locally advanced NSCLC.

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Patients were examined whenever they developed vaginal symptoms and were treated on the basis of microscopic and culture results. The aim of this study was to evaluate the craniofacial characteristics of patients with heart disease. Neuropathological observation of rabbits (Oryctolagus cuniculus) affected with raccoon cost of detrol la 4mg roundworm (Baylisascaris procyonis) larva migrans in Japan. It is important to note that two groups had different characteristics in age distribution, frequency of trauma history, symptom duration, lesion size and location, and incidence of degenerative changes. The common fruit fly, Drosophila melanogaster, has been used to study human disease as a model organism for many years. This study explores sociocultural differences in alcohol-related impact on quality of life between France and United Kingdom. On the other hand, although the secretory activity of Gn was markedly decreased during hibernation, a stimulatory effect of GnRH on Gn secretion was observed. Grade, tumor size, and RMS grouping of the tumors were found to be of prognostic value.

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