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Alpram (Alprazolam)

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Alpram is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpram, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpram is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alamflu, Alfix, Alpkair, Alpracon, Alprazan, Alprop, Alprozam, Alzin, Ambulax, Ambutech, Anxicalm, Anxilam, Anxyl, Avizolem, Benzolam, Censir, Enxolam, Exprex, Finezol, Fluzolam, Luzarn, Nexlpra, Omelam, Pranol, Selam, Setex, Somaspas, Suzilam, Wycalm, Xylonite, Zopic, Zopral

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Xanax, Strattera, Urispas, Colcrys, Coumadin, Trandate, Parlodel, Feldene, Ovral, Duphaston, Flucozen, Fluotec, Ceton, Acudep, Lipium, Lactone, Lobibeta, Balmusa,

Also known as: Alprazolam


Alpram is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alpram is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alpram if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alpram or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alpram. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpram XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpram XR dosage information

Side effects

The most common side effects associated with Alpram are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Mechanisms underlying the effects of remote noxious stimulation and mental activities on exteroceptive jaw reflexes in man. Information on mercury and selenium molar relation in muscle, liver and kidney tissue of Greenland marine animals is presented. Trends in food consumption show increases in intakes of meat, dairy products, fish, and fruit, but decreases in consumption of olive oil, sugar, and all foods rich in carbohydrates. Yeast-derived HBeAg exhibits high HBe antigenicity while lacking any HBc antigenicity. Chlamydia caviae infection had a profound effect on the absolute abundance of bacterial phylotypes but not on the composition of the guinea pig vaginal microbiota.

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Unexpectedly, genes considered exclusively non-neuronal also contained an RE1 motif and were expressed in neurons. Role of Transcatheter Intra-arterial Therapies for Hepatocellular Carcinoma. Seasonal differences in the probability of males presenting as trauma cases suggest behavioral factors as an important risk factor for this group. These observations are discussed in relation to the problem of protein turnover, and are interpreted as evidence for the de novo synthesis of alpha-amylase in this organism. After 30 days, three-point bending test was done in a dental arch model and data from selected points on the unloading phase of the generated graphs were used for statistical analysis. Athletes also reported greater levels of enhancement motives for sex and lower levels of intimacy motives than nonathletes, although no differences were found for coping motives.

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The significance of change in oxygen consumption in artificial blood circulation in experimental conditions. Immunohistochemical studies have revealed that high microvessel density (MVD) was associated with poor prognosis in carcinomas of the uterine cervix, endometrium, vulva and ovary. Males reared under different light regimes showed a significant correlation between the length of light and sexual maturation. Histological findings after temporal lobectomy confirmed hippocampal sclerosis but also revealed sequelae of a focal encephalitis and microdysgenesis of the hippocampus. In this study we compare six different assays for the evaluation of immunotoxins: protein and DNA synthesis inhibition assay, chromium release assay, cell line colony assay, limiting dilution assay and clonogenic assay. Therefore, the activity is not dependent on chiral interactions between the peptides and the lipid bilayers or the bacterial membranes. Global risk assessment for lipid therapy to prevent coronary heart disease.

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Locoregional control is associated with breast cancer-specific and overall survival in select women with breast cancer. Biodegradability of food-associated extracellular polysaccharides. Here, we report on an approach that significantly reduces the complexity, effort and time needed to express UAA-containing proteins while increasing stability and realizing maximal suppression efficiency. In spite of the numerous medical modalities employed in the management of oral submucous fibrosis, occasionally surgical intervention becomes inevitable. These cases illustrate that the symptoms of FTD in Chinese-Americans are similar to those in Caucasians but various factors, some potentially culturally relevant, may influence the likelihood and timing of clinical presentation for FTD, as well as other dementias. FHL should be included in the differential diagnosis of patchy white matter abnormalities in young patients. Effect of ionizing irradiation of low intensity on the viability of Escherichia coli bacteria, cultivated in the salt buffer. Maximum catalytic capacity for renal trehalase varied from 20 micromoles (of glucose produced per minute per gram of can you buy permethrin over the counter uk fresh tissue) for the armadillo down to zero for the rat, the cat, most turtles, fishes, and all birds and snakes investigated. Magnetic resonance imaging revealed a lesion in the midbrain surrounding the sylvian aqueduct in addition to bilateral masses in the caudate nuclei.

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Isolated multiple bilateral thyroid metastases from prostatic adenocarcinoma: case report and literature review. Velocardiofacial syndrome is associated with an increased incidence of immune cytopenias and, thus, warrants evaluation in any child with the clinical diagnosis of VCFS. Among the treatments reviewed here are surgical resection, orthotopic liver transplantation, and local ablative therapies such as cryosurgery, percutaneous ethanol injection therapy, and transarterial chemoembolization. Apoptosis was found to occur with storage in both irradiated and nonirradiated units. The PEGylated immunoliposome showed substantially higher cellular uptake than the PEGylated liposome in cancer cells (BT-474 and SK-BR-3) over-expressing human epidermal growth factor receptor 2 (HER2) at 37 degrees C, while no difference was found in low HER2 expressing cells (MDA-MB-231) nor at low temperature (4 degrees C). Multi-phase reaction systems, mostly aqueous organic systems, are used in enzyme catalysis to convert hydrophobic substrates which are almost insoluble in aqueous media. The manifestations of the disease were compared in 98 drug addicts and 100 patients stating they used no drugs. Protooncogenes are intimately involved in the processes of how many zyrtec pills should i take cell proliferation and differentiation.

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