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Alpronit (Alprazolam)

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Alpronit is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alpronit is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alpronit may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Almee, Alprasert, Alproz, Altin, Altrex, Alzac, Alzom, Alzot, Anxit, Anxitab, Anxorel, Anzilum, Ateez, Azoslip, Calmef, Dexolam, Fluxin, Himzolam, Mediprex, Nexlpra, Prozam, Prozolam, Restam, Rivcam, Samitol, Sanprazole, Serxanti, Somnarest, Somnirest, Tensfree, Xylonite, Zeecam, Zolipax, Zopam, Zopax

Similar Products:
Valtrex, Anafranil, Aristocort, Nexium, Retin, Primodil, Desloriv, Glymep, Cholvast, Ilozin, Ramin, Flomicet, Elgnil, Desent,

Also known as: Alprazolam


Alpronit XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alpronit XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alpronit XR may also be used for other purposes not listed in this medication guide.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpronit XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpronit dosage information

Side effects

The most common side effects associated with Alpronit are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Hexosamine biosynthesis impairs insulin action via a cholesterolgenic response. These results may indicate a global translational or protein homeostasis defect in cells simultaneously lacking mcm5 and s2 wobble uridine modification that could account for growth impairment and mainly originates from tRNA(Lys)UUU hypomodification and malfunction. MPTP-induced parkinsonism in mice alters striatal and nigral xCT expression but is unaffected by the genetic loss of xCT. However, Cre recombinase, by inducing DNA double-strand breaks (DSBs), can cause a reduced proliferation and genotoxic effects in cultured cells. Phosphorylation of P-glycoprotein induced by heat shock was not dependent on synthesis of new proteins, since phosphorylation was not inhibited by cycloheximide and the content of P-glycoprotein, as measured by immunoblotting, did not change after heat shock. A comparative study of five technologically diverse CFTR testing platforms. Activation of mouse oocytes requires multiple sperm factors but not sperm PLCgamma1.

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Biomechanical analyses of the maxillary expansion force system are concomitant with the holographic findings and strongly suggest that the stainless steel wires joining the teeth to any expansion device be of the largest diameter possible. After ischemia, protein levels of the SUMO-conjugating enzyme Ubc9 were transiently decreased in the cortex but not in the hippocampus. A double-blind, placebo-controlled pilot study was conducted whereby six patients received 0.1, 0.25, 0.5, 0.75, 1.0, or 1.5 mg etanercept intradiscally in each pain-generating disc. Moreover, none of the agents used to date are designed to act selectively upon the heart. Explants of pulmonary adenomas, induced in mice by urethan, were cultured with or without prednisolone for 72 hr. Plaque control: home remedies practiced in developing countries. The number of cancer clinical trials in Korea rapidly increased from 2007 to 2013, as has the number of multicenter clinical trials and IITs run by cooperative study groups. Although the administration frequency of ACEI and beta-blockers increased quickly, there had been a great gap between the optimal medical strategy and clinical practice in the management of CHF. Dietary therapy improved her malabsorption and the renal stones were cleared by extracorporeal shortwave lithotripsy. Tubulo-squamous polyp: a report of ten cases of a distinctive hitherto uncharacterized vaginal polyp.

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Reemergence of enterovirus 71 epidemic in northern Taiwan, 2012. Recent research has also shown that survival materials and processing result in more false memories, ones that are adaptive inasmuch as they prime solutions to insight-based problems. In this study, 19 children (8 girls and 11 boys) with LMC aged between 5 and 7years were matched by age and gender with 19 children with high motor competence (HMC). of experimental pigs during the period from birth to slaughter was 13 g higher in comparison to the controls. After Bonferroni correction the difference between groups was significant in the right caudate.

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The mechanism for CRF in enhancing REM sleep may be associated with but not be similar to the cholinergic mechanism. In total, this analysis suggests a functional architecture for K-Rev that is similar to, but distinct from, that described for HIV-1 Rev and raises the possibility that viral RNA export mediated by the approximately 25 million-year-old K-Rev protein may require an additional cellular cofactor that is not required for HIV-1 Rev function. CNKSR2 deletions: a novel cause of X-linked intellectual disability and seizures. Sun skink landscape genomics: assessing the roles of micro-evolutionary processes in shaping genetic and phenotypic diversity across a heterogeneous and fragmented landscape. No clinical symptoms could be detected at any time during or after treatment. This model is very similar to the default model of neural induction in the frog, thus bridging the evolutionary gap between amphibians and mammals.

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Murine monoclonal antibodies reactive with a human monoclonal anti-RhD antibody (BRAD-5). Parental psychopathology, parenting styles, and the risk of social phobia in offspring: a prospective-longitudinal community study. The position of each node respective to vascular anatomy was transferred to a standardized template. Theory provides a method for calculating the variability of replicate composite samples and applying it to individual units. These receptors fulfil the criteria postulated for the receptors of innate immunity and signalling from TLRs induces synthesis of various pro-inflammatory cytokines, enzymes and mediators. Cigarette smoking adversely affects culture conversion during anti-tuberculosis treatment. This Account outlines these new metal-catalyzed reactions that include couplings, cycloadditions, and cyclization reactions.

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Ureteral lesions caused by external trauma: diagnosis and treatment. The five case reports were spontaneous, other cases may not have been reported. Importance of the alanine methyl ester side chain for the biological activity profile of dual-function phenyl phosphate derivatives of bromo-methoxy-zidovudine. Discrimination of the guideline was quantified and the quality of decisions was evaluated by Net Benefit Fraction index considering the harm, for false-positive, and benefit, for true-positive predictions. On the specificity and diagnostic value of the Hakim reaction in malignant neoplasms. Intracrine role of progesterone in fibronectin production and deposition by chicken ovarian granulosa cells in vitro: effect of extracellular calcium.

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Bacteriologic and clinical efficacy of amoxicillin/clavulanate vs. In both Fischer and Lewis strains, major protein autoantigens were observed at 75-83, 68-71, 63, 57, 51, 41, and 21-23 kDa, lending support to the hypothesis that there is a set of dominant sperm autoantigens recognized by a consensus of postvasectomy rat sera. 3D FFE has better visibility for cartilage than VISTA and VISTA has superior visibility for TFCC to 3D FFE and the visibility for scapholunate ligament was best on VISTA. Here, we describe a novel transoral surgical technique for pyriform sinus fistula using transoral videolaryngoscopic surgery (TOVS) as a definitive treatment to resect and close the fistula without skin incision clobetasol propionate and salicylic acid ointment brand names . We successfully isolated DNA and RNA from the samples described above, and this material was suitable for PCR, methylation profiling, real-time PCR and DNA sequencing. PBDA 5, 50, and 100 mumol.L-1 concentration-dependently reduced the inward rectifier potassium current. In vivo efficacy studies show that EXEL-7647 substantially inhibited the growth of H1975 xenograft tumors and reduced both tumor EGFR signaling and tumor vessel density.

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Peritumoral injections of prostaglandin E2 (PGE2), leukotriene B4 (LTB4), and 12-hydroxyeicosatetraenoic acid (12-HETE) were performed for 16-21 days, and final excised tumor weights were measured. For patients treated with one-stent crossover LM to LAD, clinical outcomes appear cost of allegra d 24 hour similar between FKB and non-FKB strategy. ROENTGENOLOGIC VISUALIZATION OF THE STYLOHYOID LIGAMENT IN PATIENTS WITH RHEUMATOID ARTHRITIS. The author describes a delayed occlusion of the colon, consecutive to an ischemic constriction, occurring after a car accident in a patient wearing his safety belt. Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD.

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Air pollution particles diminish bacterial clearance in the primed lungs of mice. LINCing complex functions at the nuclear envelope: what the molecular architecture of the LINC complex can reveal about its function. The resulting defects were similar to the loss/gain-of-function phenotypes typical of tissue-polarity genes. Laparoscopic total pelvic exenteration for locally recurrent rectal cancer is a technically challenging procedure requiring a long operative time. An opportunistic sample of 82 nurses, was chosen from recent admission on a pre-registration degree programme, to mature graduates, as well as a group of experienced, non-graduate practitioners. In a 70-kg resident, a daily dose of 40 mg of furosemide was associated with an increase of 22.8 pg/mL in PTH, while 500 mg of elemental calcium carbonate ( bactrim 500 mg bid in the absence of a proton pump inhibitor) was associated with a decrease of 8.7 pg/mL in PTH. Organization and characterization of the keratin cytoskeleton in the previtellogenic ovarian follicle of the lizard Podarcis sicula raf. Semen characteristics and testicular morphology of rhesus monkeys were studied on exposure to a simulated high altitude of 4411 m for 21 days. The biochemical composition of these fractions has been established from the assay and distribution pattern of 22 enzymatic and chemical constituents including marker enzymes for mitochondria, lysosomes, peroxisomes, plasma membranes, endoplasmic reticulum, Golgi apparatus and cell sap.

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Screening system based on the interaction between E6AP and E6 may be a promising system in the development of drugs against cervical cancer caused by HPV infection. Endotoxin at concentrations of up to 5 micrograms/mL did not induce significant toxicity in any of the cells. Intravitreal bevacizumab versus verteporfin and intravitreal triamcinolone acetonide in patients with neovascular age-related macula degeneration. In the past 100 years intussusception has been treated by both surgical and nonsurgical methods. A 10-s delay impaired recall for primacy and middle list items but not recency. Screening strategies for neonatal hearing loss: which test is best?. The patients were randomly assigned to receive Healon5 or Viscoat during cataract surgery in the first eye. Spectral-ripple resolution correlates with speech reception in noise in cochlear implant users. The techniques of remote sensing (RS) and geodesy have the potential to revolutionize the discipline of epidemiology and its application in human health. An application on a published phylogeny of KRAB zinc finger genes is presented.

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We examined the relations of sedentary time and physical activity to mortality from any cause using accelerometry data among 1,677 women and men aged 50 years or older from the National Health and Nutrition Examination Survey (NHANES) 2003-2004 cycle with follow-up through December 31, 2006. Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains. It has been described how the potency and response time of local anaesthetics is improved (for clinical applications) when they are dissolved in a solution of sodium bicarbonate. Nutritional studies on a tick-borne encephalitis virus in amnion cell culture. The effect of selected vitamin B12 antagonists and other compounds on the C1300 mouse tumor. Third generation cephalosporin-resistant gram-negative bacilli in the feces of hospitalized children. Protein-energy malnutrition as a risk factor for increased morbidity in long-term hemodialysis patients. A FAMILIAL SYNDROME OF FACIAL AND SKELETAL ANOMALIES ASSOCIATED WITH GENITAL ABNORMALITY IN THE MALE AND NORAML GENITALS IN THE FEMALE: ANOTHER CAUSE OF MALE PSEUDOHERMAPHRODITISM. The statistical analysis was done using analysis of variance with repeated measures and paired t-test.

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