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Amimax

Amimax is a type of drug called a tricyclic antidepressant. Amimax works by increasing the amount of serotonin your brain makes. These drugs were originally developed to treat anxiety and depression, but when taken at a low dose they can reduce or stop pain.

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Also known as: Amitriptyline

Description

Amimax (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amimax is a prescription medicine used to treat symptoms of depression.

Dosage

Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amimax dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amimax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Amimax if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Amimax if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Amimax is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Amimax is not approved for use by anyone younger than 12 years old.

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Vascular effects of exercise training in CKD: current evidence and pathophysiological mechanisms. We previously reported that trigeminal rhythmic activities could be induced by some pharmacological applications in an isolated brainstem preparation with a rostral boundary at the border between the inferior and superior colliculus, and a caudal border at the level of the rostral facial nucleus. Flavonoids are effective antioxidants and may protect against several chronic diseases. A case of epithelial ingrowth primarily involving the lens capsule. alpha-MSH and desacetyl-alpha-MSH signaling through melanocortin receptors. This planning system has been tested and used at NASA-Johnson Space Center. Chronic cough is a multi-factorial symptom,postnasal drip syndrome (PNDS) and gastro-esophageal reflux disease (GERD) are common causes of chronic cough, which is closely associated with the otolaryngologist.

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To this end, in this study we have developed a series of semi-implicit predictor-corrector Brownian dynamics algorithms for bead-spring chain micromechanical model of polymers that utilizes either the Chebyshev or the Krylov framework. A Th2 shift was not detected, and the predominant presence of an IL-10-producing, immunosuppressive T helper cell subset could be excluded. Phase I dose escalation trial evaluating the pharmacokinetics, anti-human cytomegalovirus (HCMV) activity, and safety of 1263W94 in human immunodeficiency virus-infected men with asymptomatic HCMV shedding. Microbes and host response: A relationship between health and disease. Thrombosed arteriovenous malformations initially diagnosed as low-grade gliomas in a child and her maternal uncle are presented. Dirofilariasis involving Dirofilaria repens is an exceedingly rare event in France. A comparison of hearing-impaired students in Israel, Denmark, and the United States. The growth factors TGFbeta1 and FGF2 were expressed in the entire perichondrium immediately after explantation. Pituitary tumour transforming gene: a novel factor in pituitary tumour formation. It builds upon a zoomable grid display to represent two categorical dimensions.

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Histochemical characterization of non-neuroendocrine tumors and neuroendocrine cell hyperplasia induced in hamster lung by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone with or without hyperoxia. In the absence of well developed primary care health system in Pakistan, majority of patients present to psychiatrists as a first contact. Three monoclonal antibodies (MAbs) were generated from splenocytes of a BALB/c mouse immunized with heat-killed Mycobacterium tuberculosis. The choice of the treatment depends on the number of abscesses, their volume, and also the presence of extrasplenic involvement. However, the recent findings of UV-induced p53 mutations in advanced MF suggest that phototherapy may contribute to disease progression. To determine objective data to improve the methods of identification of the anterior ethmoidal artery during endoscopic dissection. It was concluded that adjuvant therapies targeting reg4 could improve the standard treatment of pancreatic cancer with gemcitabine. Status of the prostacyclin and thromboxane system, lipid metabolism and lipid peroxidation processes in patients with coronary atherosclerosis.

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Asymptomatic Papules and Subcutaneous Nodules as First Sign of Gout. Despite the presence of 18 genes within the cag pathogenicity island which are essential for this process, several homologues encoding basic functions of a type IV secretion apparatus, such as a virB8 homologue, are still missing. The evidence for such waves has been obtained recently by experiments and computations. In this issue, Schiaffini and colleagues confirm and extend published data describing the benefits of CGM in diabetic children. Patients with rostral medial tegmental lesions and controls with pontine base lesions showed unstable walking characterized by irregular angular displacements and foot pressures. Its aberrant expression has been observed in various tumor cells. Previous studies that employed site-specific protein-DNA photocrosslinking indicated that the conformation of the DNA-protein complex is different depending upon whether DM:PBP is bound to a U1 or U6 PSE sequence. Subunit composition and localization of a deubiquitylating enzyme.

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Cleavage of cartilage oligomeric matrix protein (thrombospondin-5) by matrix metalloproteinases and a disintegrin and metalloproteinase with thrombospondin motifs. A complex approach to accepting hypotheses for the projection of natality. Implications for designing targeted interventions are discussed. Experiments with SIV are proposed that may provide more direct supporting data for this possibility. Since that time, radiation therapy alone, systemic chemotherapy alone, or a combination of the two have been used extensively Because of the limited intraocular penetration of drugs administered systemically, the systemic and local toxicity of chemotherapy and radiation therapy and the high rate of recurrence, intravitreous chemotherapy, mainly using methotrexate, has become popular in the last decade, with encouraging results. Anesthetized hamsters were exposed to 1 MHz ultrasound at intensity levels currently being used clinically for therapeutic diathermy and hyperthermia (1-5 W/cm2, for 500 sec with constant beam scanning). Information support, illness perceptions, and distress in survivors of differentiated thyroid cancer.

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Geocoding and monitoring of US socioeconomic inequalities in mortality and cancer incidence: does the choice of area-based measure and geographic level matter?: the Public Health Disparities Geocoding Project. Some potentialities of living organisms under simulated Martian conditions. Oligoclonal IgM bands were performed in 22 patients with MS with a mean of 1.14 months of evolution. We conclude that OM-85 BV activates phagocytes through a CD14-independent pathway. Gas vesicle morphology was not affected by any mutation, implying that GvpM is required during initial stages of gas vesicle assembly. Serologic evidence indicates that the target for such a vaccine is antigenically conserved, and surface proteins expressed by placental parasites have been identified as vaccine candidates. This may lead to under-diagnosing and suboptimal pain treatment. The Tickle Talker has been shown to provide benefits in supplementing lipreading or aided residual hearing for hearing-impaired adults and children. Type I CRAds are based on mutation or deletion of early Ad genes.

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We combined parent and teacher ratings to determine DSM-IV ADHD status. Role for retinoblastoma protein family members in UV-enhanced expression from the human cytomegalovirus immediate early promoters. Grip strength was a strong and consistent correlate of work capacity. Selective CCK-A agonist activity has been reported to induce satiety in a variety of animals, including man, and thereby suggests a therapeutic role for CCK in the management of obesity. However, we currently are not benefitting from the full potential of its protective effects. Our risperdal medication dose findings demonstrate that combination of Lm-LLO-based vaccine with blocking of PD-1/PD-L1 interaction is a feasible approach with clinical translation potential that can lead to overall enhancement of the efficacy of anti-tumor immunotherapy. The aim of this study was to establish and validate a three-dimensional imaging protocol for the assessment of Computed Tomography (CT) scans of abdominal aortic aneurysms in UK EVAR trials patients. These findings suggest that a stable Cse4 nucleosome is maintained by dynamic chaperone-in-residence Scm3.DOI: http://dx.doi.org/10.7554/eLife.02203.001. Detection of metastatic cervical lymph nodes in recurrent papillary thyroid carcinoma: computed tomography versus positron emission tomography-computed tomography.

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Experiential cognitive therapy in the treatment of panic disorders with agoraphobia: a controlled study. Their interaural time difference sensitivity, however, is far too coarse to serve in sound localization. The molten phenol resin spontaneously formed a sphere and positioned itself in the center of the fluoropolymer ring pattern as a result of the difference of surface free energy and the equivalently zero-gravity condition in the oil bath. Interestingly, we failed to measure intracellular cAMP compartmentalization in actively chemotaxing cells. These swallows in NREM sleep were entirely comparable to swallows in wakefulness. To evaluate the in-vivo efficacy of solid SMEDDS containing combination of artemether and lumefantrine. Septoplasty for left ventricular outflow obstruction without aortic valve replacement: a new technique. In both male and female rats, ethanol intake promoted apoptosis in the liver. In rice (Oryza sativa), FLORAL ORGAN NUMBER2 (FON2), closely related to CLV3, is involved as a signaling molecule in a similar pathway to negatively regulate stem cell proliferation in the floral meristem (FM).

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