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Amsha (Amitriptyline)

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Amsha is used to treat depression. It is more popular than comparable drugs. Amsha is only available as a generic drug; all brands have been discontinued. Amsha is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Other names for this medication:
Amiclozor, Amicon, Amicure, Amidez, Amitin, Amitone, Amitrac, Amitrip, Amitryn, Amitryptyline, Amity, Amizep, Amline, Amoten, Amrea, Amsha, Amtipax, Anitryp, Aptric, Arpidox, Bluneel, Cotrip, Crypton, Eptanol, Goldep, Latilin, Librodep, Limbitrol, Nextrip, Normaline, Psycomer, Raitrip, Relidep, Ristryl, Sarotena, Sereval, Tablin, Tadamit, Teedep, Vanatrip, Zodep

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Also known as: Amitriptyline


Amsha target is the treatment of depression. Amsha is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Amsha is Amitriptyline. Amsha is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Amsha are Amsha, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amsha dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amsha are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Amsha if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Amsha if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Amsha is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Amsha is not approved for use by anyone younger than 12 years old.

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Pathological fibroproliferation after tissue injury is harmful and may lead to organ dysfunction. The mutant H chains were not secreted when expressed with either heterologous L chain. Muscle bundles were assumed to lie on lines that are simultaneously geodesics and lines of principal curvature of the diaphragm surface, and the class of surfaces that are formed by line elements that are both geodesics and lines of principal curvature was described. HCMV initiates infection and intracellular signalling by binding to its cognate cellular receptors and by activating several signalling pathways including those mediated by mitogen-activated protein kinase, phosphatidylinositol-3-OH kinase, interferons, and G proteins. Effect of bencyclane on blood circulation of the human calf muscle in the acute test using the 133-Xe tissue clearance method.

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In addition, cation-pi interactions are frequently observed to zip up the edges of the interface between intertwined chains or to involve hinge loop residues, thereby modulating stability. Peer-delivered hepatitis C testing and counselling: a means of improving the health of injecting drug users. The reduced expression of p73 correlated with overexpression of N-myc in a statistically significant manner. In addition, principal component analysis of 98 identified metabolites in S. These approaches might allow the rapid screen of chemicals for setting priorities for further studies to determine the dose-response relationship for chemical effects at low doses, to assess effects other than mutagenesis and/or tumorigenesis, or to establish qualitative and quantitative relationships of biomarkers to toxic effects. In contrast, no significant differences were observed in 125I-PYY binding over these same sampling intervals in either the medial preoptic area or the lateral hypothalamus.(ABSTRACT TRUNCATED AT 250 WORDS). To date, 20 different members of the TNF superfamily and 21 different receptors have been identified. Measurement of innate markers in nasal mucosa, tonsils and adenoids might lead to new views about the role of innate immunity in the upper airway.

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To study prospectively the health status, and especially the physical functioning, of polio survivors with and without postpoliomyelitis syndrome (PPS), and to identify prognostic determinants of change in physical functioning. In a multicenter trial, patients with symptomatic clinical stage I and stage II and III multiple myeloma were registered at diagnosis and those who responded to melphalan-prednisone (MP) were randomized either to receive interferon (2 mU/m2) subcutaneously three times per week or no maintenance. Pulmonary arterial hypertension (PAH) is a lethal disease and improved therapeutic strategies are needed. The derivatisation method includes acid activation and subsequent covalent coating of glass fibers with quaternary ammonium groups thereby giving the glass surface a high binding capacity for both proteins and peptides. A fused-ring acceptor unit in d-a copolymers benefits photovoltaic performance. Constructs based on all pedicle screws have a stronger hypokyphotic effect on the thoracic spine, with a predisposition to greater decompensation of the cervical spine. We found gamma 2 chain immunoreactivity in cancer cells in all cases of colon adenocarcinomas and squamous cell carcinomas but not in any of the sarcomas, supporting the view that the laminin-5 protein is specific for cells of epithelial origin. An early stage of visual information process related to N1 and a visual discrimination process related to N2 might be preserved in both MSA-C and MSA-P. Quercetin, a natural flavonoid, attenuates vacuolar formation in the optic tract in rat chronic cerebral hypoperfusion model.

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Our data demonstrate a predominant activation of CD8 T cells expressing activation markers and armed to mediate effector functions. Efficacy and safety of a seven-day, transdermal estradiol drug-delivery system: comparison with conjugated estrogens and placebo. The compounds obtained were identified as protocatechuic acid, gallic acid, catechol and p-hydroxybenzoic acid. Gatifloxacin and ethionamide as the foundation for therapy of tuberculosis. Using an Escherichia coli expression system and the PPDK cDNAs from F. These tests refer exclusively to the quality of functioning of the joints connecting transfixing pins and side bars. Load-controlled moderate and high-intensity resistance training programs provoke similar strength gains in young women. In fertilized eggs this association is prevented by one or more low molecular weight solutes. This allows the correlation of structural information contained in the fluorine chemical shift in one dimension with information on mobility from proton wideline spectra in the second dimension. Such alterations may be the driving force for the enrichment of CD44Bright DU145 cells after the mitochondrial DNA depletion, although the molecular mechanisms remain unclear.

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Preparation of anti-ciguatoxin monoclonal antibodies using synthetic haptens: sandwich ELISA detection of ciguatoxins. We assessed the validity of the OS-MRS in 2121 primary RYGB procedures performed at our center during a 25-year period. Despite these huge changes in receptor levels, dopamine transporter levels were not affected. Since intraocular lymphoma was first recognized almost 60 years ago, its treatment has gradually evolved. However, such information does become important in untargeted screening for unknown contaminants in environmental and food samples, which are generally based on a combination of high-resolution mass spectrometry and (multistage) tandem mass spectrometry. Compressive Behavior and Microstructural Characteristics of Iron Hollow Sphere Filled Aluminum Matrix Syntactic Foams. Mononuclear cells from smokers showed increased production of the pro-inflammatory cytokines IL-1beta, IL-6 and TNFalpha and enhanced proliferative response to mitogens as compared to non-smoking population. A total of 48 severe acquired brain injury rehabilitation institutes. Avian influenza has raised many apprehension in the recent years because of its potential transmitability to humans.

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Systemic inflammation as a driver of vascular calcification: a proof of concept. Isolated cecal infarction should be included in the differential diagnosis of acute pain in the right lower quadrant of the abdomen, especially in those patients on chronic hemodialysis. However, the tumor suppressor miRNAs are downregulated in breast cancer cells, since their major targets are oncogenic mRNAs. A special page is provided for contribution of new or additional information. Here we show that disrupting neuronal activity during ripple events impairs spatial learning. Thirty-six patients with idiopathic pulmonary fibrosis and 27 patients with hypersensitivity pneumonitis were studied. The available data include: activation of CAR, Cyp2b induction, hepatocellular hypertrophy and hyperplasia, absence of liver effects in KO mice, absence of proliferation in humanized mice, and exclusion of other possible mechanisms (e.g., genotoxicity, cytotoxicity, AhR, or PPAR activation), and indicate that the identified rodent liver tumor MoA for sulfoxaflor would not occur in humans. The modulatory effects of the anxiolytic etifoxine on GABA(A) receptors are mediated by the beta subunit.

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The bacterial plant pathogen Pseudomonas syringae causes disease in a wide range of plants. Water-pipe tobacco smoking is becoming increasingly more common among young people. Major depressive disorder, bipolar I disorder, intermittent explosive disorder, and cluster B personality disorders independently contributed to the presence of both anger and aggression. Patient age rather than time of surgery predicted operative approach and surgeon type. Mechanistic characterization of Toxoplasma gondii thymidylate synthase (TS-DHFR)-dihydrofolate reductase. Periorbital and Mediastinal Emphysema after Upper Gastrointestinal Endoscopy: Case Report of a Rare Complication.

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Vesicouterine fistula: a rare complication of vaginal birth after cesarean. The main reason for preferring the nebuhaler was the shorter administration time. However, other elements, such as the environment and the type of injury, could modify this response. Implementation of the american college of surgeons oncology group z1071 trial data in clinical practice: is there a way forward for sentinel lymph node dissection in clinically node-positive breast cancer patients treated with neoadjuvant chemotherapy?. In conclusion, our study demonstrated that HFCS treatment for 28 days could induce (1) changes in length of estrous cycle with extended estrous and diestrous stages, (2) altered ovarian and uterine histology, and (3) liver and renal lipid accumulation. Abruptly changing cows from one feeding system to another did not influence milk yield, milk composition, or body weight gain. The study involved a sample remeron reviews of 159 pupils attending eight classes in the fourth and fifth grades (age range 9-11 years). Transcutaneous monitoring showed a good correlation to ABG only during steady-state conditions. Unstimulated c-Abl knockout MEFs are less responsive to induction of NF-kappaB activity by trichostatin A, an HDAC inhibitor, suggesting that c-Abl might play a role in the HDAC-mediated repression of basal NF-kappaB activity.

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To determine the feasibility of correcting the uterine deformity in the diethylbestrol-exposed uterus and hypoplastic uterus. In this paper we have described five alphaA-crystallins in which charged and hydrophobic residues were inserted in the C-terminal extension. We identified 13 novel truncating mutations in ZFYVE26, 12 of which segregated at the homozygous or compound heterozygous states in 8 new SPG15 families while 1 was found at the heterozygous state in a single family. On the other hand, microorganisms release phytohormones, small molecules or volatile compounds, which may act directly or indirectly to activate plant immunity or regulate plant growth and morphogenesis. Alcohol consumption, cigarette smoking and risk of subtypes of oesophageal and gastric cancer: a prospective cohort study. The release of triprolidine from the EVA matrix follows a diffusion controlled model, where the quantity released per unit area is proportional to the square root of time. We have used the guinea pig model of tuberculous pleurisy to examine several aspects of the immune response to this antigen-specific inflammatory event.

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Genetic analyses of live-animal ultrasound and abattoir carcass traits in Australian Angus and Hereford cattle. Larvicidal potential of five Philippine plants against Aedes aegypti (Linnaeus) and Culex quinquefasciatus (Say). Despite increasing interest in local microvascular alterations associated with inflammatory bowel disease (IBD), the potential contribution of a primary systemic vascular defect in the etiology of IBD is unknown. Patients undergoing TORS for known tonsillar cancer were retrospectively reviewed. C4d deposition in the glomeruli and peritubular capillaries associated with transplant glomerulopathy.

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Rodent work suggests a role of the appetitive peptide leptin in cocaine periactin pediatric dose -seeking behaviours. Optimization of osmotic dehydration in different plant cells has been investigated through the variation of parameters such as the nature of the sugar used, the concentration of osmotic solutions and the processing time. We report our experience with RTX in the treatment of children with LN. Chronic vagus nerve stimulation (VNS) continues to be evaluated as an adjunctive treatment for medically intractable seizures. Treatment with hydroxocobalamin may ameliorate the clinical features of early-onset disease and prevent clinical late-onset disease. Insulin-like growth factor-binding proteins in healthy and atretic follicles during natural menstrual cycles. Biological and biosimilar therapies in inflammatory conditions: challenges for the Central and Eastern European countries.

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Smooth-pursuit eye-tracking data of 63 schizophrenic patients and 52 normal controls are presented and compared with data collected on the same subjects 2 years earlier. Wherever possible articles cited were obtained from the journals and where this was not possible abstracts were obtained. Small cell type neuroendocrine carcinoma colliding with squamous cell carcinoma at esophagus. A partial deficiency was demonstrated in sera from some patients with dysostosis multiplex without mucopolysacchariduria. Dynamic contrast-enhanced magnetic resonance imaging: fundamentals and application to the evaluation of the peripheral perfusion. Anticipatory smooth eye movements, an overt indicator of expectations and predictions, may not be operating in isolation, but may be part of a global process in which the brain analyzes available cues, formulates predictions, and uses them to control perceptual, motor, and cognitive processes. At least one third of NB cases present without distant metastasis and cytotoxic therapy does not alter the natural history.

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