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Antidep (Imipramine)

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Antidep is a tricyclic antidepressant used to treat symptoms of depression. Antidep is sometimes used to treat bed-wetting in children ages 6 and older. Antidep may also be used for purposes not listed in this medication guide.

Other names for this medication:
Alzoset, Anxidep, Anxitab, Anxofit, Depik, Depnil, Depof, Depranil, Deprid, Depsin, Depsol, Depsolam, Diamin, Diazariv, Elamin, Eldep, Elidep, Endopax, Estidep, Finezol, Imidiaz, Imikon, Imilor, Iminza, Imipam, Imipra, Imipramine, Imodep, Impramine, Impranit, Imprim, Imprin, Karthin, Libomin, Microdep, Nimipose, Normadep, Talendep, Toframine, Trydep

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Also known as: Imipramine


Antidep is a tricyclic antidepressant used to treat symptoms of depression. This medicine is sometimes used to treat bed-wetting in children ages 6 and older.


This section provides information on the proper use of a number of products that contain imipramine. It may not be specific to Antidep-PM. Please read with care.

Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (capsules): For depression: Adults—At first, 75 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day, unless you are in the hospital. Some hospitalized patients may need higher doses. Teenagers and older adults—At first, 25 to 50 mg per day using the tablets. Your doctor may adjust your dose as needed and switch you to the capsule form. However, the dose is usually not more than 100 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): For depression: Adults—At first, 75 milligrams (mg) per day. Your doctor may adjust your dose as needed. However the dose is usually not more than 200 mg per day. Some hospitalized patients may need higher doses. Teenagers and older adults—30 to 40 mg per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 100 mg per day. Children—Use and dose must be determined by your doctor. For enuresis (bedwetting): Children 6 years of age and older—At first, 25 milligrams (mg) once a day, taken 1 hour before bedtime. Your doctor may adjust the dose as needed. Children younger than 6 years of age—Use and dose must be determined by your doctor.


If you overdose Generic Antidep and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Antidep overdosage: agitation, bluish skin, convulsions, difficulty breathing, dilated pupils, drowsiness, heart failure, high fever, involuntary writhing or jerky movements, irregular or rapid heartbeat, lack of coordination, low blood pressure, overactive reflexes, restlessness, rigid muscles, shock, stupor, sweating, vomiting.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Antidep are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Antidep if you are allergic to it, or if:

you recently had a heart attack; or you are allergic to other antidepressants (amitriptyline, amoxapine, clomipramine, desipramine, doxepin, nortriptyline, protriptyline, or trAntidep).

Do not use Antidep if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

Tell your doctor if you have ever had:

heart disease, stroke, or seizures; bipolar disorder (manic-depression), schizophrenia or other mental illness; kidney or liver disease; overactive thyroid; narrow-angle glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

It is not known whether Antidep will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using Antidep.

Do not give this medicine to a child without medical advice. Antidep is not approved to treat depression in anyone younger than 18 years old. This medicine should not be used to treat bed-wetting in a child younger than 6 years old.

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This report concerns a case of locked twins encountered at the Mayo Clinic. Characterisation of left ventricular myocardial fibrosis in adult congenital heart disease by contrast and deformation echocardiography validated by CMR. We investigated whether HMGB1 and HSP70 released from necrotic monocytes/macrophages, can act as danger signals to mediate proinflammatory cytokine responses to bacterial endotoxin or lipopolysaccharide (LPS). In this work, we discuss conceptual requirements for model version control. For each piglet, 41 behaviors were scored, timed, summed and clustered into 9 behavioral categories. Oral absorption of peptides through the cobalamin (vitamin B12) pathway in the rat intestine. These results indicate that time perception and motor timing rely on similar cerebral structures. Cause-specific infant mortality rate in Qatif area, eastern province, Saudi Arabia. Recombinant modified vaccinia virus ankara expressing the surface gp120 of simian immunodeficiency virus (SIV) primes for a rapid neutralizing antibody response to SIV infection in macaques. Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy.

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Comprehensive I-125 multi-seed comparison for prostate brachytherapy: dosimetry and visibility analysis. Fold-preserving electronic cleansing using a reconstruction model integrating material fractions and structural responses. The effectiveness of family interventions may be improved by concentrating on elements of objective burden that best predict subjective burden. Generation of hydrogen peroxide (H2O2) in RBC was observed upon ozone exposure but was significantly suppressed by CO treatment before ozone exposure. Spontaneous lesions are usually controlled with office debridement. Properties of and proteins associated with the extracellular ATPase of chicken gizzard smooth muscle.

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Erythromycin-resistant Staphylococcus spp isolated from milk samples of lactating cows may serve as reservoirs of erm genes homologous to those described in human isolates. Does vitrification of human ITT have potential benefits in an in vivo murine xenotransplantation model?. A comparison of lansoprazole and ranitidine in the treatment of erosive oesophagitis. Aluminum phthalocyanine tetrasulfonate (AIPcS4) was found to inactivate VSV at a rate one-fourth that of the silicon phthalocyanines (Pc 4 and Pc 5). An additional regulatory loop is provided by the reactivation of the short form of STAT5 through glucocorticoid receptor association.

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The Epidermal Growth Factor (EGF) is a biologically active salivary protein that aids in the rapid regeneration of the oropharyngeal and upper digestive tract mucosas. Although it is speculated that LPA might play a role in pathophysiologic processes in vivo, not only its role but also even a possible alteration in its blood concentration under specific diseases is essentially unknown. All mice were sacrificed 4 weeks after the last bacterium inoculation of Groups P and DP. An X-ray crystal structure reveals that they bind in a region near the p-loop and the hinge region of MK2a. Optic disc area measurement is smaller in ONHD compared to healthy subjects with fundus photography, unlike time-domain and spectral-domain optical coherence tomography in which the reverse is true. The effects of ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, on morphine-induced place preference were examined in mice. Promoting professional competence, providing quality care, and improving health care processes are issues of major importance in Air Force Optometry as well as the entire Air Force Medical Service.

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Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents. In this work, we developed a facile fabrication method for a novel nanofibrous self-assembled peptide amphiphile (PA) and poly(ethylene glycol) (PEG) composite hydrogel system with independently tunable biochemical, mechanical, and physical cues without any chemical modification of polymer backbone or additional polymer processing techniques to create synthetic ECM analogues. Most importantly, this work illustrates the potential applicability of the technique to the entire human chromosome complement. The selenium status in the food grains of the agricultural lands of northern parts of India was estimated by using the HG-AAS technique. Our study provides new insights into the mechanisms of acquired resistance of Bcl-2 and MDM2 inhibitors in acute leukemia models and suggests that certain sequential or combination treatment of these two distinct classes of apoptosis-inducing agents should be tested as new treatment strategies for acute leukemia in the clinic. USE OF SEMI-AUTOMATIC INHALATION ANESTHESIA IN EXPERIMENTS ON ANIMALS. Blood cobalt concentrations in maintenance hemodialysis patients who had been treated 13-20 months previously with cobaltous chloride were significantly higher than those in maintenance hemodialysis patients who had not received cobalt. Once cell migration is initiated, distinct cell fates are determined within each migrating branch. The ultrastructural reorganization of F-actin after arsenic trioxide (ATO) treatment was estimated using a combination of pre- and post-embedding techniques with biotinylated phalloidin and QD-streptavidin conjugates or colloidal gold (AU) conjugated is klonopin safe to take while breastfeeding to streptavidin.

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Immobilization devices have only been studied recently in a scientific manner in the domain of chest tumors, presumably because other factors such as tumor motion were felt to be more important causes of treatment uncertainties. Mass cultivation of human retinal pigment epithelial cells with microcarrier. All consecutive renal transplant patients of all ages and both genders on regular follow up, presenting with GI complaints and in whom GI endoscopic biopsies were performed, were included. Occupancy principle: identity with that of mean transit time of tracers in biological systems. The test conditions (flow rate, concentration, humidity) were those relevant to the application, and the effect of variation of these conditions was also studied. Mosaic trisomy 21 was found in a blood karyotype of the first child, a second pregnancy ended in spontaneous abortion, and a full trisomy 21 was found at prenatal diagnosis of the third pregnancy of this same couple.

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We have observed a high incidence of ulnar neuropathy in musicians with dystonic flexion of the ipsilateral little and ring fingers. Histological determinants for different types of local recurrence after breast-conserving therapy of invasive breast moduretic drug side effects cancer. Atypical presentation of fat embolism syndrome after gunshot wound to the foot. Air physiogram: technique for visualization of the resected physis in percutaneous epiphysiodesis. A ligand blot overlay assay was used to search for novel dystroglycan binding partners in postsynaptic membranes from Torpedo electric organ. Further, CypA plays critical roles in the replication of several viruses. The authors studied prospectively 373 consecutive chest x-rays of children, ranging in age from 0 to 17 years, who were examined for suspected pneumonia.

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