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Apsolam (Alprazolam)

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Apsolam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Apsolam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Apsolam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aderta, Alcalm, Aldip, Allam, Alprawin, Alprocontin, Alzac, Alzonex, Alzorix, Ansilumirm, Anxiflu, Anxigo, Azoslip, Benzolam, Copax, Depoxit, Eurolam, Faxtin, Finezol, Nitril, Onapract, Optizole, Serxanti, Setlan, Unixl, Zepro, Zolam, Zolax, Zolent, Zolorel, Zopain, Zopax

Similar Products:
Silagra, Micardis, Coreg, Addyi, Zantac, Onida, Venjoy, Methopar, Oxytetracycline, Hyglim, Tenochek, Jufurix, Axynol, Alltop,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take Apsolam exactly as prescribed by your doctor. Follow all directions on your prescription label. Never use Apsolam in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.

Apsolam may be habit-forming. Never share Apsolam with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Do not crush, chew, or break a Apsolam extended-release tablet. Swallow the tablet whole. Call your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms. Do not stop using Apsolam suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Apsolam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Apsolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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(2) The organic groups of the formed films became decomposed in a few minutes with UV irradiation coupled with a water solution of ammonium persulfate (APS). Adolescent subthreshold-depression and anxiety: psychopathology, functional impairment and increased suicide risk. In attempts to elucidate factors stimulating bone resorption in patients with different inflammatory diseases in the vicinity of the skeleton, e.g., peridontal disease and rheumatoid arthritis, we are investigating the presence of bone-resorbing activity in a variety of inflammatory exudates. We have developed a procedure for purifying assembly-competent tubulin from Aspergillus nidulans. Hormonal influences on the glucide metabolism of striated muscle. Since the management of nasopharyngeal cancer is primarily irradiation, a well-planned aggressive treatment program using supravoltage therapy is recommended. EXPERIENCE IN THE ORGANIZATION OF OBSTETRIC AND GYNECOLOGIC SERVICE TO THE POPULATION OF THE KALININGRAD TERRITORY. In this prospective study, 18 treatment-refractory patients with DSM-IV schizophrenia (10 nonsmokers and 8 smokers) were treated with clozapine at a target dose of 100 mg h.s. We have developed an inducible blood cell line from Drosophila for studying the immune response in vitro. However, the bone marrow stromal cell line and muscle derived cells showed more responsiveness to recombinant human bone morphogenetic protein-2 than did the other cell types.

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The procedure was successfully performed in a consenting woman with an abdominal mass. This paper reviews the clinical presentation, the molecular genetic diagnosis and therapeutic approaches of this syndrome including the controversies concerning prophylactic colectomy for cancer or gene carriers. The changes in body weight and height were similar between the groups at the end of the study. Athletic appearance drew attention, because the patient denied practicing sport. The prognosis of retained primary molars without successors: infraocclusion, root resorption and restorations in 111 patients.

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Anticipated enacted stigma from any source, PTS, and greater perceived likelihood of deploying again were unrelated to help-seeking intentions from a mental health professional and MD/APRN. To assess the effect of reverberation on the neural coding of amplitude envelope, we recorded from single units in the inferior colliculus (IC) of unanesthetized rabbit using sinusoidally amplitude modulated (AM) broadband noise stimuli presented in simulated anechoic and reverberant environments. A control study of a school-based life skills education on prevention of behavior problems in third-grade schoolchildren. Angiotensin II AT1-receptor blockers (AT1-s) prolong survival in experimental postischemic (coronary artery ligation) heart failure (CHF) in rats. Nasal-type T/NK lymphomas: a clinicopathologic study of 13 cases. A case of transitional cell papilloma of the ureter is reported in a seven-year-old boy who had a history of left flank pain, involuntary voiding and nocturnal enuresis, and was found to have ureterohydronephrosis of a solitary left kidney and renal insufficiency. The Minolta transcutaneous jaundice device could be used as a screening instrument, leading to the avoidance of invasive blood samplings for preterm and VLBW infants.

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Neighborhood perceived/built environment and physical activity (PA) associations have been examined for adolescents around homes, but not surrounding schools. Preliminary results using cosmid or YAC probes that hybridize to regions rich in GC sequences also revealed double fluorescent spots on a single chromatid. Maternal rubella-specific antibody prevalence in Ethiopian infants. After intervention using TRCI approach, the presence of a weaker RAP is an indicator of imminent RAO. As a result, the luciferase activity of T7T7/T7Luc-transfected DCs was more than four times greater than that of DCs transfected with pCMVLuc, a commonly used nonviral vector. TOMOGRAPHY OF THE JOINT IN THE DIAGNOSIS OF RHEUMATOID ARTHRITIS. Age, period, and cohort effects on generalized trust in Reform-Era China, 1990-2007. Such a cross-link of poly(MPC) slightly increases the friction of CLPE by gamma-ray irradiation but provides a stable wear resistant layer on the friction surface.

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Survival rates were monitored, clinical and pathological scores of aGVHD were determined after bone marrow transplantation (BMT), and the serum cytokine levels were examined on the 7th day after BMT. Mycobacterial granulomas of the skin and subcutis can be caused by one of a number of pathogens. Philadelphia-negative secondary acute myeloid leukaemia during imatinib treatment for chronic phase chronic myeloid leukaemia. Effective sharing of information is done through the medium of shared records, shift handovers, ward rounds, and informal verbal exchanges. Little is known about the prevalence of target organ damage in previously undiagnosed hypertension. Upon stimulation with the activating anti-integrin beta 1 antibody, both transfectants became more adherent to the substratum regardless of the type of laminins coated, although their preference for laminin isoforms remained unaltered. These results show that genetic analysis can be performed on all fetal NRBCs, including female fetal cells that cannot be distinguished from maternal cells based on FISH analysis alone. Influence of centrifugation and different extenders on post-thaw sperm quality of ram semen.

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Sixty-five cases of status epilepticus in 51 children were analysed. They were less willing to use therapeutic strategies to help the older patient, and they were not optimistic that psychiatrists or psychologists could help the suicidal patient. In the present study we have evaluated the effect of acute haemorrhage in the rat on the acid-base status, the red cell affinity for oxygen in vivo, and Ep production. Purified STI had strong inhibitory effect on human umbilical vein endothelial cells migration and tubulogenesis in fibrin matrix, without toxic effects in the studied doses. However, the mean lesion size, although decreased, did not differ significantly from that in the placebo group. Ovulation rate and subsequent lamb production in the nulliparous and primiparous ewe.

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Increasing trauma intensity (100-500 rev) resulted in a progressive failure in hepatic Kupffer cell phagocytosis and a progressive increase in plasma lysosomal enzyme levels when tested at 60-min post-trauma. Chimney stoves modestly improved indoor air quality measurements compared with traditional open fire stoves: results from a small-scale intervention study in rural Peru. The clinical isolate grew faster in Peptone-yeast extract-glucose (PYG) medium, transformed more rapidly from a trophozoite to cyst and exhibited increased cytopathic effect on cultured cells. Thus indicating the direction of current flow the height of the cone represents the current intensity. Unwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase. An unusual cause of a marked leukocytosis and an abnormal blood film. The cyclopean illusion is the apparent lateral shift of stationary stimuli on a visual axis that occurs when vergence changes. The optical confinement is attributed to the disorder-induced scattering and interference. Bromodeoxyuridine immunohistochemistry of epon-embedded undecalcified bone in a canine fracture healing model. Consecutive patients with STEMI who were not enrolled in the trial were entered into the registry.

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Divergent responses of Pygoscelis penguins reveal a common environmental driver. Effect of in vivo ischemia on dog heart slice function in vitro. Comparison of their prescription feedback with their own quality criteria gave each doctor the proportion of acceptable and unacceptable treatments. Leukapheresis of neutrophil granulocytes in mice increased the myelopoietic activity of their serum. Immigrants is an important minority in many countries, but little is known how they are self-selected. Using the alkaline filter elution technique, pieces of tissues from six organs: lung, intestine, liver, brain, muscle, and heart have been examined for DNA damage, mainly DNA single strand breaks. Aging lengthens circadian period for wheel-running activity in C57BL mice. Three kinetic sub-models, corresponding to each reactor, were developed and then combined in a comprehensive ASM1-based model. To describe preventive health examinations/tests and behaviors of persons with traumatic spinal cord injury (SCI).

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The results suggested that the walking velocity selected by individuals with COPD serves to minimize energy cost per distance. This study was performed to clarify whether different slopes of the ramp exercise test influence exercise tolerance, exercise limiting factors, and respiratory pattern in patients with chronic obstructive pulmonary disease (COPD). It was concluded that young patients with stage I disease can be safely treated by subtotal thyroidectomy. The proposed method should prove useful especially for accelerated high-resolution (1) H MRSI of the brain. We further correlate the changes in partitioning with the actual rates of RCL insertion for several of the variants upon reaction with the different proteinases as determined by fluorescence spectroscopy of specific RCL-labeled inhibitor mutants.

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To assess the predictors of intentions to quit smoking in a community sample of Aboriginal smokers of reproductive age, in whom smoking prevalence is slow to decline. Inactivation of prrB results in a substantial reduction of photosynthetic spectral complexes as well as in the inability of cells to grow photosynthetically at low to medium light intensities. By using a cross-sectional study design, we obtained data on fast food consumption and nutrient intake (from four separate 24-hour dietary recalls) and nutritional parameters (from chart abstraction) for 194 randomly selected patients from 44 hemodialysis facilities in northeast Ohio. More and more people consume these infusions as daily beverages as well as for health purposes. Proportion positive for Epstein-Barr virus, cytomegalovirus, human herpesvirus 6, Toxoplasma, and human immunodeficiency virus types 1 and 2 in heterophile-negative patients with an absolute lymphocytosis or an instrument-generated atypical lymphocyte flag. This lower performance was apparent also when values were corrected for total body mass (MP) and FFM (MP and PP), but not when corrected for cross-sectional area of thigh and calf.

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This model offers unique opportunities for study of this poorly understood gastrointestinal parasite. Patient-specific optimization was examined in five healthy volunteers and two multiple sclerosis patients. This has important implications in understanding differences in mechanisms controlling MT expression in the kidneys and liver. Very low interface charge density leads to hysteresis-free devices. Bursae were imprinted onto nylon membrane and then hybridized with a cloned digoxigenin (DIG)-labeled cDNA probe.

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Intraoperative radiotherapy and cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. The time course was does zyrtec come in 5mg pills biphasic with an early peak at 10 min and a later peak at 20 min. Seroprevalence and Risk Factors for Hepatitis C Virus Infection among General Population in Central Region of Yemen. RNA levels varied in different body parts of the adult mosquito. The molecular events associated with bile-salt interactions with the plasma membrane affecting ion fluxes may relate to their unique effects on sterol absorption. The effective charge of a rigid polyelectrolyte (PE) approaching an oppositely charged surface is studied. Two copper concentrations were tested (80microgL(-1) and 160microgL(-1) final concentrations), set, respectively, below and above the ligand binding capacity of the water samples. Stabilizer reaction-free 99mTc-sulfur suspension for liver, spleen, and bone-marrow scanning. Previous works have characterized almost exclusively purified carbohydrates or their derivatives, having neglected the large amount of gums and carbohydrates already used in the paper, food, or textile industries.

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Anorexia nervosa is a complex psychiatric illness that can lead to severe physical complications. On the other hand, these sarcoma cell lines do not express marked amounts of other ligands (such as CDII/18 or sialyl-Lex) for other endothelial adhesion molecules (ICAM-I, ICAM-2, E- and P-selectin) indicating that the VLA-4-VCAM-I dependent pathway might be of major importance in sarcoma extravasation. Though it is highly metastatic, metastasis to the gastrointestinal tract is rarely reported. Hydrogen-bond-mediated complexation of a CG what is the recommended dose of zofran base pair by a hexylureido phthalimide and a hexylureido isoindolin-1-one was studied by (1)H NMR spectroscopy in an organic solvent. Notch 1-4 were checked by real-time quantitative polymerase chain reaction and flow cytometry from different levels.

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We searched for a viral aetiology for non-small cell lung cancer (NSCLC), focusing on Merkel cell polyomavirus (MCPyV). The Korean version of the Childhood Autism Rating Scale (K-CARS) was used to assess clinical severities. On the other hand, type II IFN has been considered as pathogenic in multiple autoimmune diseases leading to the paradigm of TH-1 type autoimmune diseases. Thus, we evaluated the impact of antigenic diversity of repetitive and family dimorphic domains of the merozoite surface protein 2 (MSP-2) on immune response of 96 individuals living in Peixoto de Azevedo (MT-Brazil), by ELISA using recombinant MSP-2 proteins. Conservative treatment with oral itraconazole alone is effective in cases with incomplete obstruction. COLORIMETRIC DETERMINATION OF FREE FATTY ACIDS IN BIOLOGICAL FLUIDS. Viral and grazer regulation of prokaryotic growth efficiency in temperate freshwater pelagic environments. Several recombinant clones expressing full or part of 29.5 K polypeptide, and none expressing 31 K polypeptide were revealed.

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Significant vascular growth, and a hypotensive response and regression of vascular growth after treatment with an ET antagonist demonstrate the endothelin-dependency present in some hypertensive models. Gait event detection for FES using accelerometers and supervised machine learning. Total analysis system for tumor promoter microcystins produced by cyanobacteria. The platforms were loaded with the hydrophobic drug ibuprofen by swelling in its ethanol solution. Here, we test for inefficient purifying selection acting on the cytochrome oxidase I (cox1) mitochondrial gene in 3 clades of bdelloids. Diagnostic studies included CT scan, ERCP, arteriogram, and percutaneous needle aspiration cytology. The available information about the occurrence of disease in free-ranging wildlife is mainly derived from surveys based on serological evidence. Prospective study in subjects of European descent with supratentorial ICH who underwent genome-wide genotyping. Binding of PNAs to RNA resulted in site-specific termination of both reverse transcription and in vitro translation, precisely at the position of the PNA.RNA heteroduplex. Despite prominent neurological symptoms reported in Takayasu arteritis (TA), a complete evaluation of the cerebral circulation has not been consistently performed.

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It was thus our desire to try to simplify the sample collection and data acquistion and reduction processes as much as possible, in the effort to make the procedure more adaptable for incorporation into routine monitoring programs. Medical certification standards in the evaluation of inability to work. Distal airways are protected from goblet cell metaplasia by diminished expression of IL-13 signalling components. Special care is finally given to the influence of the kinetic of the interactions for the proton NMR of bound molecules in SUV, which can constitute a good model for the study of dynamical processes at the membrane surface. One potentially significant, yet under-researched, issue is the social stigma surrounding diabetes. Implicit learning of mappings between forms and metaphorical meanings. Lactoferrin absorbed into the blood was also detected in the bile and reached a peak value 12 h after oral administration. Quartz concentrations decreased over time, with measurements collected in the 1970s significantly greater than those collected later. Phylogenetic trees based on the nucleotide sequences of the HN and F genes revealed that recent Taiwanese isolates had evolved into two groups. Although the correlation of DNA damage with aging differed in what classification of drug is trazodone the different six organs, damage was significantly higher in SAMP1 mice than SAMR1 mice at later life in all organs.

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Expression levels of ZO-1, occludin, claudins, E-cadherin, human Scribble protein and Snail were determined in HeLa and CaSki cervical carcinoma cell lines by imuunohistochemistry (IHC) and Western blotting. The compensatory intervention consisted of four 45-minute sessions of instruction in the use of three internal compensatory strategies, including verbalization, chunking, and pacing. FLAME PHOTOMETRY IN THE DETERMINATION OF SODIUM, POTASSIUM AND CALCIUM IN TISSUES. Here we report that GABA injection into intact Clione resulted in a change of the stabilized orientation and swimming with a tilt of approximately 45 degrees to the left. Late results of radical denervation of the carotid sinus in the treatment of bronchial asthma. The higher dose of orexin-B, on the other hand, exerted effect on insulin secretion only at min 60 of experiment and neither doses changed blood glucose level. Prostate cancer after subcapsular prostatectomy diagnosed as benign prostate hypertrophy--clinico-pathological analysis.

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It is a major risk factor for suicide as well as coronary artery disease (CAD) and sudden cardiac death (SCD). These genes and their derived enzymes can facilitate the production of cheese and cheese derivatives with potential for tenormin brand name use as ingredients in consumer foods. We have previously shown that toxin-coregulated pilus (TCP), a type IV pilus that is an essential Vibrio cholerae intestinal colonization factor, serves as a receptor for CTXphi. These data may be partially explained by PKC-independent phosphorylation of MARCKS in response to thrombin stimulation. Minimal symptoms of brain tumor: a case report of clinical judgment.

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The latter finding indicates that a direct regulatory link exists between the establishment of the competent state and the synthesis of AddAB, required for recombination of internalized donor DNA. Standards for determining repair requirements for technical medical equipment. The aim of the present study was to investigate mstn expression in a large mammal (the pig) in order to ascertain whether distinct expression changes of this factor might be linked to the fiber-type composition of the muscle examined and/or to specific developmental stages. Multidimensional evaluation of soil pollution from railway tracks. Although this chlorine HAZMAT incident did not cause severe injuries, and only a limited number of persons required admission to the hospital, some valuable lessons were learned.

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When DBP preparations containing 27-hydroxycholesterol and various phosphatidylcholines were used for the LCAT reaction, both monoesters and diesters were produced. We sought to determine the clinical course of patients with ventriculoperitoneal (VP) shunts who undergo appendectomy for appendicitis. Body weight, fasting blood glucose level, and blood pressure of study participants were also determined at each time period. A complex process of maturation called capacitation is an essential step for spermatozoa to fertilize oocytes. A fragment of the lesion was biopsied and histologic findings were compatible with a diagnosis of proliferative nodule in a giant congenital nevus. Contrast-enhanced dynamic MR imaging with gadobenate dimeglumine significantly increases sensitivity and accuracy over unenhanced imaging for the characterization of focal hepatic lesions, and delayed MR imaging contributes to the improved detection of lesions.

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