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Aviglen (Glibenclamide)
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Aviglen

Aviglen is an effective and affordable medication for lowering blood sugar, but it can sometimes make your blood sugar too low especially if you have kidney problems. Aviglen tells your pancreas to increase the amount of insulin it produces in your body. Insulin works to lower your blood sugar.

Other names for this medication:
Afdiex, Benclamet, Benformin, Bionil, Codica, Combidos, Comdiab, Daocon, Diabetnil, Diabetrol, Diolin, Duotrol, Dutrol, Euglucon, Eumet, Glibact, Glibenclamide, Glibet, Glibson, Glimsug, Glinil, Glitrac, Glucomin, Gluconil, Glucosafe, Glucotrac, Glunil, Glybenclamide, Glybid, Glyboral, Glybovine, Glycurub, Glymep, Iscept, Melitus, Monomet, Pionorm, Secrin, Sugatrol, Sugnl, Sycored, Symet, Triglucored, Triglycomet

Similar Products:
Catapres, Diovan, Maxalt, Levothroid, Sildigra, Celebrex, Biorinol, Progesterone, Koptin, Capocid, Fexodis,

Also known as: Glibenclamide

Description

Aviglen and metformin is a combination of two oral diabetes medicines that help control blood sugar levels.

Aviglen and metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes. Aviglen and metformin is not for treating type 1 diabetes.

Dosage

Usual Adult Dose for Diabetes Type 2:

Doses provided as Aviglen-metformin -As Initial Therapy in Patients with Inadequate Glycemic Control on Diet and Exercise Alone: Starting dose: 1.25 mg-250 mg orally once a day -Consider a starting dose of 1.25 mg-250 mg orally twice a day for patients with fasting blood glucose (FBG) greater than 200 mg/dL or HbA1c greater than 9% Maintenance Dose: Increase in increments of 1.25 mg-250 mg per day every 2 weeks up to the minimum effective dose to achieve glycemic control Maximum Initial Dose: 10 mg-2000 mg per day -Patients with Inadequate Glycemic Control on a Aviglen (or another Sulfonylurea) and/or Metformin: Initial dose: 2.5 mg-500 mg or 5 mg-500 mg orally twice a day Maintenance Dose: Increase in increments of no more than 5 mg-500 mg to the minimum effective dose to achieve adequate blood glucose control Maximum Dose: 20 mg-2000 mg per day Comments: -Give with meals; 5 mg-500 mg dose should not be used as initial therapy due to an increased risk of hypoglycemia; initial doses should be conservative to avoid hypoglycemia largely due to Aviglen and gastrointestinal side effects largely due to metformin. -For patients who are switching to combination therapy, initial doses should not exceed the daily dose of Aviglen (or equivalent sulfonylurea) and metformin already being taken; the decision to switch to the nearest equivalent dose should be based on clinical judgement. -Addition of thiazolidinedione may be appropriate for patients not adequately controlled on Aviglen-metformin; in patients experiencing hypoglycemia, consider reducing the dose of the Aviglen component. -Monitor patients closely for signs and symptoms of hypoglycemia. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Detailed Aviglen/metformin dosage information

Overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include hypoglycemia symptoms as well as the following:

  • seizures
  • loss of consciousness

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Aviglen dosage information

Side effects

The most common side effects associated with Aviglen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

It is very important to follow carefully any instructions from your health care team about:

  • Alcohol—Drinking alcohol may cause severe low blood sugar. Discuss this with your health care team.
  • Counseling—Other family members need to learn how to prevent side effects or help with side effects if they occur. Also, patients with diabetes may need special counseling about diabetes medicine dosing changes that might occur because of lifestyle changes, such as changes in exercise and diet. Furthermore, counseling on contraception and pregnancy may be needed because of the problems that can occur in patients with diabetes during pregnancy.
  • Travel—Keep your recent prescription and your medical history with you. Be prepared for an emergency as you would normally. Make allowances for changing time zones and keep your meal times as close as possible to your usual meal times.
  • In case of emergency—There may be a time when you need emergency help for a problem caused by your diabetes. You need to be prepared for these emergencies. It is a good idea to wear a medical identification (ID) bracelet or neck chain at all times. Also, carry an ID card in your wallet or purse that says you have diabetes and a list of all of your medicines.
Check with your doctor right away if you start having chest pain or discomfort, nausea, pain or discomfort in the arms, jaw, back, or neck, shortness of breath, sweating, or vomiting while you are using this medicine. These may be symptoms of a serious heart problem, including a heart attack.

Too much Aviglen can cause low blood sugar (hypoglycemia) when it is used under certain conditions. Symptoms of low blood sugar must be treated before they lead to unconsciousness (passing out). Different people may feel different symptoms of low blood sugar. It is important that you learn which symptoms of low blood sugar you usually have so that you can treat it quickly and call someone on your health care team right away when you need advice.

Symptoms of hypoglycemia (low blood sugar) include anxiety, behavior change similar to being drunk, blurred vision, cold sweats, confusion, cool, pale skin, difficulty in thinking, drowsiness, excessive hunger, fast heartbeat, headache (continuing), nausea, nervousness, nightmares, restless sleep, shakiness, slurred speech, or unusual tiredness or weakness.

If symptoms of low blood sugar occur, eat glucose tablets or gel, corn syrup, honey, or sugar cubes; or drink fruit juice, non-diet soft drink, or sugar dissolved in water. Also, check your blood for low blood sugar. Glucagon is used in emergency situations when severe symptoms such as seizures (convulsions) or unconsciousness occur. Have a glucagon kit available, along with a syringe or needle, and know how to use it. Members of your household also should know how to use it.

Do not take this medicine if you are also using bosentan (Tracleer). Also, make sure your doctor knows about all other medicines you are using for diabetes, including insulin.

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Despite high levels of resilience, doctors had high levels of burnout and secondary traumatic stress. Both the adults and the chicks replied to controls (two voices) but not to modified signals (one voice being experimentally suppressed). The integration of catalyst and building block provides assembling component as well as its energy of motion. Increased occurrence of preterm delivery and low birth weight suggest that close monitoring is warranted. This article provides an overview of the current literature on the impact of microbial skin sealant to prevent SSIs. pylori is also one of the most genetically diverse of organisms, and variations are not only found in outer membrane adhesins, but also in two major virulence factors, the VacA cytotoxin and the cag pathogenicity island. Purification, crystallization and X-ray analysis of Hibiscus chlorotic ringspot virus. For each country, trends in caries experience (measured by DMFT index-the number of decayed, missing, and filled permanent teeth) were analyzed in an age, period, and cohort (APC) analysis using partial least square regression. Furthermore, 30-39-year-old workers and 40-49-year-old workers were significantly associated with adequate consumption of water compared to young workers.

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Congenital murine osteopetrosis inherited with osteosclerotic (oc) gene: hematological characterization. Mouse lung adenocarcinoma (LA-795)--study by histochemistry, light and electron microscopy. SOD activity was increased significantly in the antigen-sensitized group. On one end of the continuum we observed the classically, described staircase movements with individual movements separated in time. Caged RNA is reduced in translational activity, whereas illumination of caged RNA with ultraviolet light leads to recovery of translational activity. Latent class analysis of antisocial behavior found four classes.

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