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Benclamet (Glibenclamide)

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Benclamet is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes. Benclamet is in a class of medications called sulfonylureas.

Other names for this medication:
Afdiex, Aviglen, Benclamet, Benformin, Betanase, Bionil, Codica, Combidos, Daocon, Daonil, Diabetnil, Diabetrol, Diabnil, Duotrol, Dutrol, Eumet, Giclamide, Glibenclamide, Glibet, Glibson, Glifil, Glimsug, Glitrac, Gluconil, Glucored, Glucosafe, Glucotrac, Glutowin, Glybid, Glybonil, Glybovin, Glybovine, Glycurub, Glymep, Iscept, Pionorm, Sugatrol, Sugnil, Sugnl, Sugronil, Triglucored, Triglycomet

Similar Products:
Cycrin, Feldene, Abilify, Abhigra, Rulide, Antivert, Pyridium, Lozol, Algest, Domaspas, Ranitidine, Redome, Alleroff, Kaprolam, Iburin,

Also known as: Glibenclamide


This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.


Usual Adult Dose for Diabetes Type 2:

Doses provided as Benclamet-metformin -As Initial Therapy in Patients with Inadequate Glycemic Control on Diet and Exercise Alone: Starting dose: 1.25 mg-250 mg orally once a day -Consider a starting dose of 1.25 mg-250 mg orally twice a day for patients with fasting blood glucose (FBG) greater than 200 mg/dL or HbA1c greater than 9% Maintenance Dose: Increase in increments of 1.25 mg-250 mg per day every 2 weeks up to the minimum effective dose to achieve glycemic control Maximum Initial Dose: 10 mg-2000 mg per day -Patients with Inadequate Glycemic Control on a Benclamet (or another Sulfonylurea) and/or Metformin: Initial dose: 2.5 mg-500 mg or 5 mg-500 mg orally twice a day Maintenance Dose: Increase in increments of no more than 5 mg-500 mg to the minimum effective dose to achieve adequate blood glucose control Maximum Dose: 20 mg-2000 mg per day Comments: -Give with meals; 5 mg-500 mg dose should not be used as initial therapy due to an increased risk of hypoglycemia; initial doses should be conservative to avoid hypoglycemia largely due to Benclamet and gastrointestinal side effects largely due to metformin. -For patients who are switching to combination therapy, initial doses should not exceed the daily dose of Benclamet (or equivalent sulfonylurea) and metformin already being taken; the decision to switch to the nearest equivalent dose should be based on clinical judgement. -Addition of thiazolidinedione may be appropriate for patients not adequately controlled on Benclamet-metformin; in patients experiencing hypoglycemia, consider reducing the dose of the Benclamet component. -Monitor patients closely for signs and symptoms of hypoglycemia. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Detailed Benclamet/metformin dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A Benclamet overdose can cause life-threatening hypoglycemia.

Symptoms of severe hypoglycemia include extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure.


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( for more information if you do not have access to a take-back program.

Side effects

The most common side effects associated with Benclamet are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Benclamet in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving Benclamet.

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Third International Conference on the Management of Erectile Dysfunction: Linking Pathophysiology and Therapeutic Response. Interactions leading to a collision frequency that is an increasing (decreasing) function of ionic velocity are characterized by chord conductances that are decreasing (increasing) functions of field strength. What patients are reading about noninvasive prenatal testing: an evaluation of Internet content and implications for patient-centered care. Gametic and somatic tissue-specific heterogeneity of the expanded SCA1 CAG repeat in spinocerebellar ataxia type 1. An activated carbon substrate surface for laser desorption mass spectrometry. Our results show that the protein shape plays a significant role in the protein precipitation behavior. The present study has investigated the effects of the main electrospinning parameters on tensile and suture retention strength of polycaprolactone (PCL) scaffolds using response surface methodology. Human chromosome 3: high-resolution fluorescence in situ hybridization mapping of 40 unique NotI linking clones homologous to genes and cDNAs. Hyperinsulinemia and central adiposity: influence of chronic insulin therapy in type 1 diabetes. Current applications and future prospects of fine-needle aspiration biopsy of locoregional lymph nodes in the management of breast cancer.

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The preferred location is the elbow flection, in the cephalic or basilic veins. Education and training of complementary therapists: the role of higher education. The findings indicate that physiological methods to enhance heat transfer by the blood to the periphery within protective clothing provide an additional tool for increasing total and local human comfort in extreme environments. Being excluded a different chemistry between the stripe and the substrate, the influence of topography on the behaviour of endothelia cells was thus envisaged. It appears that the alleged insufficiency of breast milk volume after four to six months is most likely due to management errors such as introducing supplements and spacing nursing bouts at wide intervals, both of which reduce milk yield. In addition, the pKa values of cephradine, cephalexin, cefaclor, and cephapirin attributed to the deprotonation of either an amino group or a pyridinium group are reported, and the migration behavior of these cephalosporins in the pH range studied is quantitatively described.

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A novel method was used, positioning a neurosurgical patty in the middle meatus and assessing blue dye nasal spray absorption on a 4-point scale. Nonsteroidal Anti-inflammatory Drugs (NSAIDS) Inhibit the Growth and Reproduction of Chaetomium globosum and Other Fungi Associated with Water-Damaged Buildings. Quantitative assays of two genetic loci in a human lymphoblastoid cell line. Routine removals of internal fracture fixation implants were analyzed for demographic data and clinical details. Magnetic resonance spectroscopic evaluation of brain tissue metabolism after irradiation for pediatric brain tumors in long-term survivors: a report of two cases. Using noninvasive measurements of CO during exercise, we compared the prognostic value of peak CO and cardiac power to peak V(O(2)) in chronic heart failure patients. Coumarin induced acral skin necrosis associated with hereditary protein C deficiency. Furthermore, many of the features known to be associated with atypical depression, such as higher prevalence in women, higher prevalence of comorbid anxiety disorders, and younger age of onset, may be accounted for by the biological underpinnings of the disorder. Theoretical and clinical implications of these results are discussed, including the potential support for ToM-based interventions for early psychotic symptoms. Localization of protective 143/140 kDa antigens of Plasmodium knowlesi by the use of antibodies and ultracryomicrotomy.

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