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Betasemid (Furosemide)
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Betasemid

Betasemid is a loop diuretic (water pill) that prevents your body from absorbing too much salt. This allows the salt to instead be passed in your urine. Betasemid is used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome.

Other names for this medication:
Aldalix, Anfuramide, Ansemid, Betasemid, Foliront, Frusemide, Frusenex, Furantral, Furesis, Furetic, Furide, Furocot, Furosemide, Furovet, Furoxem, Furozenol, Fursemid, Furtenk, Fusix, Inclens, Intermed, Jufurix, Lasilacton, Lasilactone, Lasiletten, Lasilix, Salix, Vesix

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Also known as: Furosemide

Description

Lasix is an anthranilic acid derivative. Chemically, it is 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid. Frusemide is a white to off-white odourless crystalline powder. It is practically insoluble in water, sparingly soluble in alcohol, freely soluble in dilute alkali solutions and insoluble in dilute acids.

Lasix Tablets contain 40 mg frusemide. Inactive ingredients include lactose, starch - maize, silica - colloidal anhydrous, talc - purified, magnesium stearate, sunset yellow FCF and quinoline yellow aluminium lake.

Lasix M Tablets contain 20 mg frusemide. Inactive ingredients include lactose, starch - maize, silica - colloidal anhydrous, talc - purified and magnesium stearate.

Lasix Oral Solution contains 10 mg/mL frusemide. Inactive ingredients include sorbitol, glycerol, sodium hydroxide, methyl hydroxybenzoate, potassium sorbate, polysorbate 80, butylated hydroxytoluene, butylated hydroxyanisole, ethanol, tetrarome orange 987431, quinoline yellow, purified water.

Lasix 20 mg/2 mL; 40 mg/4 mL ampoules. Inactive ingredients include sodium chloride, sodium hydroxide and water for injections. Contains 0.16 mmol/mL of sodium.

Dosage

Adults. The usual initial daily dose is 20 to 80 mg given as a single dose. If the diuretic response to a single dose of 20 to 80 mg is not satisfactory, increase this dose by increments of 20 to 40 mg, not sooner than 6 to 8 hours after the previous dose, until the desired diuretic effect is obtained. This individually determined dose should be given once or twice (e.g. at 8 am and 2 pm) daily. The dose of Lasix may be carefully titrated up to 400 mg/day (except in advanced renal failure) in those patients with severe clinical oedematous states. The mobilisation of oedema may be most efficiently and safely accomplished by giving Lasix on 2 to 4 consecutive days each week.

When doses exceeding 80 mg/day are given for prolonged periods, careful clinical laboratory observations are particularly advisable.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling very thirsty or hot, heavy sweating, hot and dry skin, extreme weakness, or fainting.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Betasemid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Betasemid if you are allergic to furosemide, or:

if you are unable to urinate.

To make sure Betasemid is safe for you, tell your doctor if you have:

kidney disease; enlarged prostate, bladder obstruction, urination problems; cirrhosis or other liver disease; an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); high cholesterol or triglycerides (a type of fat in the blood); gout; lupus; a thyroid disorder; diabetes; or sulfa drug allergy.

Tell your doctor if you have an MRI (magnetic resonance imaging) or any type of scan using a radioactive dye that is injected into your veins. Both contrast dyes and furosemide can harm your kidneys.

It is not known whether Betasemid will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

Furosemide can pass into breast milk and may harm a nursing baby. This medicine may also slow breast milk production. Tell your doctor if you are breast-feeding a baby.

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miR-29a/b/c are important tumour suppressors and novel prognostic biomarkers of gliomas, and miR-29a/b/c and CDC42 are potential therapeutic candidates for malignant gliomas. Observations on vernier and stereo acuity with special reference to their relationship. Cardiac output was increased with isoflurane, but remained unchanged with halothane and enflurane. Influence of night-time protein and carbohydrate intake on appetite and cardiometabolic risk in sedentary overweight and obese women. Putative structural proteins, located in the N-terminal one-fourth of the polyprotein, include the capsid protein C (21 kDa) followed by two possible virion envelope proteins, E1 (31 kDa) and E2 (70 kDa), which are heavily modified by N-linked glycosylation. Prospective, nonrandomized study of previously healthy infants who underwent intubation and whose lungs were ventilated because of respiratory failure caused by RSV infection. Disseminated infection by Scedosporium prolificans: an emerging fatality among haematology patients. Interventional MR imaging for injection of sacroiliac joints in patients with sacroiliitis. However, finding the right drug and right patients has remained a serious problem. Furthermore, ubiquitous expression of dominant Lef-1 protein variants from transgenes revealed that zygotic Lef/Tcf activity is required for the ventroposterior development of Xenopus embryos.

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LPS administration resulted in a robust increase in IL-1R1 mRNA levels in the pituitary, adrenal gland and spleen of wild-type (WT) and CRH KO mice, but this elevation was attenuated in the pituitary and adrenal gland of CRH KO mice. Perivascular iron deposits are associated with protein nitration in cerebral experimental autoimmune encephalomyelitis. Weight, weight change since 25 years of age, body mass index, lean body mass and percent body fat, and nonspine fractures during 6.4 years of follow-up. The chemicals tested are nicotine, parathion, atropine, diisopropyl methylphosphonate, dimethyl methylphosphonate, dipinacolyl methylphosphonate, ethyl methylphosphonic acid, isopropyl methylphosphonic acid, methylphosphonic acid, and thiodiglycol. As has been determined using spectral-domain OCT, CT decreases with advancing age, especially after age 40. It was recently shown that p53-dependent apoptosis is promoted by homeodomain-interacting protein kinase-2 (HIPK2), which is known to bind p53 and induce its phosphorylation in promyelocytic leukemia protein nuclear bodies (PML-NBs). Relationship between malocclusion, orthodontic treatment, and tooth wear. A new approach of the meat inspection methods is only possible with the cooperation of the other EU member states and the people who are involved in the meat inspection.

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IC neurons in the GEPR exhibit significantly elevated response thresholds and broader tuning characteristics than normal. fumigatus growing under conditions allowing biofilm formation or with preformed biofilm. The paper describes a case of successful treatment in a patient with secondary multiple organ dysfunction (mainly hepatic and renal failure), by concurrently using different methods of efficent therapy (ultrahemodiafiltration, plasmapheresis) and infusion of the hepatic protectant heptral. Few were conducted with men alone, and most focused on behavioral and social psychological rather than morbidity outcomes. This approach provides synthetically versatile and densely functionalized 4-borylated 1,2-oxaborol-2(5H)-oles (vinyldiboronates) in a straightforward manner. Cell extracts were assayed for CAT activity by thin?layer chromatography. The separation in the acidic phosphate and the alkaline borate buffer generates a different pattern and only the combination of both buffer systems allows an appropriate assessment of sample complexity. In summary, the destruction of photoreceptor cells by the apoptotic process was the mechanism by which retinal degeneration was induced by MNU. Therefore, if patient is suffering from another type of hypertension like dry dystemperament of vessel wall, it surely requires another treatment approach for reducing vessel wall dryness.

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Methanolic extracts of Acacia nilotica and Retama raetam were used in this study. In two cases the isochromosome contained the same allele(s) as a normal transmitted chromosome 12, one paternal and one maternal in origin. The release of lysozyme and recombinant thrombocidin (rTC-1), an antibacterial protein derived from human blood platelets, from the gelatin-ChS gels in Dacron in phosphate-buffered saline at 37 degrees C was determined, and compared to the release from gelatin gels in Dacron and plain gelatin-ChS gels. The accuracy of US, barium radiology, and CT in detecting internal fistulae and abscesses was assessed by comparing results with intraoperative findings in 128 consecutive patients who underwent operation immediately after diagnostic workup. To study the relationship between carotid plaque morphology and the degree of stenosis on Duplex ultrasonography and symptoms. Notably, the Cd-induced melatonin synthesis was significantly impaired by treatment with either an H2 O2 production inhibitor (DPI) or an NO scavenger (cPTIO). To establish the frequency of very low maternal serum AFP and to differentiate congenital AFP deficiency from those diseases known to be associated with low AFP. Cotransfection of plasmids encoding PrV glycoproteins B (gB), gD, gH, and gL resulted in formation of polykaryocytes, as has been shown for homologous proteins of herpes simplex virus type 1 (HSV-1) (A.

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Antiarrhythmic therapy for the prevention of sudden cardiac death. A competitive radioimmunoassay for serum 7S fragment of type IV collagen (7S collagen) using a polyclonal antibody against 7S collagen and a sandwich enzyme immunoassay for serum central triple-helix of type IV collagen (IV collagen) using two monoclonal antibodies against the pepsin-solubilized type IV collagen may be used as diagnostic aids for liver fibrosis in clinical medicine. Anodization Mechanism on SiC Nanoparticle Reinforced Al Matrix Composites Produced by Power Metallurgy. To investigate the possibility that tyrosine phosphorylation of cellular proteins might play a role in GH receptor signaling, we have studied tyrosine phosphorylation induced by GH and by GH mutants in the human lymphocyte line IM-9, a homologous cell system which is known to respond to GH by increased proliferation. Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma. Strong immunoreactivity for p53 suggests the presence of mutated p53 in these cells as well. The isolation of colon cancer organ specific neoantigen by the use of the leukocyte adherence inhibition assay and monoclonal antibodies.

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Epigenetic factors and related small molecules have emerged to be strongly involved in autophagy process. Disordered N-Terminal Domain of Human Uracil DNA Glycosylase (hUNG2) Enhances DNA Translocation. Dose homogeneity constraints, rather than dosimetric coverage, were the limiting factors for all patient plans. Three-dimensional saline contrast hysterosonography and surface rendering of uterine cavity pathology. Myelography proves to be useful in posttraumatic spine diagnostics but in some cases does not render sufficient information, especially if the trauma superimposes previously existing pathological changes. Therefore, we developed a facile and scalable methodology for site-specific chemical ubiquitylation. The jet flow rate and jet configuration are relatively less important. There has been a significant improvement in the development of selective EGFR inhibitors with the use of a structure-based design approach employing a homology model of the EGFR kinase domain. Prostate cancer: combined FEC-PET/MRI improves diagnostic accuracy.

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An injection of h-rTFPI at a high dose (4 mg/kg of h-rTFPI or three doses of 1 mg/kg) significantly prevented the decrease of fibrinogen and factor VIII and the increase of fibrin/fibrinogen degradation products and glutamic-pyruvic transaminase in rats, while a single injection of 1 mg/kg of h-rTFPI or 250 U/kg of antithrombin did not significantly prevent intravascular coagulation. The increase in adolescent suicides has prompted the World Health Organization to set targets to reduce the incidence of deaths by the year 2000. Sixteen patients with DSM-IV depression and 19 matched controls participated. Five-year pulmonary autograft durability is excellent, although the risk of early failure may be increased. We discovered that PSR staining can also be visualized by fluorescence microscopy. Our study will provide useful information for investigating the sources of Salmonella infections, as well as selecting effective antibiotics for treatment. We carried out an in vivo experiment using a porcine liver to verify the effectiveness of our manipulator and model. Lumbar fusion rates for degenerative conditions increased from 2005 to 2006 with variation in operative procedures in relation to diagnoses. Our aim was to determine the impact of freezing, thawing, and subcutaneous transplantation on follicular development in grafted mouse ovaries. The expression levels of several genes involved in secondary wall formation and flowering were affected by the overexpression of the six PdMYBs in Arabidopsis.

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Is ADAMTS-13 deficiency specific for thrombotic thrombocytopenic purpura?. the use of FDC anti-tuberculosis therapy increases the risk for tuberculosis recurrence compared with using separate drug formulation. Hierarchical Rank Aggregation with Applications to Nanotoxicology. Because of its ruggedness, it can persist in the hospital setting and cause serious nosocomial infections. Application and efficacy of endotracheal tube of drug injection for postoperative patients.

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Regulation of proteoglycan synthesis by leukotriene d4 and epidermal growth factor in bronchial smooth muscle cells. This study investigated early electrocardiographic findings in relation to left ventricular (LV) function, extent and size of infarction, and microvascular injury in patients with acute myocardial infarction (MI) treated with percutaneous coronary intervention (PCI). QOA is a systematic means to confirm the applicability of clinical strategies developed from a single qualitative project, to dose of solu medrol im extend the repertoire of clinical interventions, and to evaluate clinical outcomes. In contrast, Delta frh mutants lacking the cytoplasmic F(420)-reducing hydrogenase (Frh) are severely affected in their ability to grow and make methane from methanol, and double Delta fpo/Delta frh mutants are completely unable to use this substrate. One corresponds to the crossover point and is similar for all recombinases of the family.

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An increase in circulating lymphocytes can be seen following infections such as infectious mononucleosis and pertussis, or in lymphoproliferative disorders such as acute and chronic lymphocytic leukemia. The presence of a complex congenital anomaly may warrant further evaluation with cross-sectional imaging to depict the anatomy and structure. In the absence of the substrate camphor, the P-450cam heme iron atom is hexacoordinate with the sulfur atom of Cys-357 providing one axial heme ligand and a water molecule or hydroxide ion providing the other axial ligand. Dental pulp cells attached and proliferated rapidly on collagen and gelatin, but chitosan did not properly support cell growth. The potential role of implantable cardioverter defibrillators (ICDs) in this group of patients has been the subject of increasing interest. The subjects were 185 vaccinated hospital workers and 450 unvaccinated city office workers. These results indicate that during pneumococcal pneumonia, IL-10 attenuates the proinflammatory cytokine response within the lungs, hampers effective clearance of the infection, and shortens survival.

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Off-time Pubertal Timing Predicts Physiological Reactivity to Post-puberty Interpersonal Stress. Bladder cancer (BC) is a major cause of mortality worldwide as it currently lacks fully reliable markers of disease outcome and effective molecular targets for therapy. The technique has potential for de novo diagnosis of CAD and as a complementary modality to angiography to assess the significance of given angiographic lesions. Of the two antigenically distinct toxins, Stx1 and Stx2, Stx2 is more firmly linked with the development of HUS. Prevalence of obstructive sleep apnoea in patients with coronary antibiotic classification of bactrim artery disease. This cross-sectional study was conducted in 2011 (January to December) in the pediatric intensive care of the Brazzaville University Hospital.

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