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Bexomer (Eszopiclone)
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Bexomer

Bexomer is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia. It is slightly effective for this use. Bexomer is the active dextrorotatory stereoisomer of Bexomer, and belongs to the class of drugs known as cyclopyrrolones. It is also classified as a therapeutic sedative hypnotic and pharmacological cyclopyrrolone.

Other names for this medication:
Bexomer, Eszopiclone, Fulnite, Zolnite, Zopimin, Zopipure

Similar Products:
Levothroid, Colospa, Motilium, Noroxin, Robaxin, Albenza, Lozol, Trileptal, Indanox, Dipal, Glimilex, Mbend, Zincoderm,

Also known as: Eszopiclone

Description

Bexomer (eszopiclone) is a sedative, also called a hypnotic. It affects chemicals in your brain that may be unbalanced in people with sleep problems (insomnia).

Bexomer is used to treat insomnia.

Bexomer causes relaxation to help you fall asleep and stay asleep.

Dosage

Do not take a dose of this drug unless you have time for a full night's sleep of at least 7 to 8 hours. If you have to wake up before that, you may have some memory loss and may have trouble safely doing any activity that requires alertness, such as driving or operating machinery.

This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as nausea, vomiting, flushing, stomach cramps, nervousness, shakiness) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.

When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.

As you get older, your sleep pattern may naturally change and your sleep may be interrupted several times during the night. Consult your doctor or pharmacist for ways to improve your sleep without medication, such as avoiding caffeine and alcohol close to bedtime, avoiding daytime naps, and going to bed at the same time each night.

Overdose

In clinical trials with Bexomer, one case of overdose with up to 36 mg of Bexomer was reported in which the subject fully recovered. Since commercial marketing began, spontaneous cases of Bexomer overdoses up to 270 mg (90 times the maximum recommended dose of Bexomer) have been reported, in which patients have recovered. Fatalities related to Bexomer overdoses were reported only in combination with other CNS drugs or alcohol.

exaggerations of the pharmacological effects noted in preclinical testing. Impairment of consciousness ranging from somnolence to coma has been described. Rare individual instances of fatal outcomes following overdose with racemic zopiclone have been reported in European postmarketing reports, most often associated with overdose with other CNS-depressant agents.

General symptomatic and supportive measures should be used along with immediate gastric lavage where appropriate. Intravenous fluids should be administered as needed. Flumazenil may be useful. As in all cases of drug overdose, respiration, pulse, blood pressure, and other appropriate signs should be monitored and general supportive measures employed. Hypotension and CNS depression should be monitored and treated by appropriate medical intervention. The value of dialysis in the treatment of overdosage has not been determined.

As with the management of all overdosage, the possibility of multiple drug ingestion should be considered. The physician may wish to consider contacting a poison control center for up-to-date information on the management of hypnotic drug product overdosage.

Storage

Store at 25 degrees C (77 degrees F); excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Bexomer are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

CNS depressant effects: Impaired alertness and motor coordination, including risk of morning impairment. Risk increases with dose. Caution patients taking 3 mg dose against driving and against activities requiring complete mental alertness during the morning after use.

Evaluate for Co-Morbid Diagnoses: Reevaluate if insomnia persists after 7 to 10 days of use.

Severe Anaphylactic/Anaphylactoid Reactions (angioedema and anaphylaxis have been reported): Do not rechallenge if such reactions occur.

Abnormal Thinking, Behavioral Changes (e.g., hallucinations), Complex Behaviors (e.g., sleep-driving): Immediately evaluate if occurs.

Worsening of Depression or Suicidal Thinking may occur: Prescribe the least number of tablets feasible to avoid intentional overdose.

Withdrawal Effects: symptoms may occur with rapid dose reduction or discontinuation.

Elderly Patients: Use lower dose due to impaired motor, cognitive performance and increased sensitivity.

Patients with hepatic impairment, impaired respiratory function, impaired drug metabolism or hemodynamic responses: Use with caution.

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