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Biocitral (Calcitriol)
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Biocitral

Biocitral is a form of vitamin D3. Vitamin D helps your body absorb calcium from the stomach. Biocitral is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people who have chronic kidney failure and are not receiving dialysis.

Other names for this medication:
Admax, Alcee, Alfabond, Alfacal, Alphadol, Apcical, Arachitol, Arcium, Aristrol, Biocitral, Bonetuf, Calbec, Calbory, Calcicare, Calcimet, Calcirol, Calcor, Calday, Caldikind, Calgel, Caltin, Calvical, Calzem, Carcal, Cholical, Citroj, Coecoral, Denscal, Duracal, Estovon, Fovit, Ikmag, Koncal, Kurecal, Lctrol, Nutribone, Osteobel, Ostriol, Qpcal, Riecal, Ritoca, Septriol, Sorvate, Statbone, Sunmic, Vezocal, Vitalpha

Similar Products:
Glyburide, Aceon, Luvox, Diamox, Duricef, Omnicef, Daklinza, Flomax, Tamiram, Tykast, Remens, Aridus, Udipan, Zelor, Clobate,

Also known as: Calcitriol

Description

Generic Biocitral is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Biocitral are intestine and bone. Generic Biocitral receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Biocitral may also act on the kidney and the parathyroid glands. Generic Biocitral is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Biocitral has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Biocitral, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Biocitral in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Biocitral produces other independent beneficial effects. Biocitral is also known as Calcitriol. Generic Biocitral treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Biocitral is Calcitriol. Brand name of Generic Biocitral is Biocitral.

Dosage

This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Biocitral. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Biocitral and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Biocitral are:

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Contraindications

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

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ICONOGRAPHIC COLLECTIONS OF THE COLLEGE DE MEDECINE DES HOPITAUX DE PARIS. Studies in experimental animals have shown that oxidative stress and hyperhomocyst(e)inemia culminate in abnormal vascular and endothelial regulation, functional nitric oxide deficiency, vascular hypertrophy, and atherosclerosis. Compound aggregation is a major reason for false positives in drug screening, and even soluble oligomers can interfere with structural and biochemical analyses. familiar hypercholesterolemia, sitosterolemia), but in most of the disorders the exact genetic cause remains unknown. On questioning and examination procedures in a supposed heart patient. Is marriage counseling feasible in Africa to prevent sickle-cell disease?. Adoption and implementation did not differ by diabetes prevalence or type of diabetes strategy. The first discovery in 1823 of what has become known as mediastinal teratoma is discussed. It is suggested that the pronounced lack of teeth in the maxillary anterior region is connected with deficient development of the premaxillary area of the nasopalatine canals and the incisive foramen.

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ON SOME ANATOMO-CLINICAL ASPECTS OF A DERMOID OF THE PONTO-CEREBELLAR ANGLE. Cytosine-arabinoside induced bradycardia in patient with non-Hodgkin lymphoma: a case report. Since ACE2 promotes the degradation of angiotensin II, a decrease in ACE2 activity could lead to the development of glomerular injury. The techniques used were the MTT assay, flow cytometry, real-time PCR to assess miR-199a expression, as also caspase-8 and caspase-9 activity in HepG2 cells treated with Propofol. The arteries, veins and their paracolic anastomoses distributed over ileocecal region, ascending colon and transverse colon were observed.

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A computer-assisted system allowing precise preoperative planning and real-time intraoperative image localization of surgical instruments is tested in a laboratory setup. A technique of cerebral protection by internal carotid artery (ICA) clamping with or without simultaneous external carotid artery (ECA) clamping was used to treat patients with proximal CCA stenosis by the retrograde direct carotid approach. The elimination of half-life was similar to that of the low dose. Men and women with vertebral fractures often have reduced vertebral size and bone mineral density (BMD). WNND is associated with considerable short- and long-term morbidity and mortality. Axillary hyperhidrosis is a common and distressing problem interfering with the life of affected individuals. The domain co-occurrence network was constructed for the human proteome based on PFAM domains in proteins. Data were collected via three methods: a review of study publications, study case report forms, and a questionnaire sent to the authors. Sarcomeric myofibrillar structures were not disrupted but tropomyosin was dissociated from the structures by the exogenous cofilin, and the IATMR-cofilin became localized in I-band regions.

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Cultural mediation and training of health care professionals: from cross-culture to co-discipline. Collecting prescriptions was the reason most cited for visiting the GP. Key features associated with the clinical, professional, organisational and normative dimensions were considered appropriate by the experts. Mutant nuo29.9 seems to accumulate the membrane arm of complex I and being devoid of the peripheral part. A generalized growth mixture model was used to identify trajectories of ADL disability across seven 18-month intervals. Changes in the management of infrarenal abdominal aortic aneurysm disease in Sweden. Using a continuous quality improvement process, the occupational health nurse and the EAP provider can establish a dynamic relationship that allows for growth beyond the original design and increased effectiveness of service to employees. Ensemble climate predictions using climate models and observational constraints. The expression of ACE2 receptor was the highest in the human lung microvascular endothelial cells, and lowest in the lymphatic endothelial cells. Thus after complete blockade of I(Kr) with dofetilide, the remaining I(Ks) current is homogeneous, as shown by an envelope of tails test.

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The toxic effects of paraquat on the anti-oxidant defense system of male albino rats were evaluated, after administering either a single dose (1.5 and 7.5 mg/kg of body weight) or continuous daily doses (same as above, i.e., 1.5 mg/kg and 7.5 mg/kg of body weight) for 3 and 7 days. Numerous reports of familial cardiac disorders associated with abnormalities of cutaneous pigmentation have appeared in the literature. Building on our prior research in this area, we developed a computer application that automatically converts text to pictures using natural language processing and computer graphics techniques. The relationship between analgesia and corticosteroid levels in rats. Three poor-quality cleavage stage embryos were transferred resulting in monochorionic triamniotic triplets and dichorionic diamniotic twins. We retrospectively reviewed the random serum lipid profiles obtained at cardiology clinic visits between May 2010 and November 2011 in patients who had undergone the Fontan procedure. Two groups of people, mainly employers and employees from enterprises, were covered in the survey, using quantitative (questionnaire) and qualitative (in-depth interview) methods. These maps appear to reorganise after damage to the peripheral parts of the sensory or motor systems, so that the cortical representation of undamaged structures expands at the expense of the damaged parts.

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