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Biokalm (Lorazepam)

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Biokalm, an antianxiety agent, has the chemical formula, 7-chloro-5-(o-chlorophenyl)-1,3- dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one. It is a nearly white powder almost insoluble in water. Each Biokalm tablet, to be taken orally, contains 0.5 mg, 1 mg, or 2 mg of Biokalm. The inactive ingredients present are lactose monohydrate, magnesium stearate, microcrystalline cellulose, and polacrilin potassium.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Clomid, Atarax, Precose, Amoxil, Flomax, Zantac, Clozaril, Mestinon, Indocycline, Nucoxia, Odozap, Panpep, Flodart,

Also known as: Lorazepam


Biokalm belongs to a class of medications called benzodiazepines. These medications work by boosting the activity of gamma-aminobutyric acid (GABA) within your body.

GABA is a neurotransmitter that transmits messages between cells in different parts of your body. Increasing GABA in the body results in a tranquilizing effect that reduces feelings of stress and anxiety.

How long does it take to work?

Benzodiazepines such as Biokalm are categorized based on how fast they work. Biokalm is classified as having a rapid to intermediate onset (start) of action. It begins to work right away after it’s taken, but its peak effect occurs within 1 to 1.5 hours.


Lorazepam is injected into a muscle or vein by a healthcare provider.

You may need to receive only one dose of lorazepam if your condition improves after the injection.

After the injection, you will be watched to make sure the medicine is working and does not cause harmful side effects.

Lorazepam injection is for single or occasional use. Ongoing use may be habit-forming or cause long-lasting withdrawal symptoms when you stop using the medicine.

Detailed Biokalm dosage information


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Biokalm can be fatal. Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma.


Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Biokalm is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Biokalm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use this medication if you have narrow-angle glaucoma, or if you are allergic to Biokalm or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), or oxazepam (Serax).

Before taking Biokalm, tell your doctor if you are allergic to any drugs, or if you have:


asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;

kidney or liver disease;

a history of depression or suicidal thoughts or behavior; or

a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

Biokalm can cause birth defects in an unborn baby. Do not use Biokalm without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. It is not known whether Biokalm passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The sedative effects of Biokalm may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking Biokalm. Do not give this medication to a child younger than 12 years old.

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The objective of this study was to investigate whether adiponectin might independently improve endothelial dysfunction in aorta isolated from high-fat-diet-induced obese. Her care has been instrumental in helping me finally live a normal life by keeping my psoriasis under control. The effect of oleic acid on neuron migration may be destined for the formation of synapses because the presence of oleic acid increased the expression of synaptotagmin and that of postsynaptic density protein (PDS-95), respectively markers of the pre- and postsynaptic compartments. Enamel extension rates in each of the three fossil taxa fell within the range of modern humans. We previously reported that combined treatment with tumor necrosis factor-alpha (TNF-alpha) and interferon-alpha (IFN-alpha) showed a synergistic antitumor effect via regulation of cell cycle progression in the S phase. Early-onset, Severe Chronic Obstructive Pulmonary Disease with Pulmonary Hypertension that was Likely Induced by Toluene Exposure. Relative levels of phosphorylated and total extracellular signal-regulated kinase, stress-activated protein kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase were measured in the hippocampus after 6, 12 or 24h of reperfusion using immunoblotting. A case of granulomatosis with polyangiitis associated with a p-ANCA pattern. The finding was reconfirmed by the result that fluoride-stimulated glucose-6-phosphatase activity was further enhanced by treatment with calphostin C (200 nmol/kg, i.p.), a specific and strong inhibitor of protein kinase C, but the change was small.

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Immune thrombocytopenic purpura (ITP) is an immune-mediated syndrome of unknown etiology characterized by the presence of autoantibodies against platelet membrane proteins. High-intensity training with a bi-directional bicycle pedal improves performance in mechanically unstable ankles--a prospective randomized study of 19 subjects. Antivenom therapy is the cornerstone of management for hemorrhagic or coagulopathic envenomation from pit vipers (with or without paralytic features), and for paralytic envenomation from coral snakes. Craniofacial anthropometric analysis in several types of chondrodysplasia. Established risk factors for depression in the general population are also markers of depression in PD. Extrapyramidal side effects induced by some selective serotonin reuptake inhibitors (SSRIs), i.e. Limb alignment, subluxation, and bone density relationship in the osteoarthritic varus knee. Platelets and white cells were incubated with Steen solution or buffer solution as control and stimulated with suitable agonists. Complete ureteral obstruction (CUTO) in the fetal kidney induces tubular and glomerular cysts, interstitial fibrosis, and halts renal development.

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From 8 days of age on, there was a progressive increase in enzymatic activity which was inversely correlated with the change in Michaelis-Menten constant. The spindle-shaped cells were closely apposed with focal intercellular contacts. Searches in PubMed, Google Scholar, and Web of Science resulted in 18 reports published before July 2015 that met the eligible criteria. Rabies virus neutralizing antibodies were detected in the sera of eight A. It is concluded that oblique ramus osteotomy has its good biological basis both in blood supply and cortex-to-cortex bone healing process. Significance of interfamiliar crisis for indication for appendectomy. The presence of the parasite in a sick individual from an endemic area does not mean that S.

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Experiments on a diverse of examples show that our results are much better than (challenging cases) or at least on par with (simple cases) the results of previous approaches.Stitching videos captured by hand-held mobile cameras can essentially enhance entertainment experience of ordinary users. A fuller characterization of exposure agents, such as peak levels and measurement of different particle sizes was recommended. The potential for repeated blood collection of 0.4-0.6 ml was facilitated by use of the present method at intervals of 7 days or more. PaCtr3 is not expressed in the grisea mutant confirming the assumption that the extension of lifespan is primarily caused by cellular copper limitation and a switch from a cytochrome oxidase (COX)-dependent to and alternative oxidase (AOX)-dependent respiration. In this study, we investigated the effects of migration inhibitory factor (rhMIF) on angiogenesis-related signaling cascades and apoptosis in human endothelial cells (ECs). The MOFs purified by the proposed method show high surface area and micropore volume, confirming the efficiency of the method.

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Unused segments of IMA and SV of each patient were cut into two rings of 3 mm length. Achievement of HBsAg loss remains the hallmark of chronic hepatitis B treatment. Clinical implementation of an automated planning system for gamma knife radiosurgery. A useful first step in this direction is to investigate the acoustic scattering of a new class of acoustic beams, known as helicoidal high-order Bessel beams, to improve the understanding of their scattering characteristics by an ultrasound contrast agent, which at present is very limited. Inpatient discharge data were requested from the respective departments of health for each state for three years (2007-2009).

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The vessels inside the mesentery on no occasion appeared infiltrated. We grouped the data by population characteristics including race, disability status, mental illness, demographics (age, era of service, rural location, and distance from care), sex identity, socioeconomic status, and homelessness, and created maps illustrating the evidence. Home monitoring limits asphyxia and may prevent death in infants thought to be at risk for recurrent apnea. However, extra-pair males did not differ from social mates in rTL, and accordingly there was also no difference between within- and extra-pair young (i.e. A computed tomography scan of the head was obtained, and the patient was transferred to our institution for neurosurgical evaluation and possible intervention of what was thought to be bilateral intracranial hemorrhages.

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Computed tomography (CT) showed irregular nodule in the right upper lobe. Sleep-apnea in patients with end-stage renal disease and objective results. A high incidence of instrument deformation and separation occurred with the air, high torque control and low torque control motors. The mechanism of action of 3,6-bis(2-piperidinoethoxy)acridine trihydrochloride (CL 246,738) in the potentiation of natural killer cells. These findings are important for the cultivation and processing of Chinese Flos Dendranthematis. These studies were performed in CHO T-REx cells stably transfected with a plasmid encoding the chimeric receptor and a novel assay was developed to study the effect of PCSK9 on the LDLR in these cells.

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The surgical patient experienced no complications and was asymptomatic with no recurrence at 2 years. There were 8 cases of isolated neck failure of which 3 occurred in the 62 patients who had no planned neck surgery, 0 in the 13 patients who had surgery for presumed residual (pathologically negative in 7). Hospital readmissions at the communitywide level: implications for case management. This paper outlines a range of state technology assessment activities, highlighting programs in Minnesota, Oregon, and Washington, and discusses the issues associated with state government involvement. Chiral pharmaceuticals: A review on their environmental occurrence and fate processes. Finally, creation of a global library that covers all the aspects of personalized medicines for different types of autoimmune disease was suggested. Over-expression of immune response genes seems to be a common feature of ER-negative sporadic and familial breast cancer and may be associated with good prognosis. We have examined the efficacy and safety of gemcitabine in patients with relapsed or resistant lymphoma.

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In a stable transfection system, dominant-negative mutants of myeloid differentiation factor 88 (MyD88) and interleukin-1 (IL-1) receptor-associated kinase 1 (IRAK-1) (MyD88-TIR and IRAK-DD, respectively) blocked Akt kinase activity in response to LPS and IL-1 beta. Nevertheless, few older people utilise primary oral healthcare services. A facile and efficient synthesis was developed to fabricate a 3D-porous LiNbO3 nanocomposite by microwave-induced auto-combustion. Migraine diagnosis was settled according to the International Classification of Headache Disorders-II diagnostic criteria. Expression of the reductase as a glutathionine S-transferase fusion protein in Escherichia coli cells was successful as judged from the size of the polypeptide band obtained on induction with isopropyl thio-beta-D-galactoside. Screenings for both ADHD and ODD and the provision of services that offer students more constructive coping alternatives to deal with stress in their intimate relationships are needed on university campuses. Prospective study of 100 individuals with TBI based on consecutive referrals for motor speech evaluations. This knowledge could prove critical in developing novel therapeutic approaches for the treatment of autoimmune diseases such as MS. The recurrence amount per unit dose was greater with small dose injection than with large dose injection. We also found a significant difference in overall survival (OS) between the two groups.

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This study is a brief quantitative analysis of the benefit provided by a clinical pharmacist in a multidisciplinary neurosurgical setting. Studies of TAVR in low-flow severe aortic stenosis patients have demonstrated that TAVR has a significant mortality benefit compared with medical therapy and a similar benefit compared with surgery. The results showed that Compounds 13, 16 and 17 displayed hepatoprotective effects. On normal isolated corneas (without contact lenses), the Ringer containing an excess of 4.8 mM NaCl significantly deswelled the corneas (-13.44 microns/hr), which contrasted with oxalate and oxamate containing Ringer solutions (1.17 and 1.33 micron/hr respectively). The impact of IA on islet transplantation has never been explored. After wide excision of the diseased mitral commissures, the posterior leaflet of the tricuspid valve was carefully checked, removed with its subvalvular apparatus, and transferred to the commissural area of the mitral valve. To our knowledge, this is the first report describing the application of melting curve analysis for genotyping of C. Introducing printed postpartum orders for measles-mumps-rubella vaccination: a qualitative study. We selected articles from a combination of the results of a MEDLINE search (1966-1996), a manual search of bibliographies, and contact with leading researchers.

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Although the improvement in ventricular function is a beta-blocker class effect, there are distinct differences in antiadrenergic activity and tolerability among the first-, second-, and third-generation agents. Soybean product intake prevented fasting and postload hyperglycemia and type 2 diabetes mellitus in men with a high BMI. The findings of our study indicate that the anti edematous effect of rhEPO could be mediated through an early inhibition of ERK phosphorylation after diffuse TBI. A randomised trial comparing 5-FU with 5-FU plus cisplatin in advanced pancreatic carcinoma. In acute and chronic complications, cross-section methods are superior because extraenteric lesions can be detected precisely. Clinic patients are referred to the clinic through the EHR and managed by a pharmacist under a CDTM protocol. These data confirmed that activated neutrophils and neutrophil-derived superoxide anions were implicated in lung injury after acute severe pancreatitis. Poor outcome of oesophageal adenocarcinoma after prior antireflux surgery. A slightly larger TST reading was seen with 10 TU than with 5 TU. To assess the feasibility of using recombinant adenovirus vectors to transduce the human lens epithelial cells (LECs) involved in posterior capsule opacification (PCO).

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Previous studies have found persistent overuse of imaging for clinical staging of men with low-risk prostate cancer. Data for pathological staging of radical prostatectomy specimens reported in the Section of Histopathology of a large tertiary care hospital in Pakistan were compared with sextant biopsy findings to determine whether clinically localized disease is actually localized pathologically. These findings suggest that the inhibition of NO biosynthesis leads to an increase of duodenal HCO3- secretion, partly mediated by the vagus nerves. In the present study we demonstrate that Ro 08-2750 binds to the NGF dimer thereby probably inducing a change in its conformation such that NGF cannot bind to p75(NTR) anymore. Chronic inhibition of COX-2 during pregnancy (gestation days 15-18) significantly increased neonatal mortality by preventing closure of the DA after birth, whereas acute COX-2 inhibition near the end of term (gestation day 18) constricted the fetal DA. Sequences are reported for a genomic segment encoding eight transfer RNAs, NADH dehydrogenase component 2 (ND2), and portions of NADH dehydrogenase component 1 (ND1) and cytochrome c oxidase subunit 1 (COI). Benzodiazepine treatment of many preparations, including cells expressing recombinant GABAA receptors, may elicit only desensitization, sequestration, or uncoupling, without a decline in receptor number.

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Selected early clinical trials utilizing these agents in combination with radiotherapy or chemoradiotherapy are discussed. The authors show that p38MAPK is involved in apoptosis, fibrosis and decreased left ventricle fractional shortening in mice overexpressing beta(2) adrenergic receptor but not beta(1) adrenergic receptor. Ultrasound-Assist Extrusion Methods for the Fabrication of Polymer Nanocomposites Based on Polypropylene/Multi-Wall Carbon Nanotubes. We provide evidence that PXR regulates a similar program of genes involved in xenobiotic metabolism in human liver. The hippocampal laminin matrix is dynamic and critical for neuronal survival. The enhancement of the molecular dynamics upon mixing with water, which in glass-forming systems implies a lower glass transition temperature (T g ), is considered a universal result is zyrtec a prescription drug of hydration. Between four and 10 GPs and/or PCG Board members attended each workshop.

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Liver disorders are the major manifestations of schistosomiasis mansoni. Leaf spot disease caused by Cercospora is responsible for crop and profitability losses in sugar beet crops in the US and worldwide. Depending on age, phase in the cell cycle, nutrition, and environmental factors, individual cells exhibit large metabolic diversity. Five hundred and seventeen neonates divided into groups with and without occurrence of nosocomial infection were included into the study. The second section looks at pre-defined strains and the re-production of full creep curves based on available data which is pertinent to the medication classification of levaquin aerospace industry where components are replaced before failure.

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Prospective study of all 53 patient referrals to a paediatric neurosurgical centre between April and November 1999 with a diagnosis of presumed shunt malfunction. Social skills differences in aggressive and non-aggressive male young offenders within an unfamiliar social situation. Association between Anthropometric Indices, Body Composition and Bone Parameters in Thai Female Adolescents. To evaluate phenylalanine plasma profile in preterm newborns fed different human milk diets. Ultrastructural observations on peritoneal exudate cells from the striped bass. This study provides a reference for the enantiomeric purity determination and resolution of some practical optically active mandelic acid and its analogs. The microbiology, epidemiology, clinical, and neurologic aspects of listerial infection and general aspects of the acquired immunodeficiency syndrome are discussed. Characterization of a highly pathogenic avian influenza H5N1 clade 2.3.4 virus isolated from a tree sparrow. The growing field of metabolomics has opened up new opportunities for prediction of type 2 diabetes (T2D) going beyond the classical biochemistry assays. Concurrent antitumor and bone-protective effects of everolimus in osteotropic breast cancer.

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The aim of this study was to evaluate C(2) and trough (C(0)) CsA concentrations as surrogate markers of area under the concentration-time curve (AUC) in stable, long-term heart transplant recipients receiving CsA alone or with diltiazem and/or ketoconazole. The aim of this study was to test whether the sweet flavour obtained with a low-energy sweetener (aspartame) or with sucrose have a different effect on DIT. Phylogenetic classification system of the genus Bacillus using fatty acid biomarkers embraces Bacillus phylogeny with physiological and biochemical charateristics. In the current paper, part II of the review, live vaccines, as well as vaccines for travelers and specific occupational groups, will be discussed. In the remaining 14 arteries CAG was judged necessary, in 11 arteries because DS assessed the internal carotid artery (ICA) as occluded, which was confirmed by CAG in 10 arteries.

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Rescue workers included construction workers, police officers, firefighters, emergency medical service technicians, or Urban Search and Rescue workers. Predictions of the maximum contact pressure have been made for an existing knee joint replacement in order to illustrate the present analysis in the design cycle. Lactosylceramide: effect of acyl chain structure on phase behavior and molecular packing. A close correlation was found between these two profiles, both being high in midvitellogenic follicles and low in postvitellogenic follicles collected during is methotrexate an immunosuppressant drug oocyte maturation. Advanced nano and microfabrication methods are key to the development of such structures, allowing one to tailor optical fields at the sub-wavelength scale, thereby optimizing excitation conditions for ultrasensitive detection. In June 1995, the Westchester County (New York) Department of Health (WCDOH) received reports from physicians who were treating patients for suspected HGE. Vietnam and France have conducted scientific exchanges since 1975, when Vietnam reunified.

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Static and dynamic human blood adsorption studies on polydimethylsiloxane, PDMS, and silicone rubber show that these materials are similar, but not identical, in their protein adsorption behavior. Organic lesions and metabolic disorders in arterial hypertension and the effect on them of hypotensive therapy. The pattern of trauma differed significantly between Stoke and Portland. Patient support and education for promoting adherence to highly active antiretroviral therapy for HIV/AIDS. Reduction Osteotomy versus Extensive Release on Clinical Outcome Measures in Simultaneous Bilateral Total Knee Arthroplasty.

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Little is known of the impact of acute right ventricular (RV) volume overload on RV function. Body surface mapping criteria for diagnosis of left ventricular hypertrophy associated with complete right bundle branch block. These genes are now isolated from human, mouse, chick, Xenopus and zebrafish and can be divided into three classes. Human Dental Pulp mobic 15 mg tabletki Cells Differentiate toward Neuronal Cells and Promote Neuroregeneration in Adult Organotypic Hippocampal Slices In Vitro. Times and slopes of rising and decreasing acceleration, values and and quality of steady acceleration are supervised online. Syncope: current knowledge, uncertainties and strategies for management optimisation in the emergency department. The patient died eight months postoperatively with massive multiple metastases to the liver. Cardiac regeneration may revolutionize treatment for heart failure but endogenous progenitor-derived cardiomyocytes in the adult mammalian heart are few and pre-existing adult cardiomyocytes divide only at very low rates. Our data suggest that cognitive impairments in OCD are not secondary to symptoms and therefore form a trait feature of the disorder.

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Adults with congenital heart disease (CHD) are at high risk for morbidity and mortality. Deficiency of Hageman factor (factor XII) in patients with the nephrotic syndrome. The ox-LDL from the fish diet group increased the diclofenac, L-NAME resistant relaxations to ACh compared to the control diet group suggesting the role of endothelium derived hyperpolarizing factor (EDHF). Fibroblast culture was performed to evaluate cell adhesion and proliferation on poly(ethylene glycol) (PEG) hydrogels crosslinked by a hydrolyzable polyrotaxane. Simplified external fixation for primary management of severe musculoskeletal injuries under war and peace time conditions. We also demonstrate that mature pollen accumulates a range of mature microRNAs, the class of small RNA most frequently involved in post-transcriptional regulation of endogenous gene expression. The aim of the present series of studies was what is 50 mg of tramadol to investigate what motivates undergraduate students and how their motivation changes during their degree course. Echocardiography should be performed as early as possible to establish a prompt diagnosis and management. This retrospective study was performed to find riskfactors for mortality and to construct a score that predict outcome for patients with peptic ulcer perforation.

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