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Biolar (Lorazepam)
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Biolar

Biolar is a drug used for treating anxiety. It is in the benzodiazepine family, the same family that includes Valium, Xanax, Klonopin, Dalmane, and others. It is thought that excessive activity of nerves in the brain may cause anxiety and other psychological disorders. Gamma-aminobutyric acid (GABA) is a neurotransmitter, a chemical that nerves in the brain use to send messages to one another. GABA reduces the activity of nerves in the brain. Biolar and other benzodiazepines may act by enhancing the effects of GABA in the brain. Because Biolar is removed from the blood more rapidly than many other benzodiazepines, there is less chance that Biolar concentrations in blood will reach high levels and become toxic. Biolar also has fewer interactions with other medications than most of the other benzodiazepines. The FDA approved Biolar in March 1999.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Maxalt, Zocor, Motilium, Xenical, Duricef, Famvir, Yasmin, Cetrose, Ezetrol, Periactin, Sayodol, Utamide, Rustin,

Also known as: Lorazepam

Description

Biolar belongs to a class of medications called benzodiazepines. These medications work by boosting the activity of gamma-aminobutyric acid (GABA) within your body.

GABA is a neurotransmitter that transmits messages between cells in different parts of your body. Increasing GABA in the body results in a tranquilizing effect that reduces feelings of stress and anxiety.

How long does it take to work?

Benzodiazepines such as Biolar are categorized based on how fast they work. Biolar is classified as having a rapid to intermediate onset (start) of action. It begins to work right away after it’s taken, but its peak effect occurs within 1 to 1.5 hours.

Dosage

When given intramuscularly, Biolar Injection, undiluted, should be injected deep in the muscle mass.

Injectable Biolar can be used with atropine sulfate, narcotic analgesics, other parenterally used analgesics, commonly used anesthetics, and muscle relaxants.

Immediately prior to intravenous use, Biolar Injection must be diluted with an equal volume of compatible solution. Contents should be mixed thoroughly by gently inverting the container repeatedly until a homogenous solution results. Do not shake vigorously, as this will result in air entrapment. When properly diluted, the drug may be injected directly into a vein or into the tubing of an existing intravenous infusion. The rate of injection should not exceed 2.0 mg per minute.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Do not use if solution is discolored or contains a precipitate.

Biolar Injection is compatible for dilution purposes with the following solutions: Sterile Water for Injection, USP; Sodium Chloride Injection, USP; 5% Dextrose Injection, USP.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Biolar can be fatal. Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma.

Storage

Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Biolar is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Biolar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid drinking alcohol within the first 1 or 2 days after you receive lorazepam injection. Dangerous side effects or death could occur.

Lorazepam can cause extreme drowsiness that may last for 24 to 48 hours after the injection. Older adults may feel sleepy for even longer.

Avoid driving or hazardous activity until the effects of lorazepam have worn off completely. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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Through the implementation of the Omnibus Budget Reconciliation Act of 1990, considerable experience in ambulatory DUR programs has been achieved. The object of the study was the assessment of the mortality risk for persons with a mental disorder in an unselected representative community sample assessed longitudinally. Football, fast cars, and cheerleading: adolescent gender norms, 1978-1989. Our aim was to investigate whether the appearance of the proteolytic phenotype had any correlation with the expression of H-ras and nm23-H1 genes in carcinoma of the uterine cervix. Pro-inflammatory cytokines induce in vitro hyperresponsiveness in normal airway smooth muscle via a mechanism involving intracellular calcium mobilization. Prophylactic corticosteroids in singleton preterm pregnancies accelerate lung maturation and reduce the incidence of respiratory complications.

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The major drawback is the additional time needed for the interventional procedure, and the equipment and personnel requirements. Because high-flow nasal cannula presents some advantages, it may be used instead of NIV in obese patients after cardiothoracic surgery. A theoretical formalism is elaborated to determine the acoustic field scattered from a finite cylindrical shell reinforced by a set of ribs with internal axisymmetric oscillators, the locations and properties of which can vary arbitrarily along the cylinder axis. These effects of NO may result in impairment of cartilage repair, by interfering with the extracellular matrix regulation of chondrocyte function. These constraints can in turn be related to the generalized forces conjugate to the motion of grains rolling over each other. Quantities which sensitize with respect to these delayed type reactions do not induce antibody formation detectable by a sensitive hemagglutination. FeNO is higher for the acute onset than non-acute, which may be useful to evaluate the control degree. The two commonest surgical options are transection of the nervus intermedius, and microvascular decompression of the nerve at the nerve root entry zone of the brainstem. However vocational rehabilitation significantly improves these limitations, which in turn help these patients to integrate into the society so as to function efficiently in their roles as parents, home makers and social beings. In conclusion, DM aggravates brain damage in cirrhosis patients.

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Magnetic resonance imaging of the temporomandibular joint (TMJ) was performed on two normal volunteer subjects and two symptomatic subjects using a 0.15 T resistive magnet. Here, we provide a comprehensive study of several biofunctionalization methods, including the layer-by-layer technique and both the gas-phase and liquid-phase silanizations, and we propose a new maleimide-based protocol for grafting a protein to a sensor covered by alumina. The results indicate that Asp and Asn supplementation in rats with high glycogen concentrations (fed state) further increased the glycogen concentration in the muscle, and decreased in vitro 2-deoxyglucose (a glucose analog) uptake by the muscle at maximal insulin concentrations. Visible light-induced transition metal-catalyzed transformations: beyond conventional photosensitizers. In the first study the changes in the thiamine-dependent enzyme erythrocyte transketolase (TK) which followed the administration of oral thiamine are described. Isosafrole and safrole also prevented bromotrichloromethane (BrCCl3)-induced hepatocyte cytotoxicity, whereas PBO was ineffective. RYT had higher pH levels, electrical conductivity, and organic and ammonium nitrogen content than YT.

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The renal lesions characteristic of tuberous sclerosis are angiomyolipoma and cysts, with the former considered to be more common. Flow cytometric assay for the evaluation of phagocytosis and oxidative burst of polymorphonuclear leukocytes and monocytes in myelodysplastic disorders. Antisera raised against hemolymph proteins were also used to identify cross reactive antigens/epitopes present in other tissues by Western blotting, as well as by in vivo ELISA. This study explores the influence of individual factors and social support on traumatic reactions in firefighters exposed to tragic events in the line of duty. Factors affecting outcome in free-tissue transfer in the elderly. In some blood vessels efferent to the renal corpuscles, hydrostatic pressure may be as high as in the afferent supply. Rates of nearly all local and systemic reactions were significantly lower among the MPHBL group than the Lederle group. Other studies with older groups of persons are needed to examine the stability of scores. Pathological examination in each case revealed cavernous angioma.

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Coal dust explosions (CDE) are one of the main threats to the occupational safety of coal miners. The care of older persons with diabetes mellitus: families and primary care physicians. The 3.0 A crystal structure of the vitamin B(12) RNA aptamer revealed an unusual tertiary structure that is rich in novel RNA structural motifs. This report demonstrates the feasibility, demand, and effective synergy of integrating on-site primary care services into HIV VCT in Haiti. Further studies revealed that the effects of HG- and RGI-rich pectins were dependent on pretreatment, which caused alterations in cell morphologies such as cell size and shape, focal adhesion, and the organization of actin filaments, suggesting that HG and RGI pectins exert synergistic effects on cell migration, likely through different ways. Impacts of river bank erosion on population displacement in the lower Brahmaputra (Jamuna) floodplain.

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Dietary and activity habits and other life style components are assessed by questionnaires, prior to, during, and after training. This paper describes a case of occupational asthma caused by samba wood dust. Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for apnea of prematurity. In revision total hip arthroplasty (THA), proximal femoral bone loss creates a challenge of achieving adequate stem fixation. They also were the commonest reasons for discontinuing treatment and reported as suspected ADRs. The cell death induced in a VR1-independent manner has the hallmark of apoptosis, whereas the cell death mediated by vanilloids binding to VR1 is seemingly necrotic. In intact transgenic animals expressing cameleons, fluorescence ratio changes accompanied muscular contraction, verifying detection of calcium transients.

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Especially in the field of anticancer therapy many efforts have been made to deliver drugs to specific tissues. Serum was assayed for nitric oxide (NO), lipid peroxidation, and antioxidant enzyme. Occurrence of diacylglyceryltrimethylhomoserines and major phospholipids in some plants. The limit of the method is mainly determined by the formation of adducts between triethylamine and some PL, namely, PE, monomethylphosphatidylethanolamine, phosphatidylethanolamine plasmalogens, and some lyso-PL. To assess the validity of a diagnostic protocol designed to predict the outcome of newborns of mothers suspected to have primary cytomegalovirus (CMV) infection during the first 4 months of pregnancy. Dynamic compressive strain inhibits nitric oxide synthesis by equine chondrocytes isolated from different areas of the cartilage surface.

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To improve our understanding of the drought tolerance of the three common European temperate forest tree species Norway spruce, silver fir and common beech, we tested the influence of climate and tree-specific traits on the inter and intrasite variability in drought responses of these species. The temporal maturational changes in composition and structure of the mineral phase were difficult to assess because of the continuous deposition of crystals throughout culturing. Despite the regional nature of the PWVPWI measurements, as opposed to the global PWVtonometry measurements, abdominal PWVPWI and carotid-femoral PWVtonometry values were found to be similar, with an average bias equal to 0.25 m/s. As vaccination antigens should induce an appropriate mucosal IgA immune response against H. This is the first report of inducing HIV-1 Nef-specific cytotoxic T lymphocytes by DNA vaccine. To investigate whether or not the gamma-aminobutyric acid GABA receptor subtype Alpha genes GABRA5 and GABRB3 are associated with childhood absence epilepsy CAE . They exert multiple physiological effects on higher animals as immunoadjuvants, activators of macrophages, pyrogens, antitumor agents, inducers of contractility of smooth muscle, and promoters of slow-wave sleep, as well as nonspecific protectors of animals against infection. An incubation of the cells with 25 or 50 microm of CPt at 37 degrees C caused apoptosis, which progressively increased during the 24-72 h treatment. The study proposed a clinical decision rule: In patients who have taken a deliberate overdose, but deny taking paracetamol or paracetamol containing compounds, who have a GCS of 15, understand English well, and have not taken excessive alcohol, there is no need to take blood for paracetamol estimation.

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Terson syndrome in a course of cerebral aneurysm--clinical assessment. Seleno compounds and glutathione peroxidase catalyzed decomposition of S-nitrosothiols. To analyze the relationship between plasma level of cortistatin(CST) and coronary heart disease(CHD) and the factors that influence the level of CST. Insulin-like growth factor 1-induced alterations in lumbospinal monoamine dynamics. Attitudes are one of the most important outcomes of medical education, but little is known about curricular influences on specific attitudes. If Helicobacter pylori infection could be controlled through improved socio-economic standards and possible development of a vaccine, and if anti-inflammatory drugs devoid of gastric side effects can be developed, peptic ulcer may become a less important health problem in the future.

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We confirmed that the swollen ciliary body with anterior rotation and supraciliary space caused transient angle-closure glaucoma in this patient with Vogt-Koyanagi-Harada syndrome. The most interesting result of analysis of B12 elements is that B12-independent isozymes of the methionine synthase and ribonucleotide reductase are regulated by B12 elements in bacteria that have both B12-dependent and B12-independent isozymes. Several genes had been identified to be associated with the pathogenesis of dextro-transposition of the great arteries (d-TGA). A specific statute governing assisted reproduction is one way vasotec iv dosing to regulate assisted reproduction. Rpf is required to resuscitate the growth of dormant Micrococcus luteus organisms, and its homologues may be involved in mycobacterial reactivation. These differences persisted after adjusting for baseline differences in client characteristics. Report on a meeting of a Regional Working Group on Psychosocial Aspects of Voluntary and Involuntary Childlessness, held in London (UK) on 10-12 December 1979. These results strongly suggest that glucocorticoids do not have a significant role in mediating the LPS-induced acute suppression of pulsatile LH secretion in orchidectomized rats.

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Dysfunctional attitudes may be a risk factor for the onset (but not the outcome) of episodes of moderately severe, typically comorbid, anxiety and depression found in primary care settings. The immunoreactive material was localized on the granular cores and diffusely in the axoplasm in both nerves. Veterans with PSUD have more severe problems along several dimensions and use more numerous and varied services than cefpodoxime brand name those with 1 SUD. However, the effects of regression to the mean will confound a simple analysis of the repeated measurements obtained before and after the cross-over. Consequently, three DEGs, LRAT, SLC7A11, and ITGA2, were selected for further analysis. The aim of this study was to determine the clinical significance of the preoperative serum CRP level in patients with stage IV colorectal cancer.

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