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Bolodol (Tramadol)

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Bolodol is an inexpensive drug used to treat moderate to severe pain in adults. This drug is more popular than comparable drugs. It is available in generic and brand versions. Bolodol is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Other names for this medication:
Acupain, Anazac, Armadol, Axedol, Bolodol, Cadol, Cosdol, Cradol, Dolmeri, Dolomed, Gemodol, Haledol, Ivydol, Mandol, Mydol, Novadol, Ospidol, Pentazen, Redimol, Siatram, Sigmadol, Soztram, Stemadol, Tacil, Tramacon, Tramadol, Tramalex, Tramasol, Tramatas, Tramataur, Tramoflex, Trandol, Trandy, Tromar, Trugesic, Unidol, Urogendo, Zamadol

Similar Products:
Reminyl, Maxalt, Nuvigil, Anafranil, Aristocort, Dramamine, Micardis, Prandin, Avelox, Plaquenil, Cefpodoxime, Oxifungol, Euphodol, Starzine, Viridium,

Also known as: Tramadol


Bolodol (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

Bolodol is used to treat moderate to severe pain in adults.

The extended-release form of tramadol (Bolodol ER) is for around-the-clock treatment of pain. Bolodol ER is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Bolodol ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Bolodol ER.

Never share Bolodol ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Bolodol ER.

Bolodol ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Bolodol ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Bolodol ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Bolodol ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Bolodol ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Bolodol-PM dosage information

Side effects

The most common side effects associated with Bolodol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how Bolodol ER will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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Breath samples were taken according to both classic (21 samples over 5 h) and simplified (11 samples) schedules. Evaluation of individual components by both activity determination and protein measurement showed decreased synovial fluid specific functional activity (activity per microgram protein) to the more marked in synovial fluids with profound depressions of complement activity. Mechanisms governing the differentiation of a serotonergic phenotype in culture. Nevertheless, money, and therefore profit, may be involved in some human organ transactions, and the buying and selling of organs for transplantation remains common in too many countries. For this reason, each clinician should recognize this entity in the differential diagnosis of PB-related asymptomatic chronic hepatic enzyme dysfunction. Peptide-polymer conjugates: from fundamental science to application. Immunocytochemical demonstration of heat shock protein 25 in the rat temporomandibular joint. We performed a total colonoscopy and intubation of the ileocecal valve that showed patchy deep ulcerations in the rectum with bleeding inflammatory pseudopolyps. With all the assistance put in place to help a person in the process of losing their autonomy, why a regression could be observed?. Bleeding rates according to several bleeding criteria within one trial illustrate that different bleeding definitions can lead to markedly different conclusions about the safety of an antithrombotic regimen.

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By contrast, desmocollin subtypes Dsc1 and Dsc3 have been detected only in certain stratified squamous epithelia, with the most conspicuous restriction of Dsc1 to epidermis and--remarkably, but unexplained--lymph nodes, and in certain carcinomas and cell lines derived therefrom. The first observed patient with this CMS was heteroallelic for the two epsilon-AChR subunit mutations epsilon1101insT and epsilon1293insG. The objective of this study was to determine the effects of varying nitrogen sources and concentrations upon glutamine synthetase and protease activities in Prevotella ruminicola strain B(1)4. The restoration frequency of a neo gene and the ratio of restored and not restored copies of this gene in genomic DNA of transformed clones was quantitatively estimated. No significant effects were observed in the renal concentration test, urinalysis, renal histochemistry or histology of a wide range of organs at any level of 1-NAA tested.

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The lymphatic system and allergy of the delayed type in its relation to so-called collagen diseases. Since adrenergic drugs are widely used in the clinical practice, our findings may have therapeutical implications. Based on motility, pigment production and automated Gram-positive identification (GPI Vitek card), four of these six VRE isolates were identified as Enterococcus gallinarum. PERFORMANCE AND PHYSIOLOGICAL INDICANTS OF ACTIVATION IN A VIGILANCE SITUATION. Despite optimal inhibition of these systems with drugs such as ACE inhibitors, beta-blockers, digoxin and, most recently, spironolactone, the mortality rate remains unacceptably high. The development of the fibrous process in the lungs was attended by marked reduction of the zinc content in the tissues of the viscera, plasma, and formed elements of the blood, as well as of corticosterone and testosterone in blood plasma.

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A method for the preparation in industrial conditions of infectious antigens from tick-borne encephalitis viruses for hemagglutination inhibition reactions. The predicted topologies of two variants (M51 and M518) are strikingly similar to CbiK and HemH, suggesting that we recreated duplication events that are believed to have created the bilobial chelatases. It may allow an early treatment of invasive fungal infection at incubation phase, but exposes patients to unnecessary antifungal treatments with subsequent costs and antifungal selection pressure. Parental histories of antisocial personality and illicit substance use disorders are associated with increased risk for cannabis use disorder onset in offspring, especially among females with maternal cannabis use disorder histories. Identification and characterization of the viral interaction determinant of the subgroup A avian leukosis virus receptor.

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The use of a photocopying process for erasing the background of photoscans and accentuating small differences in optical density. The sequence space of class A GPCRs reveals the key role of mutations at the level of the TM2 and TM5 proline residues in the evolution of class A GPCRs. Skin sparing mastectomy and immediate breast reconstruction: a review. Regulation of energy balance by leptin involves regulation of several proneuropeptides such as proTRH and proopiomelanocortin. Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis. Positron Annihilation measurement showed that after lower dose implantation, divacancies were formed, which coexisted with monovacancies.

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An improved technique of preparing primary cultures of isolated cells from adult frog kidney. The purpose of this case report is to describe the possible initial presentation of sarcoidosis as generalized prolonged pruritus. Glycolytic metabolic blood changes throughout the human menstrual cycle. Other data indicate that these drugs act centrally through the inhibition of cyclo-oxygenase activity. Here, we describe modifications in the assay designed to facilitate screening for mutants and to permit intracellular exposure of the gene instead of in vitro treatment.

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Radiographic assessments included tooth development, eruption patterns, and bone formation. Abnormal accumulation of tau as filamentous structures is a neuropathological hallmark of neurodegenerative diseases referred to as tauopathies. Responses of cats to sudden falls: an otolith-originating reflex assisting landing. The authors present the case of a newborn, born at gestational age of 29 weeks, who died at 11 days of life with hypoxic-ischaemic cerebral injuries as a consequence of maternal anaphylaxis following the administration of amoxicillin in the community setting. Mean treatment times were 16 months for bone transport and 9.8 months for compression-distraction. EGF receptor phosphorylation was required for full TRH-induced activation of mitogen-activated protein kinase (MAPK) and stimulation of specific transcriptional responses. Targeted delivery of lysosome-associated membrane proteins is important for lysosome stability and function. In contrast to the controls, no metastases could be observed in the axillary lymph nodes of the test animals. Purification and properties of proline reductase from Clostridium sticklandii. Human thyrotropin-releasing hormone (TRH)-associated peptide 3 (hTAP-3), one of the cryptic peptides resulting from the proteolytic processing of preproTRH to produce TRH, was measured in human plasma from normal, hyperthyroid, and hypothyroid subjects.

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Angiotensin-II also stimulates the tissue inhibitor of metalloproteinases-1 (TIMP-1) in a dose- and time-dependent manner via protein kinase-C as an intracellular signaling cascade in the Ac-HSC, and these effects are completely suppressed by ARB. Two study groups included 12 HIV-infected patients with ANS and 25 patients with syphilis and HIV co-infection (without ANS). Then the permeation rate of ketoprofen and indomethacin increased. Restless legs syndrome induced by quetiapine: report of seven cases and review of the literature. We report a child with this disorder who displayed a subacute onset of delirium, seizures, and autonomic instability. Cao vit gibbons do not suffer obvious costs in terms of feeding competition and reproductive success by living in bi-female groups, but within-group feeding competition may determine the upper the limit of cao vit gibbon group size to a maximum of two breeding females. To describe the control of an outbreak of infection and colonization with the New York/Japan methicillin-resistant Staphylococcus aureus (MRSA) clone in multiple healthcare facilities, and to demonstrate the importance of making an MRSA management policy involving molecular typing of MRSA into a statewide public health responsibility. We describe a 72-year-old man with atrial fibrillation having an AMI, in whom a massive intracoronary thrombus of the right coronary artery was successfully removed by aspiration via a thrombectomy catheter, achieving successful reperfusion with a complete resolution of ST-segment elevation. In contrast, the inactivation properties of Na(v)1.8 are entirely cold-resistant. Clustered receptors deactivated faster and desensitized slower than the diffuse receptors, because of decrease in the apparent affinity of GABA binding.

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Characterization of second order local image structure by a 6D vector (or jet) of Gaussian derivative measurements is considered. To facilitate comparison, the urease was immobilized by both diazo and glutaraldehyde coupling. However, the suppressor cells were removed by passage through nylon wool or by carbonyl iron treatment. Fine-needle aspiration of bone is a simple, reliable, and accurate diagnostic technique that can facilitate patient management and preoperative decision-making and/or avoid unnecessary invasive procedures for patients with primary or metastatic bone lesions. Trends in length of stay, functional outcomes, and discharge destination stratified by disease type for inpatient rehabilitation in Singapore community hospitals from 1996 to 2005. The lack of meter-diary agreement suggests that the real reason for monitoring is not understood by many patients, raising issues about motivation, perceived need to impress healthcare providers and denial of poor control. Nitric oxide (NO) has been shown to influence dopaminergic neurotransmission in the striatum.

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Size was evaluated by electron microscopy and photon correlation spectroscopy. This case report of a 35-year-old white woman, gravida O, may represent the 1st report of tubo-ovarian aspergillosis. The infant developed a solitary hepatic abscess with saprophytic organisms. This suggests that the fast skeletal muscle LCs may be evolved isoforms possessing the ability to associate tightly with a variety of MHC isoforms. Thus, we propose that the in vitro study of gene expression, using both natural variation and perturbations induced, for example, by RNA interference, might provide a rapid and effective method for complex trait dissection in many species, including humans. Cecal volvulus carried the greatest mortality, 30 per cent (3 of 10 patients), whereas sigmoidal volvulus had relatively low mortality rate of 7 per cent (1 or 15). First, a literature review was conducted to identify features for achieving integrated service delivery. Two nearly identical experiments were conducted to determine the effects of the coccidiostatic compound monensin on Polled Dorset lambs experimentally infected with oocysts of Eimeria ninakohlyakimovae. Glycerol disrupts tight junction-associated actin microfilaments, occludin, and microtubules in Sertoli cells. As underlying disease, chronic obstructive bronchitis resistant to therapy was reported.

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Intra-individual and inter-individual differences may be explained by local and global differences in passive and contractile myocardial properties. Nutrition science and policy research: implications for Mediterranean diets. A chimeric study of the molecular basis of affinity and selectivity of the kappa and the delta opioid receptors. Therapeutic effect of conivaptan bolus dosing in hyponatremic neurosurgical patients. Treatment options in paraneoplastic disorders of the peripheral nervous system. As indicated by IEF, the preparation consisted of two different P450 isoforms with pI-values of 5.9 and 6.2, which were named P450MS1 and P450MS2 respectively. Pancreatoduodenectomy was possible in only four of the 138 patients operated on, and one of them died postoperatively. VARIABILITY IN GRAIN COUNT/DNA RELATION IN MOUSE THYMOCYTES LABELLED WITH THYMIDINE. However, limitations in catheter technology and imaging of delivery have prevented this technique from being reliable and reproducible, and the only completed phase III study in GBM did not show a survival benefit for patients treated with an investigational therapeutic delivered via CED.

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RATE AT WHICH MUSCLE BECOMES JOINED TO SCLERA AFTER OPERATIONS OF RECESSION AND RESECTION. The Soa bitter-sensitivity and Prp salivary-protein loci map to distal mouse chromosome six. Recent evidence has also shown that XY embryos develop faster than their XX counterparts at very early stages of development, and it has been reported that SRY and ZFY are expressed in early human and murine embryos. The modifications consist of asymmetrical PCR amplification of the sequence of interest, electrophoresis with a higher concentration of acrylamide, and the analysis of the DNA fragments under u.v. Concerning the event of an LNG spill, a study was performed on the relationship between the distance at which the lower flammability limit (LFL) concentration occurs and that corresponding to the visible contour of LNG vapor clouds. A significant reduction in the growth rate, mainly characterized by cell cycle arrest in the G0-G1 phase, was also evidenced.

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Segregational behavior appeared to be linked to copy number and therefore indicated random distribution of copies to daughter cells. We construct estimates having the particular property that the derivative estimates correspond exactly to the corresponding derivatives of the curve estimate even under locally varying bandwidth choice. The case study utilizes sociological and historical perspectives to analyse primary historical data on the health of the three groups most affected by the Gold Coast railways: expatriate railway workers, African railway workers and African communities living both within and outside the immediate vicinity of the railways. Sanatorium treatment of children with tuberculosis associated with nonspecific lung diseases. Chemical specificity of the organized lipoprotein elaborations of the nerve cell. Using components developed by open-source electronics platforms, we have designed and tested a low-cost automated behavioral box to measure forelimb function in rats. The purpose of this retrospective study was to evaluate the results and prognostic factors affecting the outcome of osteochondral autografting (mosaicplasty) in articular cartilage defects of the knee joint. Similarities in CAHPS and HEDIS disparities across measures might reflect common structural factors, such as language services or provider incentives, affecting several measures simultaneously. Thus, the type III receptor protein may play a role in presenting TGF beta 2 to the type II receptor and increase responsiveness to TGF beta 2 to a level comparable to that of TGF beta 1. This study provides insights about the role of reproductive factors in relation to risk of pathway-based subgroups of ovarian cancer that with further confirmation may assist with the development of improved strategies for the prevention of these different tumor types.

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Cutting balloon angioplasty for intrastent restenosis treatment. Isolation of a novel strain of Planomicrobium chinense from diesel contaminated soil of tropical environment. CT scan suggested this to be an zebeta medication half life LV aneurysm although it did not have appearances typical of this on echocardiography. This assay has several advantages, including a wide working range, high sensitivity and good practicability. In 2002-2004, 15-30-year-old IDUs in Baltimore, Chicago, Los Angeles, New York, and Seattle were recruited through community outreach, advertising and coupon-based participant referrals. The mandible (Gegant-5) preserves a portion of the right mandibular corpus from the M1 distally to the socket for the dc mesially, and the age at death is estimated as 4.5-5.0 years. Production of human parathyroid hormone by recombinant Escherichia coli TG1 on synthetic medium.

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There have been studies regarding bone theolair 250 mg hond mineral density variations in the cervical and thoracolumbar spine, but bone mineral density variations in the lumbosacral spine have not been documented. Energy-dispersive diffraction with synchrotron radiation and a germanium detector. KURACHINSK MUD EXTRACT THERAPY OF THE INACTIVE PHASE OF RHEUMATISM IN CHILDREN. To compare IUI with timed intercourse in men receiving oral steroid therapy for the treatment of infertility associated with antisperm antibodies. Bordetella bronchiseptica infection in cats following contact with infected dogs. The pathogenic bacteria separated from the liver and kidney of diseased fish were identified through pure culture, artificial infection, automatic tests in bacteriology automatic identification, drug sensitive tests, morphometry, and physiological and biochemical determination. Virtual surgical planning has improved the preoperative assessment and, in conjunction with the OPS, the execution of orthognathic surgery. When a dual-biomarker strategy was applied, combining serum progesterone with hCG, specificity improved significantly, which suggests that a multiple biomarker strategy might help distinguish viable from nonviable pregnancies in early gestation. ICH12, capable of biodegrading gamma- HCH was isolated from HCH-contaminated soil.

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This work supports the incorporation into mathematical models of disease of the clinical intuition that the history of disease in an individual matters, and represents an advance over several prior simulation models that assume a constant rate of disease progression. Synthesis of (-)-neplanocin A analogues as potential antiviral agents. All biaxin brand emergency departments were telephoned, and senior emergency doctors were asked which specialty provided this service, and whether this was done routinely, often, or could be either specialty. The determination of the protein-protein interaction (PPI) networks has been the subject of extensive research. In patients with intractable fecal incontinence, conventional treatment is not always successful. Studies on the potential association of socioeconomic status with iodine supply and the risk for thyroid disorders from developed countries are sparse. Deviation of the adsorption characteristics of the studied purines from the Langmuir adsorption model was compensated by the fitness of Flory Huggins and El Awardy et al. The aim of this study was to determine the role of phosphorylated Akt (pAkt) in angiogenesis and its correlation with vascular endothelial growth factor (VEGF)-A in gastric adenocarcinoma. Impaired absorption of chlorpromazine in rats given trihexyphenidyl.

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Preliminary intramuscular administration of trypsin and chimotrypsin (10 mg/kg) to the animals had no effect on permeability of glucophage xr 750 mg precio the hemato-encephalic barrier for the antibiotics tested, except penicillin. These include increased macrophage activation and infiltration into the endometriotic implants themselves as well as the peritoneal cavity where the implants often develop. RECOVERY OF ORGANICS FROM A EUTROPHIC LAKE BY THE CARBON ADSORPTION TECHNIQUE. Attacks on humans by wild boar (Sus scrofa) are occasionally reported in rural areas of Turkey. Embolization of disc occluder of a Wada-Cutter mitral prosthesis with survival.

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These women should undergo aggressive bowel surgery only if it is part of an optimal surgical cytoreduction. The same is true when it is used as a palliative treatment in processes where access is difficult. Animals were then tested for seven weeks on the skilled forelimb reaching task to assess the profile of recovery. In this population of healthy postmenopausal women, serum concentrations of carotenoids declined with increasing age and body fat mass. The selected SNPs were then genotyped using a restriction fragment length polymorphism method applied to 711 healthy Chinese volunteers. after beginning of the stimulation, and in neurons with a high firing rate-by the 35 th-40 th min. Isolation and characterization of glycolipids from erythrocytes of human blood A (plus) and B (plus). Diastolic function in neonates after the arterial switch operation: effects of positive pressure ventilation and inspiratory time. The 2.5-kb fragment contained two orfs, orf1 and truncated orf2. This appears to be an increasing problem with the predicted cohort of returning veterans appearing both in the U.S.

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The search strategy will include the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and WHO International Clinical Trials Registry Platform (ICTRP) search portal. It is concluded, that the carbachol-induced rise in the basal sphincter pressure is not dependent on an increase in serum gastrin, but probably attributable to either direct cholinergic stimulation of the receptors or a cholinergically enhanced sensitivity of the receptors for gastrin. This case study highlights the potential of hypoglycaemia for permanent deleterious effects on brain structure and albendazole 400mg tablet price memory function. There were no significant differences in LIN in any of the groups treated with SASP, in which remarkably reduced sperm motion was detected by the other parameters. It was possibly related to elevated level of osteoblast differentiation. Risk and resilience in the context of child maltreatment: the way forward.

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Our method is based on the use of animal tissues as biological containers, inside which the spermatic suspensions are included. Can endoscopic balloon dilation for primary obstructive megaureter be effective in a long-term follow-up?. Calcemia, phosphoremia and alkaline phosphatasemia in the healing process of experimental fractures under the influence of nor-androstenolone decanoate. In contrast, use of antidepressants has been associated with increased risks of hypertension, preeclampsia, and bleeding. The present case is of interest in that it occurred in a young, obese woman after she lost 18.2 kg (40 lb) in eight weeks. Administration of an antibody raised against TGF-beta to glomerulonephritic rats suppresses glomerular matrix production and prevents matrix accumulation in the injured glomeruli.

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