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Calosto (Calcitriol)
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Calosto

Calosto is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis. Systemic Calosto is FDA indicated to control hypocalcemia in patients on chronic renal dialysis, secondary hyperparathyroidism in those with chronic kidney disease not yet on dialysis, and hypocalcemia in patients with hypoparathyroidism and pseudohypoparathyroidism.

Other names for this medication:
Alfacal, Aristrol, Bonetuf, Calday, Caldikind, Caldix, Calotec, Caltin, Calvical, Citroj, Devita, Estovon, Ikmag, Koncal, Kurecal, Osteobel, Primacal, Qpcal, Rical, Ritoca, Rockbon, Rolsical, Septriol, Solbiocal, Sorvate, Statbone, Vezocal

Similar Products:
Paxil, Vermox, Ceftin, Minocin, Nimotop, Keflex, Elavil, Rocaltrol, Effexor, Albenza, Inclens, Epicure, Osalka, Gadopril, Tenoclor,

Also known as: Calcitriol

Description

Generic Calosto is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Calosto are intestine and bone. Generic Calosto receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Calosto may also act on the kidney and the parathyroid glands. Generic Calosto is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Calosto has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Calosto, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Calosto in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Calosto produces other independent beneficial effects. Calosto is also known as Calcitriol. Generic Calosto treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Calosto is Calcitriol. Brand name of Generic Calosto is Calosto.

Dosage

This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Calosto. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Calosto and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Calosto are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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To compare the dosing requirements and international normalized ratios (INRs) associated with two bioequivalent crystalline warfarin sodium products in patients with chronic atrial fibrillation. Synthesis and evaluation of optical and PET GLP-1 peptide analogues for GLP-1R imaging. aureus is a pyogenic bacterium that elicits recruitment of polymorphonuclear leukocytes (neutrophils) to the site of infection. Dual recordings from the apical dendrites and somata of mitral cells show that LLDs are generated in the distal portion of the apical dendrite, most likely in the glomerulus. We discuss outcomes after umbilical cord blood (UCB) transplantation (UCBT) for patients with acute myeloid leukemia (AML) and compare these outcomes to results after transplantation of other allogeneic graft sources. CneF solution at two different doses (36 and 72 mg/kg, based on carbohydrate concentration) was administered intraperitoneally 2 h before bacterial inoculation in the prevention groups and simultaneously with the appearance of clinical signs in the therapeutic groups. Spread of the Brazilian epidemic clone of a multiresistant MRSA in two cities in Argentina. The two domains are connected by a 17 residue long beta-strand and form a common interface. The vascularized pedicled nasoseptal flap (PNSF) represents a successful option for reconstruction of large skull base defects after expanded endoscopic endonasal approaches (EEA). The as-synthesized ZrO2 NCs (cubic or monoclinic) are small in size (3-10 nm), yet aggregated.

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Changes simulating molluscum contagiosum in the epidermis of keratoacanthoma and of some papillary neoplasms of the lower lip and skin. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the motility of human decidual endometrial stromal cells: possible effect on embryo implantation and pregnancy. Data were transferred from Qlikview to Excel and SPSS for statistical analysis. Promoting smoking cessation should be given utmost priority in clinical practice, and we offer practical strategies to facilitate this. A nematode species belonging to the genus Cosmocephalus was collected from the stomach of 2 common gulls, Larus canus.

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We found that NicK was required for association of HelP and PcrA with ICEBs1 DNA. ELECTROPHYSIOLOGICAL STUDIES OF THE HIPPOCAMPUS IN MAN WITH AVERAGED RESPONSE COMPUTATIONS. Within-group changes in burnout levels over time were analyzed using repeated-measures analysis of variance (ANOVA). Expression of denV in XP-F cells resulted in enhanced HCR of a UV-damaged reporter but did not affect UV sensitivity. Ascites is the most common expression of decompensated liver disease. In the other cases the lesions, generally unilateral, were extremely discrete.

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Histamine H3-receptor activation inhibits dopamine synthesis in rat striatum. Availability of iodised table salt in the UK - is it likely to influence population iodine intake?. However, a bony defect in the cribriform plate and a submucosal nasoseptal collection of cerebrospinal fluid behind an intact septal nasal mucosa were detected in computerized tomography and magnetic resonance imaging studies. Bipolar resections of the prostate were performed using Plasma-Kinetic Tissue Management System (Gyrus Medical Ltd., UK). Rotational and centrifugal distortion constants have been measured for one conformer of each of the species and for its -COOD isotopologue, leading to the experimental determination of the coordinates of the carboxyl hydrogen atom. Another arginine-rich protein, protamine also did not significantly stimulate immunoglobulin production.

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The results extend our knowledge of mood-cognition relations and have important implications for understanding the social cognitive consequences of positive mood states. The vascular pool of TFPI is released into the circulation after intravenous and subcutaneous administration of both UFH and LMWH. 13C and 1H NMR study of cellulose metabolism by Fibrobacter succinogenes S85. Arterial-venous oxygen content difference (A-VDeltaO2) and partial oxygen pressure index (Pvo2/Pao2, the ratio of oxygen tension in femoral vein blood to that in femoral artery blood) were measured before and during isoflurane or sevoflurane anesthesia in 16 diabetic and 22 nondiabetic patients. Disrupted mitochondrial electron transport function increases expression of anti-apoptotic bcl-2 and bcl-X(L) proteins in SH-SY5Y neuroblastoma and in Parkinson disease cybrid cells through oxidative stress. Polymerase chain reaction-mediated genotyping of Hortaea werneckii, causative agent of tinea nigra. The remaining 8 patients did not receive anticoagulation therapy, and went straight to treatment with thrombectomy and administration of tPA. In all groups of exposed rats, an altered frequency discrimination of the tonal stimuli was observed, in comparison with controls, at 70dB SPL. Medical education for pain and addiction: making progress toward answering a need. Assay of cis- and trans-o-hydroxycinnamic acids in sweetclover extracts.

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These observations provide new insights into the pathogenesis of hepatitis C and may offer new opportunities for therapeutic intervention. Head and neck keloid: treatment by core excision and delayed intralesional injection of steroid. This paper describes a novel and generic event detection algorithm applicable to signals from tri-axial accelerometers placed on the foot, ankle, shank or waist. Octameric enolase from the hyperthermophilic bacterium Thermotoga theophylline er tab 400mg maritima: purification, characterization, and image processing. Proceedings: Procainamide and phenytoin: a comparison of two antiarrhythmic drugs. Both required decompression of all the compartments following early clinical diagnosis and measurements of the intra-compartmental pressures. In total, sphere packings of 90 different types have been found. Endothelial dysfunction has been described with ageing but the mechanisms responsible have not been clearly elucidated and might be different from one vessel to the other.

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TREATMENT OF BRONCHIAL SUPERINFECTION OUTBREAKS IN CHRONIC BRONCHITIS PATIENTS WITH PENIMEPICYCLINE. Disruptions of ORFs YGR256w, YGR272c, YGR273c, YGR275w and YGR276c were carried out using the disruption marker kanMX4 flanked by short homology regions, whereas ORF YGR255c was inactivated with a long flanking homology (LFH) disruption cassette (Wach et al., 1994). Many different approaches have been developed for TCI, which have the potential to is dramamine an over the counter drug be effective, easy-to-use and painless methods of vaccination. Many studies have been conducted to try to abrogate those changes and so preserve peritoneal function. Many women at risk for HIV infection are still not using condoms. By maximizing the radiation force-induced vibration of scatterers in the focal region, the resolution of the ultrasound beam can be recovered after aberration defocusing.

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Distribution of Clostridium perfringens epsilon toxin in the brains of acutely intoxicated mice and its effect upon glial cells. Boron imaging is essential when considering boron neutron capture therapy as an option for treating cancerous tumors. No differences regarding the presence and extent of epidural fibrosis between the symptomatic and asymptomatic patients could be demonstrated with contrast-enhanced magnetic resonance imaging. This study aimed to employ OCT to evaluate four different resin-based materials including a coating containing glass-ionomer filler and calcium, a giomer, and two fluoride-releasing self-etch resins. This article presents an overview of human sexual response and the changes that occur in that response following SCI. However, low efficiency of gene transfer has often represented one of the major limitations of this technique. This initial examination of PV loops from a single-ventricle decapod crustacean demonstrates the utility of this technique to further elucidate the cardiac mechanics and energetics of this system, and in particular during times of physiological stress. Comparison of different intraocular pressure measurement techniques in normal eyes, post surface and post lamellar refractive surgery. We present the case of a 62-year-old woman with an advanced metastatic lung tumor that required palliative debulking.

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CLINICAL AND HISTOPATHOLOGICAL FINDINGS IN ACUTE SYSTEMIC LUPUS ERYTHEMATOSUS. Gcn5 Modulates the Cellular Response to Oxidative Stress and Histone Deacetylase Inhibition. In in vitro competition assays, when LIS1 is added first, DCX competes with LIS1 in its binding to microtubules, but when DCX is added prior to the addition of LIS1 it enhances the binding of LIS1 to microtubules. THE WATERHOUSE-FREDERICHSEN SYNDROME IN A 5-WEEK-OLD INFANT: HEMORRHAGIC NECROSIS OF THE ADRENAL GLANDS. Organic spirocyclic initiators for the ring-expansion polymerization of beta-lactones. The patient group also had higher levels of depression and anxiety than the control groups. Here we show that, in the absence of spleen and lymph nodes, the expression of homeostatic chemokines in the lung is essential for local B and T cell responses to influenza and for the development and organization of inducible bronchus-associated lymphoid tissue (iBALT).

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On the understanding of apoplectiform hemorrhage of the soft palate. Consecutive patients with breast hypertrophy completed the Health Utilities Index Mark 2, the Health Utilities Index Mark 3, and the Breast Reduction Assessment Value and Outcomes instruments (the Short Form 36, the Multidimensional Body-Self Rating Questionnaire Appearance Assessment, and the Breast-Related Symptom Questionnaire) at 1 week and 1 day before surgery and at 1, 6, and 12 months after surgery. CVBP is simple and very effective at re-warming hypothermic animals and may also reverse coagulopathy more quickly. In present day devices, ventricular sensing, extensive programmability, and large surface electrodes are general features. AGENESIS OF ONE OF THE PRINCIPAL VEINS OF THE LEG (APROPOS OF 5 CASES). Endiandrin A, a potent glucocorticoid receptor binder isolated from the Australian plant Endiandra anthropophagorum. The Pediatric AIDS Clinical Trials Group Protocol (PACTG) 316 trial evaluated the effectiveness of the addition of intrapartum/neonatal nevirapine in reducing MTCT in women already receiving antiretroviral prophylaxis. Physician and care teams will need to familiarize themselves with the tools their patients are using cost of 100mg lopressor and provide guidance and support for their use.

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Pharmacognostic study of the sprouts of potato Solanum tuberosum L. Anaemia in pregnancy: Plasmodium falciparum infection is an important cause in primigravidae in Hoima district, western Uganda. Results suggest two types of coalescence behavior, fast coalescence at low surface coverages that are independent of ionic strength and slow coalescence at high coverage. The importance of these reflex patterns in disturbances of micturition is discussed. Comparison of the shear bond strength of brackets using the led curing light and plasma arc curing light: polymerization time. Subsequently, stimulus control acquired by components of the compound stimuli was determined by brief test probes in which the colors and forms separately, and in novel combinations, appeared on the display screen. Polyarthralgia or severe haemorrhage can also be part of the clinical presentation. We demonstrate that TGIF interacts with the corepressor carboxyl terminus-binding how to give albendazole oral suspension ip protein (CtBP) via this motif. Both patulin (1 to 2 mug/egg) and the reaction mixture between patulin and cysteine (15 to 150 mug of patulin equivalents) were teratogenic to the chicken embryo. These results could represent an forward step in the clinical study of human gestational diabetes mellitus and their macrosomia babies, which may suffer some metabolic disease in their later life.

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