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Clarinex

Clarinex is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.

Other names for this medication:
Alerdain, Alerta, Allerdain, Allerde, Allergesic, Antialer, Biomon, Dazit, Delorta, Descare, Desent, Deslor, Desloratadine, Desloriv, Desnova, Dilora, Lorday, Loreta, Nelora, Neoloridin, Nucope, Otrivin, Reditabs, Rodera, Tastylora, Veromon

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Also known as: Desloratadine

Description

Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Dosage

Take this medicine only as directed. Do not take more of it and do not take it more often than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of side effects.

Not taking over-the-counter antihistamines and decongestants while taking desloratadine and pseudoephedrine combination.

When taking desloratadine and pseudoephedrine extended-release tablet:

Swallow it whole. Do not crush, break, or chew before swallowing.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release tablets [12 hour]): For nasal congestion or rhinorrhea Adults and teenagers—Oral, one tablet (2.5 milligrams desloratadine, 120 milligrams pseudoephedrine) two times a day 12 hours apart, taken with or without a meal Children 4 years of age and older—Use and dose must be determined by your doctor. Children and infants up to 4 years of age—Use is not recommended .

For oral dosage form (extended-release tablets [24 hour]): For nasal congestion or rhinorrhea Adults and teenagers—Oral, one tablet (5 milligrams desloratadine, 240 milligrams pseudoephedrine) daily, taken with or without a meal Children 4 years of age and older—Use and dose must be determined by your doctor. Children and infants up to 4 years of age—Use is not recommended .

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose may cause anxiety, trouble sleeping, headache, vomiting, thirst, muscle weakness, fast or pounding heartbeats, hallucinations, shallow breathing, or a seizure.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Clarinex Reditabs dosage information

Side effects

The most common side effects associated with Clarinex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The elderly are usually more sensitive to the effects of this medicine, especially if it contains:

Antihistamines—Confusion, difficult or painful urination, dizziness, drowsiness, feeling faint, or dryness of mouth, nose, or throat may be more likely to occur in elderly patients. Also, nightmares or unusual excitement, nervousness, restlessness, or irritability may be more likely to occur in the elderly taking antihistamines. Decongestants (e.g., ephedrine, phenylephrine, pseudoephedrine—Confusion, hallucinations, drowsiness, or convulsions (seizures) may be more likely to occur in the elderly, who are usually more sensitive to the effects of this medicine. Also, increases in blood pressure may be more likely to occur in elderly persons taking decongestants.

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These preliminary results have implications in understanding the etiology of motion sickness and may provide outcome measures to be used in treating motion sickness. Retinoid receptors cause distortion of the retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter. Use of D-dimer to exclude upper extremity deep venous thrombosis. Using a panel of murine cells that are variably configured with respect to the human IFNABR-alpha/beta subunits, we provide evidence that an additional component(s) encoded on human chromosome 21 is required to confer high affinity binding and IFN-inducible growth inhibition to cells that express the alpha and beta subunits of the IFNABR. A case of neonatal alloimmune thrombocytopenia due to fetomaternal incompatibility against the platelet-specific antigen Zwb (PlA2) is described.

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Receivingregular breast cancer screenings aids in the early detection and treatment of breast cancer. A total of 105 fetuses were studied, 56 from mothers who smoked during pregnancy and 49 from those who did not. Rapid pulmonary vein (PV) activity has been shown to maintain paroxysmal atrial fibrillation (AF). The increase in BDNF mRNA in DHPG-stimulated cells, which peaked by 12h after DHPG exposure, was attenuated by the mGluR5 inhibitor MPEP, but not by the mGluR1 inhibitor CPCCOEt. To evaluate the efficacy and tolerability of evolocumab when used in combination with a moderate- vs high-intensity statin. Pericardial effusion as presentation form of giant cell arteritis. Theoretical construction in the sociology of health: a reflection on its trajectory. The present study deals with attempts to deliver cyclosporin A into the deeper skin and some of the fundamental reasons why this proves so difficult. In general, responding during extinction was less likely with the mechanical apparatus when the reinforcer was absent and more likely with the computer program.

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It is therefore critical that primary care providers be prepared to identify and determine appropriate treatment options for patients presenting with substance misuse. To promote discussions, previously unpublished data, that are rather confounding, are presented and possible explanation provided on how these may fit into our current model. Reaction between 4-formyl-2-methoxyphenyl 4,5-dichloroisothiazole-3-carboxylate with various aromatic amines led to azomethins 2-7 formation. Prospective studies are needed to establish optimal therapeutic approaches in carefully selected low-volume mCRPC patients. No bactrim dose in renal disease gene for lipid biosynthesis but a single gene encoding a patatin-like protein likely for lipid mobilization was identified based on the selection criterion.

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The numbers of viable organisms from 15 clinical isolates each of Staphylococcus aureus, Escherichia coli, and Pseudomonas species were counted before and after incubation in the four solutions. Histopatholgical examination results of liver, pancreas and kidney were normal in general. Uterine estrogen receptor in rats during pubescence and the estrous cycle. Assisted reproductive technologies have multiplied their rate of occurrence in the last two decades. Liver failure in parenteral nutrition-dependent children with short bowel syndrome. These data support the hypothesis that the bulk of Tic110 extends into the chloroplast stroma and suggest that the domain forms a docking site for preproteins as they emerge from the Tic translocon. First, despite the low prevalence of each of the three obstetrical complications, all are associated with increased risks of adverse perinatal and infant outcomes, as well as neurodevelopmental deficits. Based upon this hypothesis, the proposed pituitary function diagnostic scheme could be used to test for endogenous GH secretagogue adequacy, as well as pituitary secretory capacity. Decline in cognitive function and elder mistreatment: findings from the Chicago Health and Aging Project. Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice.

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To study whether nephron sparing surgery is suitable or not for the operation for renal cell carcinoma (RCC) by examining the style of the existence and proliferative potential of satellite tumor lesions (STL). laparoscopic ureterolysis is effective and well tolerated in most cases of ureteral endometriosis. Some concentrations of stearylamine as a component of the phospholipid layer may fully compensate the surface charge of the glass capillary and can reduce the liposomes adsorption. We placed a HeRO device in a 67-year-old woman with end-stage renal disease and 2 months later, it was being used for hemodialysis. patient case mix, staffing, policy of discharge from the PACU etc. iNO causes dose-related increases in NO metabolites in the circulation as well as lung fluid, as evidenced by TA analysis, showing NO delivery to these compartments. Major conformational changes occur during the transition from an initiation complex to an elongation complex by T7 RNA polymerase. As part of a study to identify the characteristics of cord blood cells, we examined their morphological features by electron microscopy.

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