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Cordarone (Amiodarone)
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Cordarone

Cordarone is an antiarrhythmic. It works by blocking various receptors and channels in your heart, which play a major part in your heart's electrical activity. Cordarone slows down the electrical activity to help your heartbeat stay in a normal 'sinus' rhythm.

Other names for this medication:
Amiobal, Amiocar, Amiodacore, Amiodaron, Amiodarona, Amiogamma, Amiotach, Amirone, Ancaron, Ancoron, Cardilor, Cardiron, Corbionax, Cordalin, Cordan, Cordarex, Coronal, Coronax, Coronovo, Daritmin, Diarona, Escodaron, Eurythmic, Miocor, Nodis, Novarona, Opacorden, Pacerone, Pacet, Rhythmiodarone, Rithmik, Ritmocardyl, Rivodaron, Rivodarone, Sedacoron, Trangorex

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Also known as: Amiodarone

Description

Cordarone is an antiarrhythmic. It works by stabilizing the heart rhythm in conditions in which the heart is beating too fast or in an irregular rhythm. Generic name of Cordarone is Amiodarone. Cordarone is also known as Amiodarone, Pacerone. Brand name of Cordarone is Cordarone.

Dosage

This section provides information on the proper use of a number of products that contain amiodarone. It may not be specific to Cordarone. Please read with care.

You will receive your first dose of this medicine in the hospital. Your doctor will watch you closely after you take this medicine to make sure you do not have any serious side effects.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Do not miss any doses. It may also take 1 to 3 weeks before your body responds to this medicine.

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

You may take this medicine with or without food, but take it the same way each time.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For ventricular arrhythmias: Adults—At first, 800 to 1600 milligrams (mg) per day taken in divided doses. Your doctor may adjust your dose as needed and tolerated. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Cordarone and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cordarone dosage information

Side effects

The most common side effects associated with Cordarone are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Cordarone if you are allergic to Cordarone components. Do not take Cordarone if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Cordarone if you have complete, second degree, third degree, or severe sinoatrial heart block, an abnormally slow heartbeat, or shock due to serious heart problems, or if you have had fainting due to slow heartbeat (except if you have a pacemaker). Do not take Cordarone if you are taking cisapride, dofetilide, an H1 antagonist (eg, astemizole, loratadine, terfenadine), an HIV protease inhibitor (eg, ritonavir), a phosphodiesterase type 5 inhibitors (eg, vardenafil), or a streptogramin (eg, dalfopristin, quinupristin). Lab tests, including electrocardiogram (ECG), chest x-rays, lung tests, liver tests, thyroid tests, and eye exams, may be performed to monitor your progress. Be careful with Cordarone if you have allergies to medicines, foods, or other substances. Use Cordarone with great care in case you want to undergo an operation (dental or any other). Avoid alcohol. Avoid machine driving. Try to protect your skin from the sunlight. Do not stop taking Cordarone suddenly.

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PaCO(2), PaO(2), 6-min walking distance (6MWD), respiratory muscle function, FEV(1), vital capacity, and sleep efficiency (time asleep as a percentage of total time in bed) were used as outcome measures. The current study investigates the statistical correspondence of ERP tomography and fMRI within the common activity volume and time range in a complex visual language task. Sinoaortic denervation does not prevent differential Pavlovian conditioning of bradycardia in rabbits. The data showed that application of TTX at low doses (12.5-50 nM), which are far less than those needed for blocking action potential conduction, produced a significant elevation of mechanical threshold in the paw for foot withdrawals, a sign of reduced allodynic behaviors. A spike in a sensory neurone elicits a short-latency depolarising postsynaptic potential (PSP) in posterior rotator and adductor motor neurones whose amplitude is enhanced by hyperpolarising current injected into the motor neurone. At the medial site a decrease of the load bearing area and the pressure can be registered. Active celiac disease was characterized by distortions in cytokine expression by T lymphocytes, with highly significant increases of IFN-gamma and IL-10 but no concomitant increases in tumor necrosis factor alpha, transforming growth factor beta1, or IL-2 and no induction of IL-4.

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The perceptual effects of interphase gap duration in cochlear implant stimulation. TNF signalling to NF-kappaB and to its target genes such as IkappaBalpha seemed to be mostly intact in E1A/Ras-transformed cells. Accumulation, elimination, and speciation of cadmium and zinc in mussels, Mytilus edulis, in the natural environment. Combined assessment of glutamine and 2-deoxyglucose accumulation improves the ex vivo identification of macrophage activation states. Treatment is therefore carried out with the best results when done by a specialized team in specialized hospitals. Ischemic preconditioning coupled with nicorandil administration might provide protection for minimally invasive direct coronary bypass. We tested the hypothesis that delaying onset of hyperventilation will prevent severe (periodic) epileptiform EEG and hyperdynamic response. The increase in expression and activation of pp125FAK in metastatic PCa tissues was also corroborated by our findings in human PCa cell lines. At that time, methoxsalen still decreased in vivo covalent binding measured per whole liver, and permitted a faster recovery of hepatic glutathione.

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Mice injected with hemin significantly attenuated MCD-induced steatohepatitis and increased HO-1 protein and activity. Due to the potential for catastrophic neurotraumas and cervical spine injuries in sport, the sports health care professional must take proper measures to prevent such injuries. A novel bimediator amperometric sensor for electrocatalytic oxidation of gallic acid and reduction of hydrogen peroxide. We provide the first direct experimental evidence for dry adhesion of gecko setae by van der Waals forces, and reject the use of mechanisms relying on high surface polarity, including capillary adhesion. This defect allows an influx of ions, particularly potassium, which initiates an inflammatory reaction in the bladder wall, which incites the symptoms described above. Because glycosylation plays important roles in the folding, trafficking, and function of various Kv channels, we focused on the N-glycosylation of Kv12.2.

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