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Detrusitol (Tolterodine)

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Detrusitol is in a class of medications called antimuscarinics. It works by relaxing the bladder muscles preventing bladder contraction. Detrusitol is used treat overactive bladder (a condition in which the bladder muscles contract uncontrollably and cause frequent urination, urgent need to urinate, and inability to control urination).

Other names for this medication:
Bapter, Concys, Detrusitol, Dezrolala, Flochek, Roliten, Terol, Tolter, Tolterodine, Uftol, Uridin, Urotel

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Also known as: Tolterodine


Detrusitol (tolterodine) reduces spasms of the bladder muscles.

Detrusitol is a prescription medicine used to treat symptoms of overactive bladder in adults, including:

urge urinary incontinence: a strong need to urinate with leaking or wetting accidents; urgency: a strong need to urinate right away; or frequency: urinating often.

Detrusitol LA capsules did not help the symptoms of overactive bladder when studied in children.


Detrusitol can be taken in form of tablets, liquid pills, chewable pills, drops which should be taken by mouth. Take Detrusitol tablets orally with or without food. Do not crush or chew it. Take Detrusitol at the same time with water. If you want to achieve most effective results do not stop taking Detrusitol suddenly.


If you overdose Detrusitol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Detrusitol overdosage: feeling drowsy, blurred vision, dry eyes, coprostasis, dry mouth.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

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The most common side effects associated with Detrusitol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

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Changes in blood ammonia levels induced by electro-stimulation of the hypothalamus in rabbits. Contributions of ultrasound beyond clinical data in assessing inflammatory disease activity in rheumatoid arthritis: current insights and future prospects. The link residues (L815 and K816) provide main chain hydrogen bonds to N806 and a side chain hydrogen bond to the V804 carbonyl and thus stabilize the conformation of loop a. We evaluated the effectiveness of wound bed preparation by MDT in CLI patients who had undergone mid-foot amputation. Here we analyzed the nuclear distribution of the transcriptional coactivators CREB-binding protein (CBP)/p300 in situ by confocal laser scanning microscopy, and in vivo complex formation by coimmunoprecipitation. Therefore, halogenated chemicals exhibit different actions, i.e. Follicular and scarring disorders in skin of color: presentation and management. Influence of aquatic humus on the bioavailability of chlorinated micropollutants in Atlantic salmon. Using this analysis it is found that equal distribution of training patterns among the processors is not the optimal way to allocate the patterns even when the training set is an integer multiple of the number of processors. Scc1/Mcd1 is a component of the cohesin complex that plays an essential role in sister chromatid cohesion in eukaryote cells.

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This intracranial complication of suppurative otitis media which has become rare since the use of antibiotics, still raises diagnostic and therapeutic problems. All three compounds inhibited the growth of the hormone-dependent MCF-7 and hormone-independent MDA-MB 231 breast cancer line only at relatively high concentrations. Verteporfin inhibits growth of human glioma in vitro without light activation. Fifteen hours after placement of a lumbar drain she developed pure alexia and color agnosia caused by left lateral sinus thrombosis with hemorrhagic infarction in the posterior inferior left temporal lobe. The extent of the inhibitory response caused by alpha2-adrenoceptor agonists was related to the receptor density in clonal cell lines derived from the transfected parental HEK-7 cells. Validated questionnaires were used to investigate the presence of migraine, anxiety, and depression (Zung Self-Rating Anxiety and Depression scales), sleep quality (Pittsburgh Sleep Quality Index), and RLS severity (International RLS scale). Combined treatment with LY 300164 (2 mg/kg) and diazepam (0.3125-1.25 mg/kg) resulted in the clear-cut anticonvulsive activity. Over the long term, both techniques are safe and effective in restoring hearing and improving quality of life.

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At age 17 years, micturition disturbances were reported infrequently and few subjects wanted medical help. Although our understanding of the cellular properties of mammalian neurons is increasing rapidly, the computational function of their elaborate dendritic trees is still mysterious. Bright field microscopy and atomic force microscopy were used to morphologically characterize the aggregates size and form. The antianginal effect index was an increase of treadmill exercise duration (sec) as compared with placebo, the concentration and effect were measured in points 0, 1, 3, and 7 hours after administration, in some patients, investigations were conducted 12 and 24 hours. It has altered the therapeutic landscape for patients with symptomatic ventricular tachycardia or cardiac arrest. The remaining two clones did not correspond to known, previously sequenced organisms. The 6-min walk test (WT) and right-sided heart catheterization were performed at baseline, after three months on epoprostenol and thereafter once a year. The leading hypothesis is that high modularity evolves under multiple goals, which are decomposable to subproblems, as well as under the evolutionary constraint that selection prefers sparse links in a network. In the present study, we aimed to investigate the effect of MUFAs on the lipid organization and skin lipid barrier using an in vitro model membrane system, the stratum corneum substitute (SCS), mimicking the SC lipid composition and organization.

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To study whether the common ICF categories have different meaning for the two populations the Rasch model for dichotomous response option was used. SSRIs increase risk of blood transfusion in patients admitted for hip surgery. The investigation at this time was characterized by poor quality of B mode and color Doppler. Symptom development and virus accumulation of the cDNA derived viruses and parental viruses were identical. Stimulated shedding of vascular cell adhesion molecule dostinex reviews 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17). The low toxicity and widespread occurrence of OA in plants suggest a potential for the development of the triterpene or their derivatives as a new antiulcer drug. However, the correlation between antithrombotic and haemorrhagic effects of LHN-1 was the same as that of conventional heparin. In a period from January 1, 1990 to December 31, 2000, among 1,560 patients, we found 17 patients with DNM according with selection criteria. The Bristow and Latarjet procedures have become popular among orthopaedic surgeons thanks to the development of new instruments that allow the use of arthroscopic techniques to treat cases of glenohumeral instability with bone defects or capsular deficiency. We also developed a theoretical model for the drying mixtures based on dynamical density functional theory, which gave excellent quantitative agreement with the simulations for the polymer-polymer mixtures and qualitatively predicted the observed polymer-on-top or colloid-on-top structures for the colloid-polymer mixtures.

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Advantages include inert titanium alloy, which is stronger than the average femoral shaft, a recessed end of the nail, reaming to only 13 mm, and a quadrilateral shape. To establish the intra- and inter-rater reliability of composite finger flexion (CFF), and to compare this with goniometry. Findings demonstrated that two different complexes can be simultaneously present in solution involving, respectively, the inclusion of econazole monochloro-phenyl group within the host cavity from the primary hydroxyl side of the cyclodextrin cavity, or that of the other phenyl group through the opposite side of the cavity. Data were extracted from the Surveillance, Epidemiology and End Results-Medicare registry for patients with esophageal cancer who underwent esophagectomy between 2006 and 2009. The presence of a vascular anomaly suggests that capillaries, veins, arteries, and/or lymphatic vessels have demonstrated abnormal development and growth. Significant cellulose-pectin interactions in plant cell walls have been reported recently based on 2D 13C solid-state NMR spectra of intact cell walls, but how these interactions affect cell growth has not been probed. The deduced amino acid sequence of this clone predicts a 460-aa protein with a consensus NAD(P)H binding motif within the amino terminus. DC-based vaccines are normally generated using a standard 8day DC protocol (SDDC). Natural analogues (D, C2, and VII) of actinomycin inhibit Grb2 SH2 domain binding with phosphopeptide-derived from Shc in vitro and in intracellular system.

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In rupture of the cysts into the bile ducts echinococcectomy was combined with cleansing and drainage of the ducts: retrograde drainage after Abu proved to be the best method. To report the effects of ECT in 5 patients with metastatic malignant melanoma. Although some doses of each D2 partial agonist either increased (notably SDZ 208-911) or decreased (notably SDZ 208-912) the level of cocaine-appropriate responding engendered by low to intermediate doses of cocaine, none of the drugs reduced the percentage of cocaine-appropriate responding engendered by low to intermediate doses of cocaine, none of the drugs reduced the percentage of cocaine-appropriate responses engendered by 1.0 mg/kg cocaine. This investigation considered the trade-off between potential gains from testing more questions with fewer patients versus how often a factorial trial might arrive at an incorrect conclusion. Modulation of cutaneous inflammation induced by ticks in contrasting phenotypes of infestation in bovines.

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It is of clinical relevance to distinguish between complete hydatidiform mole and partial hydatidiform mole to predict prognosis of recurrency of molar pregnancy and the risk of the development of malign and metastatic gestational trophoblastic disease. A novel viral lineage distantly related to herpesviruses discovered within fish genome sequence data. Infection with the Santa Lucia strain showed a mean prepatent period of 16 days (range 6-21 days), whereas infection with the wild FCC-4 strain resulted in a 24-day prepatent period. Molecular monitoring of minimal residual disease in acute promyelocytic leukemia by the polymerase chain reaction assay for the PML/RAR alpha (retinoic acid receptor-alpha) fusion transcript in patients treated with all-trans retinoic acid followed by chemotherapy. Other reasons for screening comprise attempts to avoid endocrine morbidity and possibly forthcoming problems from malignant transformation, as well as attempts to identify and treat gene carriers with a clinically overt disease. Negligible clinical effects of thalidomide in patients with myelofibrosis with myeloid metaplasia. The medical records of patients who underwent total colpocleisis with high levator plication between August 1, 1988, and December 31, 2000, were retrospectively reviewed. At all three episodes, EEG was not indicative for status epilepticus, but in the acute episode it showed slowing of background activity emphasized on one side. A histopathological feature considered indicative of ulcerative colitis (UC) is the so-called basal lymphoid aggregates.

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Rational design of potent and selective permethrin medication EGFR tyrosine kinase inhibitors as anticancer agents. To use this technique to answer questions of regulation in heterogeneous populations of cells in the brain, it must be combined with other procedures allowing for the identification of functional subgroups of neurons. Our aim is to project the HIV estimates by taking into account general interventions for susceptibles and additional interventions, such as targeted interventions among high risk groups, provision of anti-retroviral therapy, and behavior change among HIV-positive individuals. An adequately powered intervention trial using screening requires a feasibility study establishing recruitment rates and dedicated, funded staff assistance. Comparison of visual and computerized estrous detection and evaluation of influencing factors. The hypothesis examined in the present article is that, while single dosing with a beta-blocker may cause acute bronchoconstriction, chronic dosing may afford putative beneficial effects including attenuated airway hyperresponsiveness. However, the insights from molecular biology technology may well open up more challenges in a variety of clinical situations.

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