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Hinate (Clobetasol)

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Hinate is available only for topical use in various forms including cream, ointment, and shampoo. This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use.

Other names for this medication:
Agiclob, Betanate, Clobadis, Clobate, Clobecos, Cloberis, Clobesym, Clobetamil, Clobetasol, Clobevate, Clobex, Clobezine, Clobin, Clobquad, Clomax, Clonate, Cloriv, Clotof, Cosvate, Covate, Cutivate, Cvate, Etavone, Kloryl, Magclo, Miconit, Salyco, Steriderm, Topisal

Similar Products:
Bystolic, Nolvadex, Flonase, Priligy, Requip, Suprax, Calan, Lopressor, Microzide, Lipigan, Worteen, Serectil, Bonestat, Petrox, Aleez, Norflol, Azicine,

Also known as: Clobetasol


Clobetasol is a highly potent steroid that helps reduce inflammation in the body.

Hinate (for the skin) is used to treat inflammation and itching caused by plaque psoriasis or skin conditions that respond to steroid medication.


This section provides information on the proper use of a number of products that contain clobetasol. It may not be specific to Hinate E. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

This medicine is for use on the skin only. Do not get it into your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

To help clear up your skin or scalp problem completely, it is very important that you keep using this medicine for the full time of treatment. Do not miss any doses.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor first before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

Do not use this medicine on the face, groin, or underarms, or if you have skin thinning, unless directed to do so by your doctor.

To use the cream, foam, gel, lotion, ointment, or spray:

Wash your hands with soap and water before and after using this medicine. Apply or spray a thin layer of this medicine to the affected area of the skin. Rub it in gently. With the lotion, protect the skin from water, clothing, or anything that causes rubbing until the medicine has dried. Also, shake the lotion well before using it. With the foam, do not dispense directly from the can into your hands, unless the hands are the affected area. Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor. Do not use Clobex® spray or Impoyz™ cream for more than 2 weeks unless your doctor told you to.

To use the foam, scalp solution, or shampoo:

Wash your hands with soap and water before and after using this medicine. Apply a thin layer of this medicine to the affected area of the scalp. Rub it in gently. Do not cover the scalp (eg, shower cap, bathing cap) while it is being treated. With the shampoo, do not wet your hair before using it. And if the shampoo gets on any part of your body other than your scalp, rinse the area well with water. Do not use the shampoo for more than 4 weeks, and the foam and scalp solution for more than 2 weeks unless your doctor told you to.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For redness, itching, and swelling of the skin: For topical dosage forms (cream, gel, or ointment): Adults—Apply to the affected area of the skin 2 times per day. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 12 years of age—Use is not recommended. For topical dosage form (lotion): Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. For plaque psoriasis: For topical dosage form (cream): Impoyz™: Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. Hinate®: Adults and children older than 16 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 16 years of age—Use is not recommended. For topical dosage form (foam): Adults—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (spray): Adults—Spray directly to the affected area of the skin 2 times per day. Children—Use is not recommended. For scalp problems: For topical dosage forms (foam or scalp solution): Adults—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (shampoo): Adults—Apply to the affected area of the scalp once a day. Children—Use is not recommended.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

High doses or long-term use of Hinate can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Hinate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of clobetasol topical cream, foam, gel, ointment, or scalp solution in children 12 years of age and older. However, because of this medicine's toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using this medicine, follow your doctor's instructions very carefully. Safety and efficacy have not been established in children younger than 12 years of age and the use of clobetasol topical cream, foam, gel, ointment, or scalp solution is not recommended. The safety and efficacy of clobetasol topical lotion, shampoo, or spray have not been established in children and use is not recommended.

Appropriate studies have not been performed on the relationship of age to the effects of Impoyz™ cream in the pediatric population. Safety and efficacy have not been established and use in children is not recommended.

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The present study describes the states of almost half of the amino acid residues of alpha1-acid glycoprotein, a knowledge important for the construction of a preliminary three-dimensional model of this conjugated protein. In conclusion, efficient delivery of proteins modified with galactose to the liver will be achieved by controlling both the galactose density on the protein surface and the administered dose. As COX-2 is a known mediator of tumour growth, we explored the potential benefit of COX-2 inhibition in combination with VEGFR inhibition in attempts at delaying tumour progression on Su. Cx43 expression was measured with reverse-transcription polymerase chain reaction (RT-PCR) and quantitative (Q)-PCR. To retrospectively compare sensitivity and specificity of admission nonenhanced computed tomographic (CT) scans with those of CT angiographic source images in detection of early ischemic changes in middle cerebral artery (MCA) stroke and to retrospectively compare admission nonenhanced CT scans with CT angiographic source images in delineation of final infarct extent, with follow-up images as reference. To evaluate visual outcomes in combination therapy with photodynamic therapy (PDT) and intravitreal triamcinolone acetonide (IVTA) for subfoveal choroidal neovascularization (CNV) from age-related macular degeneration (AMD). To characterize the naturally occurring expanded-spectrum beta-lactamase from an Escherichia coli clinical isolate and to compare it with a wild-type beta-lactamase. GABAARs that contain the beta3 and delta subunits were shown to be enhanced by alcohol concentrations that mirror the concentration dependence of alcohol responses in humans. On the other hand, the co-administration of morphine with naloxone, an opioid receptor antagonist, attenuated the inhibitory effect of morphine.

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