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Imitrex (Sumatriptan)

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Imitrex belongs to a class of drugs known as triptans. It affects a certain natural substance (serotonin) that causes narrowing of blood vessels in the brain. Imitrex may also relieve pain by affecting certain nerves in the brain.

Other names for this medication:
Migratan, Sumatriptan, Suminat, Sumitrex

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Also known as: Sumatriptan


Imitrex is a perfect remedy in struggle against the symptoms of migraine headaches. Imitrex acts by narrowing blood vessels in the head and stopping pain signals from being sent to the brain. It is selective serotonin receptor agonists. Imitrex is also known as Sumatriptan, Imigran. Generic name of Imitrex is Sumatriptan. Brand names of Imitrex are Imitrex, Imitrex nasal.


Use sumatriptan as soon as you notice headache symptoms. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Never use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks.

Sumatriptan is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.

This medicine comes in a vial (bottle), a needle-free injector device, or a prefilled cartridge for an auto-injector syringe. Each type is for one use only.

Read and carefully follow any Instructions for Use provided with your medicine. Do not use sumatriptan if you don't understand all instructions for proper use. Ask your doctor or pharmacist if you have questions.

Prepare your injection only when you are ready to give it. Do not use a vial if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.

After an injection: If your headache does not completely go away, call your doctor before using a second injection. If your headache goes away and then comes back, use a second injection if it has been at least 1 hour since your first injection. Do not use more than 2 injections in 24 hours. Call your doctor if your symptoms do not improve.

Store at room temperature away from moisture, heat, and light. Throw away any unused medicine after the expiration date on the label has passed.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

Detailed Imitrex dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include tremors, skin redness in your arms or legs, weakness, loss of coordination, breathing problems, blue-colored lips or fingernails, vision problems, or a seizure (convulsions).


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Throw away used syringes or autoinjectors in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Detailed Imitrex dosage information

Side effects

The most common side effects associated with Imitrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Imitrex Statdose within 24 hours before or after using another migraine headache medicine, including:

Imitrex Statdose tablets or nasal spray, almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, zolmitriptan; or ergot medicine such as dihydroergotamine, ergotamine, ergonovine, or methylergonovine.

Avoid driving or hazardous activity until you know how Imitrex Statdose will affect you. Your reactions could be impaired.

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Miniplate fixation for avulsion injuries of the flexor digitorum profundus insertion. We have developed an immunofluorescence flow cytometric method for the simultaneous detection of different GST-isoenzymes and of DNA in fixed cells. Uterine fibroids: clinical manifestations and contemporary management. Copper-catalyzed bis-arylations of alkenes leading to oxindole derivatives. Gamma glutamyl transpeptidase (GGT) and alpha-fetoprotein (AFP) in the amnionic fluids were measured for reference, a antenatal diagnosis of the fetal congenital toxoplasmosis infection could thus be made. Structure of a tRNA-dependent kinase essential for selenocysteine decoding. A formula for predicting optimal dosage of nedaplatin based on renal function in adult cancer patients. In this work, we systematically investigate the unidirectional scattering in the system of plasmonic nanoparticles. The purpose of this study was to evaluate potential moderators of the relationship between alcohol dependence and suicide and medically serious suicide attempts by using case-control data gathered in the Canterbury region of New Zealand for the Canterbury Suicide Project.

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This article is the review of literature about molecular pathogenetic and prognostic factors of pancreatic cancer. The antigenic variants did not induce cross-protection among themselves, but induced only variant-specific immunity in vivo. In a prospective study from 1993 to date, EDMR-No GA was considered as first-line postnatal management in 35 children. Retinoic acid induces discrete Wnt-signaling-dependent differentiation in F9 cells. In a randomized cross-over study healthy non-obese male human subjects received standardized isocaloric, isovolumetric meals consisting of either carbohydrate, protein or fat and a non-caloric control meal consisting of an equal volume of water. A series of nonadiabatic rate constant expressions for both homogeneous and electrochemical PCET reactions have been derived in various well-defined limits. Traditional laparoscopic surgery with carbon dioxide insufflation precluded patients with underlying cardiovascular or pulmonary disease from minimal invasive surgery. Neonatal Patent Ductus Arteriosus Ligation Operations Performed by Adult Cardiac Surgeons.

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A great deal of research has focused on deciphering the TRAIL receptor signaling cascade and intracellular regulation of this pathway, as many human tumor cells possess mechanisms of resistance to TRAIL-induced apoptosis. The influence of different experimental conditions of the USP paddle method on the release profile was investigated. 25 cases of patients with osteoarthritis (OA) and non-synovitis (Non-S) were regarded as the negative control. There is scope for reports designed to maximise existing NHS resources and to assess the role of prevention, care integration and other ways to cut long-term costs. The period of organ ischaemia outside the body is subject to a number of biochemical stress factors which become known in more detail as knowledge on biochemical and immunological mechanisms improves. Here we show that the restriction endonuclease EcoRV slides along the DNA, scanning approximately 1000 bp in one binding event. A general property of these systems is applied to the problem of signal specificity: slight differences in the input may result in completely different outputs, which negates the necessity of specific proteins to each pathway. pylori and PAD in individuals with a normal or high homocysteine level was investigated.

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Heat-related illnesses, deaths, and risk factors--Cincinnati and Dayton, Ohio, 1999, and United States, 1979-1997. In the future, we must determine the frequency of coalitionary takeovers in this population and assess its ultimate consequences for male-male social relationships. The results obtained by the authors were based on the examination of 453 patients. A Case of Congenital Infection: Missed Opportunities for Prevention and the Importance of Maternal Testing and Screening. A 56 year old man was admitted cause he had increasing symptoms as weakness, lethargy, disorientation. To describe the baseline characteristics and treatment of the patients randomized in the PARADIGM-HF (Prospective comparison of ARNi with ACEi to Determine Impact on Global Mortality and morbidity in Heart Failure) trial, testing the hypothesis that the strategy of simultaneously blocking the renin-angiotensin-aldosterone system and augmenting natriuretic peptides with LCZ696 200 mg b.i.d. A comparison between a conventional optical method and image-analysis for measuring the unimpeded eruption rate of the rat mandibular incisor. Lymphocytic gastritis (LG), characterized by marked intra-epithelial lymphocytosis in the gastric mucosa, has been frequently associated with both celiac disease (CD) and H.

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The detection and characterization of highly enriched uranium (HEU) presents a large challenge in the non-proliferation field. Relation between age and head and neck cancer recurrence after surgery: a multivariate analysis. Initial attempts at closure of the seven-membered D ring were unsuccessful. RXR alpha selectivity is reduced on replacement of the 4-carboxylphenyl group by a 2-carboxyl-5-thienyl group or the 9-cis-retinoic acid methylpentadienoic acid terminus. At 30 min after intravenous injection of pyrilamine, the tissue-to-plasma concentration ratio (K(p)) in the heart and pancreas was higher, whereas the K(p) in kidney and testis was lower in jvs mice compared with wild-type mice.

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Comparison of archaeal and bacterial community structures in heavily oil-contaminated and pristine soils. Experimental studies on the acute effect of insulin on the liver. These SAA1-linked microbial and transcriptome interactions were further reproduced with data from the pediatric IBD RISK cohort. The results showed that, in general, ERK1/2 inhibition favored osteoblast and adipocyte differentiation of MSCs grown on Ti-Machined. Equal enhancement of the incidence of hepatocellular carcinomas was obtained with 250, 500 and 1000 ppm sodium phenobarbital. To establish the roles of lipopolysaccharide (LPS)/CD14/toll-like receptor 4 (TLR4)-mediated inflammation in a rat model of human necrotizing enterocolitis (NEC). elegans Hox proteins in the control of three different cell-fate decisions: the regulation of cell migration, the specification of serotonergic neurons, and the specification of a sensory structure. Heparin and heparinoids prevent the binding of immune complexes containing nucleosomal antigens to the GBM and delay nephritis in MRL/lpr mice. Two patients with postoperative problems associated prilosec breastfeeding with the patellar implant are described.

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A study group was formed in 1989 by the Oral Health Program of WHO, Geneva, to consider the possibility of reducing dental caries by adding fluoride to sugar. No resistant plant contained an Ile-1,781-Leu substitution, previously shown to confer resistance to APPs and cyclohexanediones (CHDs). The rate constants determined by this model for movement of sterols between cytoplasm and plasma membrane were similar for both cholesterol and 25OHC, whereas those for esterification and ester hydrolysis as well as those for bidirectional movement between plasma membrane and extracellular medium were greater for 25OHC than for cholesterol. Traditionally, surgery was used only as a last resort after patients failed prolonged medical and/or endoscopic therapy. Comparison of work incapacity in a Soviet region with analogous East German values. The stomal implant is often the only site of metastatic disease at presentation. The analysis presented here lead to interesting and complementary conclusions about the response across time of human epidermal keratinocytes after exposure to nanomaterials. Application of caffeine reveals input frequency-dependent determination of signal-traveling routes between primary and secondary visual cortices in rats. The graying of HIV/AIDS: preparedness and needs of the aging network in a changing epidemic. The calculated probabilities show no sequence dependence at premelting temperatures, in agreement with proton exchange measurements.

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Improving of methods of production and screening of monoclonal antibodies to Salmonella antigens. beta1 integrins were required for adhesion and proliferation on Matrigel, as shown by immunological blockade experiments. Glucosylceramide Synthase Is Involved precio del glucophage xr 750 mg in Development of Invariant Natural Killer T Cells. Isolated bladder metastasis causing large bowel obstruction: a case report of an atypical presentation of intussusception. These symptoms disappeared completely after 4 weeks of treatment with creatine after which the patient regained all his previous mental abilites.

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The diagnosis was based on clinical events, x-ray films and mainly on the optimal answer to antibiotic treatment. Self-construal differences in neural responses to negative social cues. A new neuroectodermal syndrome (designated CHIME syndrome) was described in 1983 with a total of four patients reported, it is presumed to be an autosomal recessive disorder because of recurrence in sibs. Determination of norvasc drug class class drug class toxins involved in ciguatera fish poisoning in the Pacific by LC/MS. Fixed interval/fixed ratio performance in adult monkeys exposed in utero to methylmercury. Prevalence and predictors of inappropriate anticoagulation in patients with a CHA2DS2-VASc score of 0 and atrial fibrillation. One of the best methods for fabricating a bio-functional tissue engineering scaffold is to load bioactive agent into the scaffold.

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Evidence is provided that two distinct phorboid chemotypes of croton oil exist, differing in the relative proportion of type-A and type-B esters and showing different stability to deacylation. The occurrence of Echinococcus granulosus in coyotes (Canis latrans) in the central valley of California. Endogenous endothelin maintains coronary artery tone by endothelin type A receptor stimulation in patients undergoing coronary arteriography. Accumulation of PH-PAs with the time of starvation was especially significant for PUT and CAD. Evaluation of 6- and 12-month supervised exercise training on strength and endurance parameters in patients with peripheral arterial disease. Arrest in hospital: a study of in hospital cardiac arrest outcomes. Forward trace conditioning consisted of 10 trials in which a 16-s tone conditional stimulus (CS) was followed by a 28-s stimulus-free trace interval and then a mild footshock unconditional stimulus (US).

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Competitive binding of calcium and magnesium to streptococcal lipoteichoic acid. Patients with underlying cardiac disease are at a particularly increased risk for worse outcomes following cancer therapy. The variation found in birth weight over the past 10-year period was explained by changes in maternal prepregnancy weight, height, smoking habits, educational level, and caffeine intake over the same period. (1) To determine whether high-frequency sensorineural hearing loss (HF SNHL) is accompanied by deterioration in temporal resolution in the low-frequency region where hearing sensitivity is within normal range. We performed immediate reconstruction in eight patients after ablative surgery, and late reconstruction due to radiation-induced complications in three. Following discussion of the anatomical substrates, a clinical correlation is then provided to confirm and reinforce these experimental observations.

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Erectile dysfunction affects up to 30 percent of men between 40 and 70 years of age. Does increased PGF2 alpha receptor concentration mediate PGF2 alpha-induced luteolysis during early diestrus in the pig?. A multidisciplinary team is required to carry out a suitable treatment, composed of paediatricians, dieticians, nurses, psychologists and psychiatrists. While it has been demonstrated that this tyrosine kinase activity is necessary for the action of a number of transmembrane tyrosine kinase receptors, no evidence of this type has been adduced to date with respect to the signaling requirement of the IGF-I receptor. Oxidative stress in elderly chronic renal failure patients: effects of renal replacement therapies on cell membrane fluidity. To verify the mechanism of the hepatitis B viral clearance using clinical data. These results confirm that mites have the capability to discriminate their kin and, moreover, that they are able to accurately perceive differences between close relatives from sib-mating lines. Pathologists, however, have long noted that calcification may occur early in atherosclerosis and, at times, may appear histologically identical to organized bone, including areas resembling bone marrow.

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The reduced form is more stable than the oxidized form, suggesting that the strong oxidizing force of DsbA comes from the tense conformation of the oxidized form. Position statement: integrating genetics competencies into baccalaureate and advanced nursing education. School environment and behaviour of role models play a crucial part in student smoking. 14-3-3 proteins interact with many proteins involved in cellular signaling, including the glucocorticoid receptor (GR). Acute phase proteins and interleukin-6 serum levels in patients with chronic arterial occlusion. It has been demonstrated that sentinel lymph node biopsy and axillary dissection can be performed adequately in SSM. Because it is easy to evaluate the operating characteristics of this procedure for a given sample size and specified number of covariates, our method facilitates the selection of hyperparameter values through prior-predictive simulation.

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Increased numbers of multilocular functionally active brown adipocytes, and improved thermoregulation was also observed in obese animals lacking TNF-alpha function. When the global letter and the target were frequently congruently oriented, the response times increased with growing orientation disparity between them. Functional Kv 1-4 channels were stably expressed in filter-grown MDCK cells which form a polarized epithelium with two distinct plasma membrane domains: a basolateral and an apical cell surface. Again, bacteriological differences imply that diabetic infections might be populated by different bacterial flora. Teicoplanin treatment of infected rabbits reduced bacterial numbers in the blood and in the vegetations. Data are presented on induced abortions in the Federal Republic of Germany in 1984, together with some comparative statistics for earlier years. Adding complex clinical assessment of cardio-vascular functional capacity to diagnostic workup program for individuals having long-term effects of acute sarin and soman poisonings enables simultaneous characteristic of various hemodynamic changes and their relationships, early diagnosis of hemodynamic disorders, opportune diagnosis of clinical cardiovascular syndromes. Cognitive idiosyncrasies among children with the chronic fatigue syndrome: anomalies in self-reported activity levels. Effect of selective blockade of endothelin ETB receptors on the liver dysfunction and injury caused by endotoxaemia in the rat. Chondrocytes were isolated separately from the equine patella groove and the femoral condyle, representing high loaded areas (HLA) and low loaded areas (LLA), respectively, of 6 specimens of different ages.

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