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Nipin (Nifedipine)

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Nipin belongs to the group of Calcium Channel Broker (CCB). This medication is used to control chest pain (angina) and hyper tension (high blood pressure). Nipin was produced by Bayer, a reputed German pharmaceutical company. The initial studies on the drug were undertaken in the year of 1970. This drug is approved by FDA.

Other names for this medication:
Adalate, Atanaal, Atenerate, Belnif, Calcianta, Citilat, Cordaflex, Corinfar, Depin, Duranifin, Glopir, Macorel, Marivolon, Menoprizin, Myogard, Nelapine, Nidicard, Nidipine, Nifangin, Nifecap, Nifecard, Nifed, Nifedicor, Nifedipine, Nifedipinum, Nifensar, Nifestad, Nifin, Nilol, Nipidin, Noviken, Nycopin, Nyefax, Oxcord, Pabalat, Sepamit

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Nipin OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Nipin and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Nipin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Cardiac damage after carotid intervention: a meta-analysis after a decade of randomized trials. Academic nursing education guidelines: tool for bridging the gap between theory, research and practice. To examine trends in glucose tolerance and coronary risk among Aboriginal people from a group of homeland communities in central Australia during a 7-year follow-up period. Incomplete consumption data overstate the importance of fructose in contemporary disease. The aim of this study was to determine the spectrum of antimicrobial activity of 11 samples of stingless bee honey compared to medicinal, table and artificial honeys. Researchers have consistently found that people with schizophrenia score more poorly than others on a wide array of cognitive tasks and that these deficits persist even when the illness is in remission. Double strand break rejoining after irradiation of human fibroblasts with X rays or alpha particles: PFGE studies and numerical models. Stereotactic radiosurgery and the risk of haemorrhage from cavernous malformations. We have studied the expression of plasminogen activator inhibitor 2 (PAI-2) in the adult mouse and during embryonic development using immunohistochemistry and the polymerase-chain reaction.

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Recurrent respiratory papillomatosis in children: a retrospective study of management and complications. Hence, the changes in local excitatory connectivity did not occur in all circuits involving pyramidal neurons. Treatment of orogastrointestinal candidosis in SCID mice with fluconazole alone or in combination with recombinant granulocyte colony-stimulating factor or interferon-gamma. Improvement following correction of secondary mitral regurgitation in end-stage cardiomyopathy with mitral annuloplasty. Neuraminidase inhibitors for influenza A and B: PROSE may be as useful as POEMs. In the present study, based on our experience with false median cleft lip, we set forth a hypothesis that 2 upper labial frenums can be found in true median cleft lip, whereas no upper labial frenum is found in false median cleft lip. In this paper, 3D-descriptors that separate random conformations from active conformations of small molecules are sought. A 35-year-old man with hematuria had a polypoid bladder lesion, which on microscopic examination was a fibroepithelial polyp containing numerous stromal cells with atypical, hyperchromatic nuclei.

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Eight studies attempted to determine if there was a temporal association between developing ASD and receiving the MMR vaccine. Bivalved palatal transposition flaps for the correction of acquired nasopharyngeal stenosis. This group of disorders is generally considered to be a pediatric muscular dystrophy when in actual fact, this case report may represent a spectrum of subclinically affected adults. Localization and turnover studies of membrane nicotinamide adenine dinucleotide glycohydrolase in rat liver. Correction: Nonlinear Dynamics Forecasting of Obstructive Sleep Apnea Onsets. Neuropathic symptoms improved in conjunction with normalization of serum-free light chains.

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The electromyographic bridge (EMGB) detects surface electromyographic signals from a non-paretic limb. Clinical and experimental investigations have reported that manufactured surface topographies have significant effects on cell adhesion and tissue integration. Leishmanial protein kinase C modulates host cell infection via secreted acid phosphatase. This article aims to help practitioners perform an optimal ultrasonographic examination. No significant differences in duration of GH treatment and testicular volume at the start of treatment or at final height were found between the boys with ISS and those with IGHD. This article reviews the structure of pRNA to demonstrate that its structure plays a vital role in its function, and focuses on methods and unique approaches that lead to the elucidation of pRNA structure. The efficacy of therapy was assessed by evaluating clinical symptoms, laboratory data, and cholangiograms. While a variety of cellular functions have been ascribed to sphingolipids, in many cases proof of the concept has yet to be well established.

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Fulminant metastatic calcinosis with cutaneous necrosis in a child with end-stage renal disease and tertiary hyperparathyroidism. Most catheter-based visualization techniques will provide insight into components of the local atherosclerotic plaque which may limit their predictive value for the occurrence of a clinical event. Primary care physicians can play a unique role in recognizing and treating patients with alcohol problems. Roentgenologic determination of the charge of batteries in implanted heart pacemakers. The present study demonstrated that human recombinant IL-2 (hr-IL-2) and mouse recombinant IL-2 (mr-IL-2) not only did not antagonize audiogenic seizures in DBA/2 mice but increased the incidence of seizures after the highest doses studied. One of the specific monoclonal antibodies was shown to be directed against the major capsid protein while the other specific monoclonal antibody and the broadly reacting one reacted with the low molecular weight viral polypeptides.

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Endometrial resection follow up: late onset of pain and the effect of depot medroxyprogesterone acetate. We reviewed the literature to determine the effects of statins on symptoms, exercise performance and activity levels in physically active individuals. Primers for human endogenous retrovirus-3 (HERV-3), an internal control, were adopted. GC and CS were also characterized in terms of total polyphenols and antioxidant capacity. Two replication parameters, synthesis of individual replicons and adjacent replicon clusters, were measured using DNA fiber autoradiography in a radiosensitive form of group C xeroderma pigmentosum (XP) XP2SP, in group C XP4SP, in group A Cockayne syndrome (CS) CS1SP and two normal human fibroblast strains.

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Their acyl-CoA products regulate metabolic enzymes and signaling pathways, become oxidized to provide cellular energy, and are incorporated into acylated proteins and complex lipids such as triacylglycerol, phospholipids, and cholesterol esters. Other genes are not expressed when cdk-9, spt-4, and spt-5 are inhibited simultaneously, suggesting that these genes require P-TEFb in an additional mechanism, and that they and heat shock genes are regulated through different P-TEFb-dependent elongation pathways. It may be the first report on transformation of detoxify gene of pesticide resistant culex into Synechococcus strain. These are signs of the retrograde ultrastructural and biochemical alterations, which could participate in the pathophysiological mechanism underlying the trigeminal neuralgia. Identification of a wide biomarker repertoire with high specificity and reliability of detection appears to be a solution to this problem. To our knowledge, this is the first report of successful SCT in the management of CDA type I. To estimate calorie-income elasticity and to determine calorie and protein intake levels of Addis Ababa population.

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We present a 6-month-old girl with the unusual combination of microphthalmos, facial capillary hemangioma and Dandy-Walker malformation. The gradient gives rise to an inhomogeneous water swelling, and presumably to a liquid crystal-to-gel transition in the lamellar region closest to humid air. Management of severe burn injury (SBI) requires prompt, complex, and aggressive care. For example, allowing that peptides may enter neurons by a variety of mechanisms and then be christened neuroendocrine peptides, it has become a compelling issue to know which cells are manufacturing the peptide. Flexible stereoselective functionalizations of ketones through umpolung with hypervalent iodine reagents. The measurements were performed as follows: (1) errors at photography: 1) errors by the individual photographer 2) errors among three photographers. Decreased hip adduction after instruction was comprised of motion at both the pelvis and femur.

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The objective of the present study was to evaluate different methods (mechanical fragmentation, gradients, flow cytometry) to separate and purify T. Treatment consisted in the application of an amount of the solution sufficient to obtain a whitening/yellowish reaction. The CPC-1 initially self-assembles into nanoparticles with pegylated coronas. Here, we focus on how the use of a specific ITS2 fungal barcoding primer pair biased for AMF changes the interpretation of AMF community patterns from three mountain vineyards compared to a novel AMF-specific approach on the 18S. Histopathological liver changes resembling primary biliary cirrhosis were induced in an experimental animal model. Vertical Ramus Osteotomy (VRO) provided access of the internal carotid artery (ICA) up to the base of the skull, with low incidence of cranial nerve injury temporo-mandibular joint (TMJ) pain and no preincision preparation. In this study, genetic polymorphism of two tRNA-liked short tandem repeat (STR)-containing loci, R-R and S-Q, was analyzed in order to clarify further the genotypic differences among E. These preliminary data suggest that continuous verapamil infusions can safely and effectively control ventricular rate in patients with rapid atrial tachyarrhythmias, until oral medications can be lanoxin mg started. Gravity is a constant factor feeding plants with reliable information for the spatial orientation of their organs.

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This study aimed to elucidate the antihypertensive effect, pharmacokinetics and safety of candesartan cilexetil in patients with ERF undergoing haemodialysis. The most frequent symptoms and signs were: fever, headache and arthralgia. The monitoring of frying oils by an effective and rapid method is one of the demands of food companies and small food retailers. Growth-restricted children had significantly poorer performance than non-growth-restricted children on a wide range of cognitive tests, supporting the conclusion that growth restriction has long-term functional consequences. The improvement rate, cure rate, precision and accuracy of the puncture, incidence of bleeding, puncture infection rate, average length of stay, clinical efficacy, and long-term follow-up were evaluated.

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Sensitive detection methods should facilitate the design of improved food processing methods to ensure virus-free food. Conversely, sodium orthovanadate, a potent inhibitor of tyrosine phosphatases can reproduce the two effects of aFGF, indicating that protein tyrosine phosphorylations are determinant in the two pathways. To date, such decoding paradigms were mostly used for visual modalities. Polar auxin transport, which is required for the formation of auxin gradients and directional auxin flows that are critical for plant pattern formation, morphogenesis, and directional growth response to vectorial cues, is mediated by polarized sub-cellular distribution of PIN-FORMED Proteins (PINs, auxin efflux carriers), AUX1/AUX1-like proteins (auxin influx facilitators), and multidrug resistance P-glycoproteins (MDR/PGP). The parameters of healing (amounts of protein and collagen deposited at the site of the wound) were significantly lower in animals with burn injuries on days 7 and 14. The presence of amylase suggests that these predators are more committed to plant feeding than other species of predators that lack this enzyme.

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Fission yeast myosin Myo2 is down-regulated in actin affinity by light chain phosphorylation. We performed a retrospective cohort review of our requests for ultrasound-guided PIV access in the intensive care unit between September 2007 and February 2008. We study theoretically nonequilibrium noise in the fractional quantum Hall regime for an Aharonov-Bohm ring with a third contact in the middle of the ring. The current investigation compared patients treated on and off trial with the same standard arm treatment regimen. Impact of the implantable cardioverter-defibrillator on rehospitalizations. We have modified the intron by chemical and enzymatic treatment in the presence and absence of the protein to determine the impact of the protein on the secondary and tertiary structures of the intron. We investigated whether post-exercise first minute abnormal heart rate recovery (HRR1) helps to predict the presence and severity of CAD, because of some confounding data. Giant Rashba splitting in 2D organic-inorganic halide perovskites measured by transient spectroscopies. We have previously reported that administration of a cAMP taking claritin d while breastfeeding -permeable analog (CPT-cAMP) along with a phosphodiesterase inhibitor (IBMX) improves long-term habituation (LTH).

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