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Prograf (Tacrolimus)

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Prograf is an immunosuppressant that lowers the activity of your immune system. You need a suppressed (lowered) immune system after receiving an organ transplant so your body doesn't reject the new organ.

Other names for this medication:
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Also known as: Tacrolimus


Prograf (tacrolimus) weakens your body's immune system, to help keep it from "rejecting" a transplanted organ such as a kidney. Organ rejection happens when the immune system treats the new organ as an invader and attacks it.

Prograf is a prescription medicine and is used together with other medicines to prevent your body from rejecting a heart, liver, lung, or kidney transplant.

Prograf is supplied as oral capsules, granules for oral suspension, and as an injection for intravenous use.

Prograf capsules and oral granules are immediate-release medicines and they are not the same as tacrolimus extended-release tablets or tacrolimus extended-release capsules. Your healthcare provider should decide what medicine is right for you.


Generic Prograf can be taken in form of capsules (0.5 mg, 1 mg, 5 mg) and in injectable form. The dosage of Generic Prograf depends on the type of your disease and health state. Take Generic Prograf 2 times a day. Take Generic Prograf orally, once a day with or without food. Avoid grapefruit or grapefruit juice. Avoid vaccinations. Do not stop taking Generic Prograf suddenly.


If you overdose Generic Prograf and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Prograf are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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