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Sarteg

Sarteg is indicated for the treatment of hypertension to reduce the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. It is also indicated for the treatment of heart failure (NYHA class II-IV) and for left ventricular dysfunction or failure after myocardial infarction when the use of an angiotensin-converting enzyme inhibitor (ACEI) is not appropriate.

Other names for this medication:
Alpertan, Alsart, Alsartan, Arovan, Cardival, Codiovan, Combisartan, Cordinate, Cotareg, Diovane, Disys, Dosara, Kalpress, Miten, Nisisco, Provas, Rixil, Sarteg, Starval, Tareg, Teval, Valaplex, Valcap, Valitazin, Valpresan, Valpress, Valsacor, Valsan, Valsaprex, Valsar, Valsartan, Valsartanum, Valzaar, Valzide, Varexan, Vartalan, Vasaten

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Also known as: Valsartan

Description

Sarteg (valsartan) is an angiotensin II receptor blocker (sometimes called an ARB). Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Sarteg is used to treat high blood pressure (hypertension) in adults and children who are at least 1 year old. Lowering blood pressure may lower your risk of a stroke or heart attack.

Sarteg is also used in adults to treat heart failure and lower your risk of needing to be hospitalized, and to lower your risk of death after a heart attack.

Dosage

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 40 mg orally twice a day Maintenance dose: 80 to 160 mg twice a day. The dose should be increased to the highest dose tolerated by the patient.

Usual Adult Dose for Hypertension:

Initial dose: 80 to 160 mg orally once a day. Maintenance dose: 80 to 320 mg orally once a day

Usual Adult Dose for Myocardial Infarction:

Initial dose: 20 mg orally twice a day Maintenance dose: The initial dosage may be titrated upward within 7 days to 40 mg twice daily, with subsequent titrations to a target maintenance dose of 160 mg twice a day as tolerated by the patient. If symptomatic hypotension or renal dysfunction occurs, consideration should be given to a dosage reduction. Comment: Valsartan may be initiated as early as 12 hours after a myocardial infarction, and may be given with other standard postmyocardial infarction treatment, including thrombolytics, aspirin, beta blockers, and statins.

Usual Pediatric Dose for Hypertension:

6 to 16 years: Initial dose: 1.3 mg/kg once a day (up to 40 mg) Maintenance dose: up to 2.7 mg/kg (up to 160 mg) once a day titrated according to patient response Comments: If the calculated dosage does not correspond to the available tablet strengths, or if children are unable to swallow tablets, the use of a suspension (which can be prepared from the tablets) is recommended. The valsartan dose may need to be increased if the suspension is replaced by a tablet. No data are available in pediatric patients either undergoing dialysis or with a glomerular filtration rate less than 30 mL/min.

Detailed Sarteg dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep your medicine container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Sarteg are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Sarteg if you are allergic to valsartan.

To make sure Sarteg is safe for you, tell your doctor if you have:

a heart condition other than one being treated with Sarteg; kidney disease (or if you are on dialysis); or if you are on a low-salt diet.

Do not use Sarteg if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Valsartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

If you plan to get pregnant, ask your doctor for a safer medicine to use before and during pregnancy. Having high blood pressure during pregnancy may cause complications in the mother and the baby.

You should not breastfeed while using this medicine.

Sarteg is not approved for use by anyone younger than 1 year old.

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To understand the biochemical mechanism of p100 processing, we searched for cellular factors interacting with the C-terminal regulatory region of p100 using the yeast two-hybrid system. The early part of the P300 component, possibly P3a, may be related to the mechanisms that generate SSNA. Hygienic behavior, in which individual honeybees detect chemical stimuli from diseased larvae and subsequently remove the diseased brood from the nest, is one type of social immunity that reduces pathogen transmission. X-ray absorption near-edge structure (XANES) spectroscopy and spectromicroscopy have been extensively used to characterize biominerals. Under combustion gas atmosphere, the solid yield for torrefaction of EFB became smaller as the temperature increased. Experimental study of the effect of a new antioxidant agent on learning and memory. The main dependent variable was the latency of the recognition decision. This revealed enhanced susceptibility to fungal penetration of young RBOHF2-silenced leaf tissue but strongly reduced susceptibility of older leaves when compared with controls. Perioperative and long-term outcomes of laparoscopic, open abdominal, and vaginal surgery for endometrial cancer in patients aged 80 years or older. Rigid and flexible docking techniques were used for analysis of binding mode and design of new inhibitors.

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The growth of electrodeposited lithium microstructures on metallic lithium electrodes has prevented their use in rechargeable lithium batteries due to early performance degradation and safety implications. The impact of the implementation of physician assistants in inpatient care: A multicenter matched-controlled study. The effects of the current strategies for disinfection of drinking water systems in large buildings (chlorination, copper and silver ionization, and hyper-heating) were compared with a new generation of bismuth thiol (BT) biocides. When the liver was perfused with RBC-free buffer, H2O2 production and consequent injury progressing to apoptosis were initiated in the sinusoidal endothelial cells (SECs). A defect in insulin secretion seems to dominate in lean elderly male Swedish subjects with NIDDM. These mice gained weight and showed markedly improved macro- and microscopic parameters of colitis.

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