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Soflene (Adapalene)

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Soflene is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Soflene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Chloromycetin, Asacol, Effexor, Leukeran, Casodex, Phenergan, Moduretic, Tofranil, Neoral, Zovirax, Almet, Ession, Sulfatrim, Perclin, Azoprine, Nusar,

Also known as: Adapalene


Soflene is a third-generation topical retinoid primarily used in the treatment of acne. Soflene is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Soflene gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Soflene works under the skin surface to unclog pores and clear up pimples. Soflene is also known as Adapalene, Adapen, Adaferin. Generic name of Soflene is Adapalene.


It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin.

Do not apply this medicine to windburned or sunburned skin or on open wounds.

Do not use this medicine in or around the eyes, lips, or inside of the nose. Spread the medicine away from these areas when applying. If the medicine accidently gets on these areas, wash with water at once.

Apply the medicine to clean, dry areas of the skin affected by acne. Rub in gently and well. Wash your hands afterwards to remove any medicine that may remain on them.

To help clear up your acne completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a short time. If you stop using this medicine too soon, your acne may return or get worse.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (gel): For acne: Adults and teenagers—Apply a small amount as a thin film once a day, at least one hour before bedtime. Apply the medicine to dry, clean areas affected by acne. Rub in gently and well. Children—Use and dose must be determined by your doctor.


If you overdose Soflene and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Soflene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies of this medicine have been done only in adult patients, and there is no specific information comparing use of adapalene in children up to 12 years of age with use in other age groups. In teenagers, adapalene is not expected to cause different side effects or problems than it does in adults.

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