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Terramycin (Oxytetracycline)
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Terramycin

Terramycin is a broad-spectrum antibiotic used to treat a wide variety of infections caused by certain bacteria. Terramycin is a tetracycline antibiotic. Terramycin's primary use is for the treatment of acne vulgaris and rosacea. It is also used to treat certain bacterial infections of the lung, skin, genitals and bladder, certain types of infectious diarrhoea and sexually-transmitted diseases (STD).

Other names for this medication:
Betacycline, Cotet, Dynoxytet, Ecomycin, Geomicina, Innolyre, Oxyteracin, Oxytetracycline, Tetracin

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Also known as: Oxytetracycline

Description

Terramycin is a product of the metabolism of Streptomyces rimosus and is one of the family of Terramycin antibiotics. A 1 percent solution in water is acidic (pH about 2.5). Its potency is affected in solutions more acid than pH 2 and it is rapidly destroyed by alkali hydroxides.

Terramycin diffuses readily through the placenta into the fetal circulation, into the pleural fluid and, under some circumstances, into the cerebrospinal fluid. It appears to be concentrated in the hepatic system and excreted in the bile, so that it appears in the feces, as well as in the urine, in a biologically active form.

Inert ingredients in the formulation are: glucosamine hydrochloride; hard gelatin capsules (which may contain Red 3, Yellow 10 and other inert ingredients); magnesium stearate; sodium lauryl sulfate; starch.

Dosage

Take Terramycin by mouth with a full glass of water on an empty stomach at least 1 hour before or 2 hours after eating. Do not lie down for 30 minutes after taking Terramycin. Avoid taking milk, dairy products, calcium-enriched juices before and after consuming the drug. It is better to take Terramycin every day at the same time. Terramycin treats different types of bacterial infections and can be used both by adults and by children. Thus, each age has different instructions. For children above 8 years of age: the usual daily dose is 25–50 mg per kg of body weight divided into 4 equal doses. For Adults: the usual daily dose is 1–2 g divided in 4 equal doses, depending on the severity of the infection. For treatment of brucellosis, 500 mg oxytetracycline four times daily for 3 weeks should be accompanied by streptomycin, 1 gram intramuscularly twice daily the first week, and once daily the second week. For treatment of uncomplicated gonorrhea, when penicillin is contraindicated, tetracycline may be used for the treatment of both males and females in the following divided dosage schedule: 1.5 grams initially followed by 0.5 gram q.i.d. for a total of 9.0 grams. For treatment of syphilis, a total of 30–40 grams in equally divided doses over a period of 10–15 days should be given. Do not stop taking Terramycin suddenly. Therapy should be continued for at least 24–48 hours after symptoms and fever have subsided.

Overdose

If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately. Symptoms of Terramycin overdose: retching, diarrhoea, nausea.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Terramycin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Terramycin if you are allergic to Terramycin components. Do not use Terramycin if you take antacids containing aluminum, calcium, or magnesium impair absorption. Do not use Terramycin if you have liver problems, kidney disease. Do not take Terramycin if you're pregnant or you plan to have a baby, or you are breastfeeding. Terramycin is not to use in children under 8 years old. Do not take Terramycin if you suffer from porphyria. Use of Terramycin in children may cause permanent discoloring of the teeth. Do not drive, operate machinery or perform other possibly unsafe tasks until you know how you react to Terramycin. Try to be careful with sunbeams. Terramycin makes skin sensitive to sunlight. Protect skin from the sun. It's not recommended to use hormonal birth control as it may not work. To prevent pregnancy, use an extra form of birth control.

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