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Yasmin (Drospirenone)
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Yasmin

Yasmin is a combined oral contraceptive pill. It works by preventing the release of egg (ovulation) and affecting sperm movement in the womb to prevent its union with the egg. It also changes the lining of the womb and renders it unsuitable for pregnancy.

Other names for this medication:
Drospirenone, Rasmin

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Also known as: Drospirenone

Description

Yasmin is a hormonal birth-control medication produced by Bayer Schering Pharma. Yasmin combines two synthetic analogs for natural female sex hormones - Ethinyl Estradiol and Drospirenone. Ethinyl Estradiol is a synthetic estrogen while Drospirenone is a fourth generation progestin (synthetic progestogen). - Contraception: Ethinyl Estradiol and Drospirenone block the secretion of gonadotropins (follicle stimulating hormone, FSH and luteinizing hormone, LH) thereby provide a strong contraception. Ethinyl Estradiol stops ovaries from releasing an egg and Drospirenone affects the cervical mucus and alter the lining of the uterus making it more difficult for sperm fertilize the egg. Yasmin is also used for the treatment of such health conditions: Premenstrual dysphoric disorder: Drospirenone is a fourth generation progestin with beneficial effects in reducing hyperandrogenic states and fluid retention. In addition to being closer to natural progestin, Drospirenone possesses potent anti-mineralocorticoid properties, meaning it has an ability to prevent fluid retention and accumulation in the soft tissues of the body particularly the breast and pelvic regions whereby symptoms of premenstrual dysphoric disorder (PMDD), like anxiety, depression, irritability, trouble concentrating, lack of energy, sleep or appetite changes, breast fullness, joint or muscle pain, headache, weight gain are alleviated. Hyperandrogenic disorders: Ethinyl Estradiol reduces the accumulation of freely circulating androgens. This action is mediated through the elevation of SHBG (sex hormone binding globulin) which is a protein substance in the blood that binds DHEA-S (dehydroepiandrosterone), Testosterone and other androgenic hormones. Drospirenone with its direct androgen antagonist activity reduces the masculinization effects (oily skin, unwanted hair growth and irregular cycles) produced by excessive male type hormones or androgens in some women with disorders like acne, PCOS (polycystic ovary syndrome) and hirsutism. Regulation of menstrual cycle: Yasmin has the ultimate effect of promoting regular cycles, providing minimal flow, less pain and bloating. Cancer Prophylaxis: regular using of Yasmin pills benefits in female genital cancers such as ovarian and endometrial (womb/uterus). Both these cancers are prevented with such use of Yasmin, not only during therapy but long after use is discontinued. Yasmin doesn't protect you and your partner from sexually transmitted diseases (HIV and the others).

Dosage

Take one tablet a day orally, with food or after the meal. Do not crush or chew the tablet. Swallow the tablet whole with water. The cycle of using Yasmin takes 21 days. Take one tablet daily for 21 days consecutively. To achieve maximum contraceptive effectiveness, Yasmin must be taken exactly as directed and at intervals not exceeding 24 hours. It is recommended to take Yasmin tablets at the same time each day. Start the cycle of Yasmin according to its package directions (on the first day of your menstrual period or on the first Sunday of your menstrual period). After the last tablet, you should have 7 pill-free days. Continue taking Yasmin on the 28 day, regardless of whether or not periods have occurred or are still in progress.

Overdose

If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately. Symptoms of overdose are unusual vaginal bleeding, feeling drowsy, vomiting, extreme tiredness, nausea.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Yasmin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Yasmin if you are allergic to its components. Do not take Yasmin if you are using another oral contraception. Do not take Yasmin if you are pregnant, plan to have a baby, or during lactation. Do not take Yasmin if you suffer from or have a history of jaundice; liver disease; stroke; breast, liver or uterine cancer; unusual vaginal bleeding; blood clot; heart valve disorder; problems with circulation; severe high blood pressure. Do not smoke while taking Yasmin because it can cause heart attack, stroke or blood clots. Yasmin can make your skin more sensitive to sunlight. So, try to protect your skin. Do not take Yasmin if you are taking antibiotics: amoxicillin (e.g., Augmentin), ampicillin (e.g., Omnipen), doxycycline (e.g., Vibramycin, Doryx), griseofulvin (e.g., Grifulvin V, Fulvicin PG, Grisactin), minocycline (e.g., Minocin), penicillin (e.g., Bicillin, Veetids, Pen-Vee K), rifampin (e.g., Rifadin), rifabutin (e.g., Mycobutin), tetracycline (e.g., Robitet, Sumycin, Achromycin). Do not take Yasmin if you are also taking barbiturates: barbiturate (e.g., Amytal), butabarbital (e.g., Butisol), mephobarbital (e.g., Mebaral), secobarbital (e.g., Seconal) or phenobarbital (e.g., Solfoton, Luminal). Do not take Yasmin if you are also taking ascorbic acid (e.g., Vitamin C) or acetaminophen (e.g., Tylenol). Do not take Yasmin if you are also taking HIV medicines: amprenavir (e.g., Agenerase), atazanavir (e.g., Reyataz), tipranavir (e.g., Aptivus), indinavir (e.g., Crixivan), saquinavir (e.g., Invirase), ritonavir (e.g., Kaletra), fosamprenavir (e.g., Lexiva), ritonavir (e.g., Norvir) or nelfinavir (e.g., Viracept). Do not take Yasmin if you are also taking phenylbutazone (e.g., Butazolidin, Azolid). Do not take Yasmin if you are also taking seizure medicines: phenytoin (e.g., Dilantin), carbamazepine (e.g., Tegretol), felbamate (e.g., Felbatol), oxcarbazepine (e.g., Trileptal), topiramate (e.g., Topamax), or primidone (e.g., Mysoline). Do not take Yasmin if you are also taking St. John's Wort. Be careful with Yasmin if you suffer from or have a history of asthma, chest pain, heart condition, gallbladder or fibrocystic breast diseases, irregular menstrual periods, high blood pressure, high cholesterol, lumps, nodules, congestive heart failure, diabetes, epilepsy, depression. Be careful with Yasmin if you are going to have a surgery (dental or other). Do not consume alcohol while taking Yasmin, as it may cause excessive drowsiness, calmness, minor side effects. Yasmin doesn't protect you and your partner from sexually transmitted diseases (HIV and the others). Keep Yasmin away from children and don't give it to other people for using.

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The role of GA-mediated signalling in the control of seed germination. After 24 hours, tritiated thymidine was added to the culture dishes and incubated overnight. Myocardial performance, which was assessed using the working heart preparation, revealed a depression of function in untreated diabetics when compared with controls at most left atrial filling pressures. The efficacy of tissue factor pathway inhibitor (TFPI) as topically applied antithrombotic agent. Here, we show that F-actin-rich basal filopodia that link adjacent presumptive lens and retinal epithelia function as physical tethers that coordinate invagination. These data suggest that an increased cough reflex, as measured by capsaicin responsiveness, is an important contributor to the presence of cough in asthma and COPD, rather than cough being simply secondary to excessive airway secretions. Proliferation-promoting activity of MAF was observed throughout the period between days 12 and 15 of pregnancy, peaking at day 12. Effect of a whole-body vibration training modifying the training frequency of workouts per week in active adults.

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Magnetic resonance imaging (MRI) has important applications in musculoskeletal medicine. Furthermore, in addition to its abundance in spindle microtubules and the outer kinetochore interface during mitosis, Ska1 was enriched at centrosomes in cultured cells. Articulatory control of vowel length for contiguous jaw cycles: the effects of speaking rate and phonetic context. After separate injections into each of the six ipsilateral nipples, labelling occurred in all ipsilateral dorsal root ganglia between the 5th cervical and 6th lumbar spinal segments. Long-chain aminoalcohol and diamine derivatives induce apoptosis through a caspase-3 dependent pathway. Hypercholesterolemia causes erectile dysfunction that is associated with abnormalities in vascular smooth muscle and endothelial cells.

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Thickness Influence on In Vitro Biocompatibility of Titanium Nitride Thin Films Synthesized by Pulsed Laser Deposition. Investigation of the expression levels of efflux pumps in fluconazole-resistant Candida albicans isolates. The intention was also to make a longitudinal study of the changes in facial morphology during growth and during treatment with functional appliances. To review the reliability and validity literature and develop an understanding of these concepts as applied to managed care studies. CNVs were induced with small high-energy laser spots at short pulse duration by an argon green laser. When tested on fixed, paraffin-embedded tissue sections, they reacted with 97 percent of melanomas tested (58 of 60), including pigmented, unpigmented, primary, and metastatic melanoma. Learning about this will help us understand the ecology of individual populations in complex ecosystems. Voice intelligibility in patients who have undergone laryngectomies. Spatial and temporal pattern of smooth muscle cell differentiation during development of the vascular system in the mouse embryo. CA is dependent on cerebral vascular tone, the main determinant of which is the concentration of carbon dioxide (CO2).

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Integrating multibeam backscatter angular response, mosaic and bathymetry data for benthic habitat mapping. The aim of this study is to evaluate the role of erythropoietin (EPO) in neuroprotection for term newborn having HIE. Unfortunately, transforming growth factor-beta1 deficiency leads to a multifocal inflammatory disease affecting most organs of the body, which ultimately interferes with later stages of wound healing in these mice. Extracorporeal membrane oxygenation and retransplantation in lung transplantation: an analysis of the UNOS registry. To compare efficacy differences between fire filiform needle combined with mild moxibustion and gabapentin combined with sham acupuncture for postherpetic neuralgia (PHN). Decision support systems help to make reliable and standardized decisions in complex environments. A mental stress-induced reduction in pain sensitivity was observed in the absence of change in arterial pressure measured immediately before pulpar tests.

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Three of them were satisfied with their sexual life, whereas the remaining one complained the inadequate depth of the neovagina. The activities of MMP-2 and MMP-9 were determined by quantitative gelatinase zymography. Three patients with an increase in host cells rejected their grafts. The incidence of posttransplant lymphoproliferative disorder is higher after intestinal transplantation than after other solid organ transplants and the risk of cytomegalovirus enteritis is low with the use of cytomegalovirus seronegative donors. Furthermore, the presence of cysteine proteases in Plasmodium falciparum has presented additional opportunities for the development of chemical scaffolds that could potentially be utilized against all of the aforementioned parasites. Since the ban on 1,1,1-trichloroethane, the textile industry has been using trichloroethylene (TCE) as a spot remover to clean oil and grease stains from fabrics at inspection stations. Physiological Correlates of Bipolar Spectrum Disorders and their Treatment. A radiological terrorist attack on the United States is a possibility. These findings suggest that apoD may be related to the cognitive decline observed in AD patients and that apoD and apoE likely play different roles in the pathogenesis of AD. Although much research has focused on the protease/antiprotease theory of the pathogenesis of emphysema, less attention has been paid to the role of ROS in this condition.

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A new method that can dramatically improve the sensitivity and especially the specificity of skin naevi screening for melanoma by physicians is introduced. The limited information about this species is supplemented with data from other acarines, especially house dust mites and ticks. Effectiveness of coproovoscopic methods in the diagnosis of opisthorchiasis. Physical illness is likely to bring on psychological distress due to discomfort or threat of ill health. The tumors belong to the small group of serous carcinomas that arise from the peritoneum. Alloy multilayers and ternary nanostructures by direct-write approach.

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Much of this speculation centred on hopes that fMRI might eventually supersede the invasive intracarotid amobarbital procedure (IAP). Among reviews finding a statistically significant benefit of treatment, the effect size was large (median relative risk 0.55, range 0.09 to 0.93). Blue rubber bleb nevus syndrome: a clinical spectrum with correlation between cutaneous and gastrointestinal manifestations. Between the treated(39) and untreated (31) cases, there was no significant difference in gender, age, initial visual acuity, or size of the neovascular membrane. Efficient adsorption of Am(III) was realized with a fast rate to reach equilibrium (within 10 min). Ethyl 4-dodecyl-3,5-dimethyl-1H-pyrrole-2-carboxylate: intermolecular interactions in an amphiphilic pyrrole. The stable transfected 3T3-L1 cell line was established and the LYRM1 protein was expressed successfully.

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Synapse formation and function: insights from identified leech neurons in culture. Furthermore, the described tagging technology and methodology may prove transferable and allow for the labeling of other non-enveloped complex viruses. Radiotherapy in combination with simultaneous chemotherapy can improve survival of advanced esophageal adenocarcinoma. The clinicopathological factors for good prognosis include the increase in myocardial mass of ventricle evaluated by ventriculography and the histopathologic evidence for compensatory myocardial cell hypertrophy in the biopsied myocardium. Therefore, both active and inactive parallel fiber synapses can undergo changes at a postsynaptic locus as a result of associative pre- and postsynaptic activity.

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Induction of pro-inflammatory cytokines and chemokines has been implicated in the activation of the cascade of events resulting in pre-term labor. Changes of the phrenic nerve motor response in amyotrophic lateral sclerosis: longitudinal study. To detect gB recombinants, gpUL55 typing was applied to two variable zones (NTerminal and central). Electroretinography in the diagnosis and monitoring of treatment for neovascular age-related macular degeneration: Communication 1. Little is known about the relative impact of the organization of missions on aircrew well-being. Combining various kinds of needles for treatment is not only paying attention to the specificity of one kind of needles, but also emphasizing the whole function of all kinds of needles, which makes the new nine-needle formed the characteristic and distinct theory of its own.

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Characterisation of municipal solid waste and its recyclable contents of Guangzhou. As a complement to this approach, bioassays performed after LC/microfractionation of the extracts allow efficient localisation of the bioactive LC-peaks in the chromatograms. In contrast, intravenous injection elicited a Th2 type response, characterized by higher levels of IL-5 and high humoral immune response, resulting in a less efficient protection. A few selected applications of surface nonlinear optical spectroscopy. The results showed exposure to workplace bullying to be a significant predictor of mental health problems 5 years on, even after controlling for baseline mental health status, gender, age, job-change, job demands and job control, yet for men only. This demonstrates object-level intensity gain control in addition to the above object-level selective attentional gain. Ibutilide can cause torsades de pointes in a rabbit model of proarrhythmia dependent on the formation of early afterdepolarizations. Two-color flow cytometry analysis of lymphocyte subsets in patients with acute myocardial infarction and post-myocardial infarction syndrome.

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A 64 year old female presented was admitted with the principal complaints of fever, lower abdominal pain and malodorous vaginal discharge. It is useful in the diagnosis of HIV-Leishmania co-infection and as a prognostic marker. Identification of a putative methylenetetrahydrofolate reductase by sequence analysis of a 6.8 kb DNA fragment of yeast chromosome VII. Most patients of symptomatic osteoarthrosis of knee are associated with varus malalignment that is causative or contributory to painful arthrosis. Increased urinary levels of NMF and AMCC in the summer were attributed to increased percutaneous absorption of DMF resulting from the increased amount of water-soluble DMF absorbed by sweaty skin caused by the increased summertime room temperature and humidity.

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An evaluation of three methods used to assess gestational age of aboriginal neonates. Targeting calpains: A novel immunomodulatory approach for microbial infections. The strategy is unbiased only if all carriers share an identical risk. Probing the paradoxical pattern of cigarette smoking among African-Americans: low teenage consumption and high adult use. Reconstruction of the urethra with a Surgisis onlay patch in urethral reconstructive surgery: two case reports. An underlying arteriopathy may be suspected in many of these cases. Ureteric tip cells are remarkable for abnormal morphology and impaired expression of Ret and Wnt11, markers of tip cell differentiation. Recent trials have shown that high-dose statins reduce the risk of cerebrovascular events. In this paper, puberty and continuation of regular estrous cycles, ovulation rate and embryonic/fetal survival are the aspects of gilt reproductive efficiency to be considered. This study showed that at 8 weeks BH is significantly more effective than FL in terms of improving the total DHI score and the physical subscore.

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